Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay

Biochemistry

Volumn 36, Issue 5, 1997, Pages 1092-1099

  Ueno, Takamasa ^a,b   Mitsuya, Hiroaki ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b JAPAN ENERGY CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXY 2' FLUOROADENOSINE; 2',3' DIDEOXY 5 FLUOROCYTIDINE; 2',3' DIDEOXYADENOSINE; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; ADEFOVIR; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DEOXYRIBONUCLEOTIDE; HEPARIN; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; STAVUDINE; THYMIDINE TRIPHOSPHATE; ZALCITABINE; ZIDOVUDINE;

ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ASSAY; ENZYME KINETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION; NONHUMAN; PRIORITY JOURNAL;

ANTI-HIV AGENTS; BASE SEQUENCE; DEOXYRIBONUCLEOTIDES; DNA PRIMERS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPLATES, GENETIC;

FELIS CATUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0031046557     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962393d     Document Type: Article

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