Antitumor agents. 169. Dysoxylum cumingianum. V. Cumingianosides P and Q, new cytotoxic triterpene glucosides with an apotirucallane-type skeleton from Dysoxylum cumingianum

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 1, 1997, Pages 202-206

  Fujioka, Toshihiro ^a   Sakurai, Akio ^a   Mihashi, Kunihide ^a   Kashiwada, Yoshiki ^b   Chen, Ih Sheng ^c   Lee, Kuo Hsiung ^d  

^a FUKUOKA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

apotirucallane glucoside; cytotoxicity; Dysoxylum cumingianum; Meliaceae; triterpene; triterpene glucoside

Indexed keywords

ANTINEOPLASTIC AGENT; CUMINGIANOSIDE P; CUMINGIANOSIDE Q; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG CONFORMATION; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; LUNG NON SMALL CELL CANCER; PLANT LEAF; STRUCTURE ACTIVITY RELATION;

EID: 0031033755     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.202     Document Type: Article

References (7)

1. For Antitumor Agents part 168 and Dysoxylum cumingianum. IV see: Fujioka T., Sakurai A., Mihashi K., Kashiwada Y., Chen I.-S., Lee K.-H., Chem. Pharm. Bull. 45, 68-74 (1997).
2. a) Kashiwada Y., Fujioka T., Chang J. J., Chen I. S., Mihashi K., Lee K.-H., Bioorganic & Medicinal Chemistry Letters, 2, 395-398 (1992);
3. b) Idem, J. Org. Chem., 57, 6948-6953 (1992);
4. c) Kashiwada Y., Fujioka T., Mihashi K., Marubayashi N., Mizuki K., Chen I.-S., Lee K.-H., J. Nat. Prod., 58, 495-503 (1995).
5. 1)
6. 1)
7. Boyd M. B., Paul K. D., Drug. Development Res., 34, 91-109 (1995).