Expression and distribution of the dentatorubral-pallidoluysian atrophy gene product (atrophin-1/drplap) in neuronal and non-neuronal tissues

Journal of the Neurological Sciences

Volumn 146, Issue 1, 1997, Pages 19-26

  Knight, Steven P ^a   Richardson, Matthew M ^a   Osmand, Alexander P ^a,b   Stakkestad, Anna ^a   Potter, Nicholas T ^a  

^a UNIVERSITY OF TENNESSEE MEDICAL CENTER   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

antibody; atrophin 1 drplap; CAG repeat; central nervous system; cerebral cortex; DRPLA; immunohistochemistry

Indexed keywords

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CATTLE; CHROMOSOME 12; CONTROLLED STUDY; DENTATORUBROPALLIDOLUYSIAN ATROPHY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT;

AMINO ACID SEQUENCE; ANIMALS; BRAIN CHEMISTRY; CATTLE; CHICKENS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; RABBITS; RATS; SAGUINUS;

EID: 0031044501     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(96)00266-3     Document Type: Article

References (38)

1. Allman, J. (1990) Evolution of neocortex. In: Jones, E.G. and Peters, A. (Eds.), Cerebral Cortex, Comparative Structure and Evolution of Cerebral Cortex, Part I, Vol. 8A. Plenum Press, New York, pp. 269-283.
2. Armstrong, D.C., W.C. Benzig, J. Evans, R.D. Terry, D. Shields and L.A. Hansen (1989) Substance P and somatostatin coexist within neuritic plaques: Implications for the pathogenesis of Alzheimer's disease. Neuroscience, 31: 663-671.
3. Baxendale, S., S. Abdulla, G. Elgar, D. Buck, M. Berks, G. Micklem, R. Durbin, G. Bates, S. Brenner, S. Beck and H. Lehrach (1995) Comparative sequence analysis of the human and pufferfish Huntington's disease genes. Nature Genet., 10: 67-76.
4. Burke, J.R., M.S. Wingfield, K.E. Lewis, A.D. Roses, J.E. Lee, C. Hulette, M.A. Pericak-Vance and J. Vance (1994) The Haw River Syndrome: Dentatorubral-pallidoluysian atrophy (DRPLA) in an African-American family. Nature Genet., 7: 521-524.
5. Burke, J.R., J.J. Enghild, M.E. Martin, Y.-S. Jou, R.M. Myers, A.D. Roses, J.M. Vance and W.J. Strittmatter (1996) Huntington and DRPLA proteins selectively interact with the enzyme GAPDH. Nature Med., 2: 347-349.
6. Burright, E.N., H.B Clark, A. Servadio, T. Matilla, R.M. Fedderson, W.S. Yunis, L.A. Duvick, H.Y. Zoghbi and H.T. Orr (1995) SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat. Cell, 82: 937-948.
7. Connarty, M., N.R. Dennis, C. Patch, J.N. Macpherson and J.F. Harvey (1996) Molecular re-investigation of patients with Huntington's disease in Wessex reveals a family with dentatorubral and pallidoluysian atrophy. Hum. Genet., 97: 76-78.
8. Diehl, H.-J., M. Schaich, R.-M. Budzinski and W. Stoffel (1986) Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proc. Natl. Acad. Sci. U.S.A., 83: 9807-9811.
9. DiFiglia, M., E. Sapp, K. Chase, C. Schwarz, A. Meloni, C. Young, E. Martin, J-P. Vonsattel, R. Carraway, S.A. Reeves, P.M. Boyce and N. Aronin (1995) Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron, 14: 1075-1081.
10. Kitamoto, T., K. Ogomori, J. Tateishi and S.B. Prusiner (1987) Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab. Invest., 57: 230-236.
11. Koide, R., T. Ikeuchi, O. Onodera, H. Tanaka, S. Igarashi, K. Endo, H. Takahashi, R. Kondo, A. Ishikawa, T. Hayashi, M. Saito, A. Tomoda, T. Miike, H. Naito, F. Ikuta and S. Tsuji (1994) Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nature Genet., 6: 9-13.
12. Komure, O., A. Sano, N. Nishino, N. Yamauchi, S. Ueno, K. Kondoh, N. Sano, M. Takahashi, N. Murayama, I. Kondo, S. Nagafuchi, M. Yamada and I. Kanazawa (1995) DNA analysis in hereditary dentatorubral-pallidoluysian atrophy: Correlation between CAG repeat length and phenotypic variation and molecular basis of anticipation. Neurology, 45: 143-149.
13. Landwehrmeyer, G.B., S.M. McNeil, L.S. Dure, P. Ge, H. Aizawa, Q. Huan, C.M. Ambrose, M.P. Duyao, E.D. Bird, E. Bonilla, M. de Young, A.J. Avila-Gonzales, N.S. Wexler, M. DiFiglia, J.F. Gusella, M.E. MacDonald, J.B. Penny, A.B. Young and J-P. Vonsattel (1995) Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals. Ann. Neurol., 37: 218-230.
14. Li, X.-J., S-H. Li, A.H. Sharp, F.C. Nucifora, Jr., G. Schilling, A. Lanahan, P. Worley, S.H. Snyder and C.A. Ross (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature, 378: 398-402.
15. Loev, S.J., R.L. Margolis, W.S. Young, S-H. Li, G. Schilling, R.G. Ashworth and C.A. Ross (1995) Cloning and expression of the rat atrophin-1 (DRPLA disease gene) homologue. Neurobiol. Disease, 2: 129-138.
