Distinct domains of adenovirus E1A interact with specific cellular factors to differentially modulate human immunodeficiency virus transcription

Journal of Virology

Volumn 71, Issue 3, 1997, Pages 2004-2012

  Parker, Scott F ^a   Felzien, Lisa K ^a   Perkins, Neil D ^a,c   Imperiale, Michael J ^a   Nabel, Gary J ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; TATA BOX; TRANSCRIPTION REGULATION; VIRUS TRANSCRIPTION;

EID: 0031040798     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.3.2004-2012.1997     Document Type: Article

References (56)

1. Abraham, S. E., S. Lobo, P. Yaciuk, H. H. Wang, and E. Moran. 1993. p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes. Oncogene 8:1639-1647.
2. Arany, Z., W. R. Sellers, D. M. Livingston, and R. Eckner. 1994. E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell 77:799-800.
3. Arias, J., A. S. Alberts, P. Brindle, F. X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common-nuclear factor. Nature 370:226-229.
4. Bannister, A. J., and T. Kouzarides. 1995. CBP-induced stimulation of c-Fos activity is abrogated by E1A. EMBO J. 14:4758-4762.
5. Berk, A. J. 1986. Adenovirus promoters and E1A transactivation. Annu. Rev. Genet. 20:45-79.
6. Betts, J. C., and G. J. Nabel. 1996. Differential regulation of NF-κB2(p100) processing and control by amino-terminal sequences. Mol. Cell. Biol. 16:6363-6371.
7. Bielinska, A., S. Krasnow, and G. J. Nabel. 1989. NF-κB-mediated activation of the human immunodeficiency virus enhancer: site of transcriptional initiation is independent of the TATA box. J. Virol. 63:4097-4100.
8. Bielinska, A., R. A. Shivdasani, L. Zhang, and G. J. Nabel. 1990. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science 250:997-1000.
9. Borrelli, E., R. Hen, and P. Chambon. 1984. Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature 312:608-612.
10. Chow, L. T., T. R. Broker, and J. B. Lewis. 1979. Complex splicing patterns of RNAs from the early regions of adenovirus-2. J. Mol. Biol. 134:265-303.
11. Dai, P., H. Akimaru, Y. Tanaka, D. Hou, T. Yasukawa, C. Kanei-Ishii, T. Takahashi, and S. Ishii. 1996. CBP as a transcriptional coactivator of c-Myb. Genes Dev. 10:528-540.
12. Duckett, C. S., N. D. Perkins, T. F. Kowalik, R. M. Schmid, E.-S. Huang, A. S. Baldwin, Jr., and G. J. Nabel. 1993. Dimerization of NF-KB2 with RelA (p65) regulates DNA binding, transcriptional activation, and inhibition by an IκB-α (MAD-3). Mol. Cell. Biol. 13:1315-1322.
13. Eckner, R., M. E. Ewen, D. Newsome, M. Gerdes, J. A. DeCaprio, J. B. Lawrence, and D. M. Livingston. 1994. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8:869-884.
14. Enkemann, S. A., S. F. Konieczny, and E. J. Taparow. 1990. Adenovirus 5 E1A represses muscle-specific enhancers and inhibits expression of the myogenic regulatory factor genes. MyD1 and myogenin. Cell Growth Differ. 1:375-382.
15. Geisberg, J. V., J. Chen, and R. P. Ricciardi. 1995. Subregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complex. Mol. Cell. Biol. 15:6283-6290.
16. Geisberg, J. V., W. S. Lee, A. J. Berk, and R. P. Ricciardi. 1994. The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein. Proc. Natl. Acad. Sci. USA 91:2488-2492.
17. Giordano, A., P. McCall, P. Whyte, and B. R. Franza, Jr. 1991. Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene product. Oncogene 6:481-486.
18. Grilli, M., J. J. Chiu, and M. J. Lenardo. 1993. NF-κB and rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1-62.
19. Hen, R., E. Borrelli, and P. Chambon. 1985. Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products. Science 230:1391-1394.
20. Hen, R., E. Borrelli, C. Fromental, P. Sassone-Corsi, and P. Chambon. 1986. A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products. Nature 321:249-251.
21. Janknecht, R., and A. Nordheim. 1996. Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP. Oncogene 12:1961-1969.
22. Janknect, R., and T. Hunter. 1996. Transcriptional control: versatile molecular glue. Curr. Biol. 6:951-954.
23. Jelsma, T. N., J. S. Howe, J. S. Mymryk, C. M. Evelegh, N. F. A. Cunniff, and S. T. Bayley. 1989. Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen. Virology 170:120-130.
24. Jones, N. 1995. Transcriptional modulation by the adenovirus E1A gene. Curr. Top. Microbiol. Immunol. 199:59-80.
25. Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414.
26. Kwok, R. P. S., J. R. Lundblad, J. C. Chrivia, J. P. Richards, H. P. Bachinger, R. G. Brennan, S. G. E. Roberts, M. R. Green, and R. H. Goodman. 1994. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-229.
