Locomotor rhythm evoked by ventrolateral funiculus stimulation in the neonatal rat spinal cord in vitro

Journal of Neurophysiology

Volumn 77, Issue 1, 1997, Pages 200-206

  Magnuson, David S K ^a   Trinder, Tammy C ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LOCOMOTION; LUMBAR SPINAL CORD; NERVE CELL EXCITABILITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD MOTONEURON; SPINAL CORD STIMULATION; SPINAL CORD VENTRAL HORN; THORACIC SPINAL CORD;

EID: 0031035392     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.77.1.200     Document Type: Article

References (26)

1. ATSUTA, Y., GARCIA-RILL, E., AND SKINNER, R. D. Electrically induced locomotion in the in vitro brainstem-spinal cord preparation. Dev. Brain Res. 42: 309-312, 1988.
2. ATSUTA, Y., GARCIA-RILL, E., AND SKINNER, R. D. Characteristics of electrically induced locomotion in rat in vitro brain stem-spinal cord preparation. J. Neurophysiol. 64: 727-735, 1990.
3. CAZALETS, J. R., BORDE, M., AND CLARAC, F. Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat. J. Neurosci. 15: 4943-4951, 1995.
4. CAZALETS, J. R., BORDE, M., AND CLARAC, F. The synaptic drive from the spinal locomotor network to motoneurons in the newborn rat. J. Neurosci. 16: 298-306, 1996.
5. CAZALETS, J. R., SQUALLI-HOUSSAINI, Y., AND CLARAC, F. Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat. J. Physiol. Lond. 455: 187-204, 1992.
6. COWLEY, K. C. AND SCHMIDT, B. J. Some limitations of ventral root re- cordings for monitoring locomotion in the in vitro neonatal rat spinal cord preparation. Neurosci. Lett. 171: 142-146, 1994a.
7. COWLEY, K. C. AND SCHMIDT, B. J. A comparison of motor patterns induced by N-methyl-D-aspartate, acetylcholine and serotonin in the in vitro neonatal rat spinal cord. Neurosci. Lett. 171: 147-150, 1994b.
8. DAI, X., DOUGLAS, J. R., NAGY, J. I., NOGA, B. R., AND JORDAN, L. M. Localization of spinal neurons activated during locomotion using the c-fos immunohistochemical method. Soc. Neurosci. Abstr. 16: 889, 1990.
9. DREW, T. AND ROSSIGNOL, S. Phase-dependent responses evoked in limb muscles by stimulation of medullary reticular formation during locomotion in thalamic cats. J. Neurophysiol. 52: 653-675, 1984.
10. IWAHARA, T., ATSUTA, Y., GARCIA-RILL, E., AND SKINNER, R. D. Locomotion induced by spinal cord stimulation in the neonatal rat in vitro. Somatosens. Res. 8: 281-287, 1991.
11. JORDAN, L. M. Brainstem and spinal cord mechanisms for the initiation of locomotion. In: Neurobiological Basis of Human Locomotion, edited by M. Shimamura, S. Grillner, and V. R. Edgerton. Tokyo: Jpn. Sci. Soc./ Springer-Verlag, 1991, p. 3-20.
12. KJEHN, O. AND KJÆRULFF, O. Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat. J. Neurophysiol, 15: 1472-1482, 1996.
13. KJÆRULFF, O., BARAJON, I., AND KIEHN, O. Distribution of sulforhodamine labelled cells in the neonatal rat spinal cord following chemically induced locomotor activity in vitro. J. Physiol. Lond. 478: 265-273, 1994.
14. KJÆRULFF, O. AND KJEHN, O. Localization of the central pattern generator for hindlimb locomotion in the neonatal rat in vitro. A lesion study. Soc. Neurosci. Abstr. 20: 717.5, 1994.
15. KJÆRULFF, O. AND KIEHN, O. Rostra/caudal and left/right coordination of the rhythmic activity in the lumbar spinal cord of the newborn rat in vitro (Abstract). Proc. Int. Symp. Neurons Networks Mot. Behav. 11-19: 43, 1995.
16. KUDO, N. AND YAMADA, T. N-methyl-DL-aspartate locomotor activity in a spinal cord hindlimb muscles preparation of the newborn rat studied in vitro. Neurosci. Lett. 75: 43-48, 1987.
17. MACLEAN, J. N., HOCHMAN, S., AND MAGNUSON, D.S.K. Lamina VII neurons are rhythmically active during locomotor-like activity in the neonatal rat spinal cord. Neurosci. Lett. 197: 9-12, 1995.
18. MAGNUSON, D.S.K., SCHRAMM, M. J., AND MACLEAN, J. N. Long-duration, frequency-dependent motor responses evoked by ventrolateral funiculus stimulation in the neonatal rat spinal cord. Neurosci. Lett. 192: 97-100, 1995.
19. NOGA, B. R., FORTIER, P. A., KRIELLAARS, D. J., DAI, X., DETILLIEUX, G. R., AND JORDAN, L. M. Field potential mapping of neurons in the lumbar spinal cord activated following stimulation of the mesencephalic locomotor region. J. Neurosci. 15: 2203-2217, 1995.
20. NOGA, B. R., KRIELLAARS, D. J., AND JORDAN, L. M. The effect of selective brainstem or spinal cord lesions on treadmill locomotion. J. Neurosci. 11: 1691-1700, 1991.
21. SCHMIDT, B. J. Afterhyperpolarization modulation in lumbar motoneurons during locomotor-like rhythmic activity in the neonatal rat spinal cord in vitro. Exp. Brain Res. 99: 214-222, 1994.
22. SHEFCHYK, S. J. AND JORDAN, L. M. Excitatory and inhibitory postsynaptic potentials in alpha-motoneurons produced during fictive locomotion by stimulation of the mesencephalic locomotor region. J. Neurophysiol. 6: 1345-1355, 1985.
23. SKINNER, R. D. AND GARCIA-RILL, E. The mesencephalic locomotor region (MLR) in the rat. Brain Res. 323: 385-389, 1984.
24. STEEVES, J. D. AND JORDAN, L. M. Localization of a descending pathway in the spinal cord which is necessary for controlled treadmill locomotion. Neurosci. Lett. 20: 283-288, 1980.
25. WHEATLEY, M., JOVANOVIC, K., STEIN, R. B., AND LAWSON, V. The activity of interneurons during locomotion in the in vitro necturus spinal cord. J. Neurophysiol. 71: 2025-2032, 1994.
26. YAMAGUCHI, T. Descending pathways eliciting forelimb stepping in the lateral funiculus: experimental studies with stimulation and lesion of the cervical cord in decerebratc cats. Brain Res. 379: 125-136, 1986.