16. Nagafuchi, S., H. Yanagisawa, K. Sato, T. Shirayama, E. Ohsaki, M. Bundo, T. Takeda, K. Tadokoro, I. Kondo, N. Murayama, Y. Tanaka, H. Kikushima, K. Umino, H. Kurosawa, T. Furukawa, K. Nihei, T. Inoue, A. Sano, O. Komure, M. Takahashi, T. Yoshizawa, I. Kanazawa and M. Yamada (1994a) Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p. Nature Genet., 6: 14-18.
17. Nagafuchi S., H. Yanagisawa, E. Ohsaki, T. Shirayama, K. Tadokoro, T. Inoue and M. Yamada (1994b) Structure and expression of the gene responsible for the triplet repeat disorder, dentatorubral and pallidoluysian atrophy (DRPLA). Nature Genet., 8: 177-182.
18. Naito, H. and S, Oyanagi (1982) Familial myoclonus epilepsy and choreoathetosis: Hereditary dentatorubral-pallidoluysian atrophy. Neurology, 32: 798-807.
19. Nørremølle, A., J.E. Nielsen, S.A. Sørensen and L. Hasholt (1995) Elongated CAG repeats of the B37 gene in a Danish family with dentato-rubro-pallido-luysian atrophy. Hum. Genet., 95: 313-318.
20. Onodera, O., M. Oyake, H. Takano, T. Takeshi, S. Igarashi and S. Tsuji (1995) Molecular cloning of a full-length cDNA for Dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS. Am. J. Hum. Genet., 57: 1050-1060.
21. Potter, N.T. and T.S. Stephens (1994) Humoral immune recognition of proteolipid protein (PLP) specific encephalitogenic epitopes in the SJL/J mouse. J. Neurosci. Res., 37: 15-22.
22. Potter, N.T., M.A. Meyer, A.W. Zimmerman, M.L. Eisenstadt and I.J. Anderson (1995) Molecular and clinical findings in family with dentatorubral-pallidoluysian atrophy. Ann. Neurol., 37: 273-277.
23. Richfield, E.K., K.A. Maguire-Zeiss, H.E. Vonkeman and P. Voorn (1995) Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients. Ann. Neurol., 38: 852-861.
24. Romer, A.S. (1962) The vertebrate body, 3rd Ed., W.B. Saunders, Philadelphia, pp. 546-547.
25. Ross, C.A. (1995) When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases. Neuron, 15: 493-496.
26. Schmitt, I., J.T. Epplen and O. Riess (1995) Predominant neuronal expression of the gene responsible for dentatorubral-pallidoluysian atrophy (DRPLA) in rat. Hum. Mol. Genet., 4: 1619-1624.
27. Sharp, A.H., S.J. Loev, G. Schilling, S-H. Li, X-J. Li, J. Bao, M.V. Wagster, J.A. Kotzuk, J.P. Steiner, A. Lo, J. Hedreen, S. Sisodia, S.H. Snyder, T.M. Dawson, D.K. Ryugo and C.A. Ross (1995) Widespread expression of Huntington's disease gene (IT15) protein product. Neuron, 14: 1065-1074.
28. Sotrel, A., P.A. Paskevich, D.K. Kiely, E.D. Bird, R.S. Williams and R.H. Myers (1991) Morphometric analysis of the prefrontal cortex in Huntington's disease. Neurology, 41: 1117-1123.
29. Stephens, T.S., M. Pakaski, M.B. Lees and N.T. Potter (1996) Identification and characterization of a B-cell determinant within the amphipathic domain (residues 178-238) of the myelin proteolipid protein. J. Neurosci. Res., 43: 545-553.
30. Takahashi, H., E. Ohama, H. Naito, S. Takeda, S. Nakashima, T. Makifuchi and F. Ikuta (1988) Hereditary dentatorubral-pallidoluysian atrophy: Clinical and pathologic variants in a family. Neurology, 38: 1065-1070.
31. Thompson, P.D. and B.L. Day (1995) Some aspects of higher motor disorders and their relationship to movement disorders associated with disease of subcortical nuclei. Curr. Opin. Neurol., 8: 303-305.
32. Trottier, Y., D. Devys, G. Imbert, F. Saudou, I. An, Y. Lutz, C. Weber, Y. Agid, E.C. Hirsch and J.-L. Mandel (1995) Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nature Genet., 10: 104-110.
33. Ulinski, P.S. and D. Margoliash (1990) Neurobiology of the reptile-bird transition, In: Jones, E.G. and Peters, A. (Eds.), Cerebral Cortex, Comparative Structure and Evolution of Cerebral Cortex, Part I, Vol. 8A. Plenum Press, New York, pp. 217-265.
34. Warner, T.T., G.G. Lennox, I. Janota and A.E. Harding (1994a) Autosomal-dominant Dentatorubropallidoluysian atrophy in the United Kingdom. Mov. Disord., 9: 289-296.
35. Warner, T.T., L. Williams and A.E. Harding (1994b) DRPLA in Europe. Nature Genet., 6: 225.
36. Warner, T.T., L.D. Williams, R.W.H. Walker, F. Flinter, S.A. Robb, S.E. Bundey, M. Honavar and A.E. Harding (1995) A clinical and molecular genetic study of Dentatorubropallidoluysian atrophy in four European families. Ann. Neurol., 37: 452-459.
37. Wood, J.D., J.C. MacMillan, P.S. Harper, P.R. Lowenstein and A.L. Jones (1996) Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain. Hum. Molec. Genet., 5: 481-487.
38. Yazawa, I., N. Nukina, H. Hashida, J. Goto, M. Yamada and I. Kanazawa (1995) Abnormal gene product identified in hereditary dentatorubral-pallidoluysian atrophy (DRPLA) brain. Nature Genet., 10: 99-103.