27. Laspia, M. F., A. P. Rice, and M. B. Mathews. 1990. Synergy between HIV-1 Tat and adenovirus EIA is principally due to stabilization of transcriptional elongation. Genes Dev. 4:2397-2408.
28. Lee, W. S., C. C. Kao, G. O. Bryant, X. Liu, and A. J. Berk. 1991. Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor. Cell 67:365-376.
29. Leung, K., and G. J. Nabel. 1988. HTLV-I transactivator induces interleukin-2 receptor expression through an NF-κB-like factor. Nature 333:776-778.
30. Lew, D., S. E. Parker, T. Latimer, A. M. Abai, A. Kuwahara-Rundell, S. G. Don, Z. Yang, D. LaFace, S. H. Gromkowski, G. J. Nabel, M. Manthorpe, and J. Norman. 1995. Cancer gene therapy using plasmid DNA: pharmacokinetic study of DNA following injection in mice. Hum. Gene Ther. 6:553-564.
31. Lillie, J. W., and M. R. Green. 1989. Transcription activation by the adenovirus E1a protein. Nature 338:39-44.
32. Liu, F., and M. R. Green. 1994. Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains. Nature 348:520-525.
33. Mazzarelli, J. M., G. B. Atkins, J. V. Geisberg, and R. P. Ricciardi. 1995. The viral oncoproteins AdS E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110, Oncogene 11:1859-1864.
34. Moran, B., and B. Zerler. 1988. Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene. Mol. Cell. Biol. 8:1756-1764.
35. Moran, E., B. Zerler, T. M. Harrison, and M. B. Mathews. 1986. Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes. Mol. Cell. Biol. 6:3470-3480.
36. Nabel, G. J., S. A. Rice, D. M. Knipe, and D. Baltimore. 1988. Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells. Science 239:1299-1302.
37. Osborn, L., S. Kunkel, and G. J. Nabel. 1989. Tumor necrosis factor α and interleukin-1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB. Proc. Natl. Acad. Sci. USA 86:2336-2340.
38. Peeper, D. S., and A. Zantema. 1993. Adenovirus E1A proteins transform cells by sequestering regulatory proteins. Mol. Biol. Rep. 17:197-207.
39. Perkins, N. D., L. K. Felzien, J. C. Betts, K. Leung, D. H. Beach, and G. J. Nabel. Regulation of NF-κB by cyclin-dependenl kinases associated with the p300 co-activator. Science, in press.
40. Rice, A. P., and M. B. Mathews. 1988. Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein. Proc. Natl. Acad. Sci. USA 85:4200-4204.
41. Rikitake, Y., and E. Moran. 1992. DNA-binding properties of the E1A-associated 300-kilodalton protein. Mol. Cell. Biol. 12:2826-2836.
42. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
43. Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature 352:733-736.
44. Shenk, T., and J. Flint. 1991. Transcriptional and transforming activities of the adenovirus E1A proteins. Adv. Cancer Res. 57:47-85.
45. Siebenlist, U., G. Franzoso, and K. Brown. 1994. Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10:405-455.
46. Song, C., P. M. Loewenstein, and M. Green. 1995. Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat. J. Viroi. 69:2907-2911.
47. Song, C. Z., P. M. Loewenstein, K. Toth, and M. Green. 1995. Transcription factor TFIID is a direct functional target of the adenovirus E1A transcription-repression domain. Proc. Natl. Acad. Sci. USA 42:10330-10333.
48. Stein, R. W., M. Corrigan, P. Yaciuk, J. Whelan, and E. Moran. 1990. Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity. J. Virol. 64:4421-4427.
49. Tsang, S. X., G. F. Morris, M. Lu, and C. B. Morris. 1996. TATA-dependent repression of human immunodeficiency virus type-3 transcription by the adenovirus E1A 243R oncoprotein. Oncogene 12:819-826.
50. Velcich, A., and E. Ziff. 1985. Adenovirus E1A proteins repress transcription from the SV40 early promoter. Cell 40:705-716.
51. Ventura, A. M., M. Q. Arens, A. Srinivasan, and G. Chinnadurai. 1990. Silencing of human immunodeficiency virus long terminal repeat expression by an adenovirus E1A mutant. Proc. Natl. Acad. Sci. USA 87:1310-1314.
52. Wang, H. H., Y. Rikitake, M. C. Carter, P. Yaciuk, S. E. Abraham, B. Zerler, and E. Moran. 1993. Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth. J. Virol. 67:476-488.
53. Webster, L. C., and R. P. Ricciardi. 1991. trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor. Mol. Cell. Biol. 11:4287-4296.
54. Whyte, P., J. J. Buchkovich, J. M. Horowitz, S. H. Friend, M. Raybuck, R. A. Weinberg, and E. Harlow. 1988. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 334:124-129.
55. Whyte, P., H. E. Ruley, and E. Harlow. 1988. Two regions of the adenovirus early region 1A proteins are required for transformation. J. Virol. 62:257-265.
56. Whyte, P., N. M. Williamson, and E. Harlow. 1989. Cellular targets for transformation by the adenovirus E1A proteins. Cell 56:67-75.