Understanding the molecular basis of cell migration; Implications for clinical therapy in multiple sclerosis

Clinical Science

Volumn 92, Issue 2, 1997, Pages 113-122

  Milner, Richard ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Demyelination; Extracellular matrix; Integrin; Migration; Multiple sclerosis; Oligodendrocyte; Oligodendrocyte precursor; Remyelination; Transplantation

Indexed keywords

BETA INTERFERON; CELL ADHESION MOLECULE; INTEGRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; MOLECULAR BIOLOGY; MOUSE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL;

EID: 0031032784     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0920113     Document Type: Article

References (57)

1. Bernard CCA, de Rosbo NK. Multiple sclerosis: an autoimmune disease of multifactorial aetiology. Curr Opin Immunol 1992; 4: 760-5.
2. ffrench-Constant C. Pathogenesis of multiple sclerosis. Lancet 1994; 343: 271-5.
3. Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996; 85: 299-302.
4. Reingold SC. Advances in the understanding and treatment of multiple sclerosis. J Neuroimmunol 1993; 44: 221-4.
5. Panitch HS, Heracl RI, Schindler J, Johnson KP. Treatment of MS with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987; 37: 1097-102.
6. Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin. Nature (London) 1992; 356: 63-6.
7. Archelos JJ, Jung S, Maurer M, et al. Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM-1. Ann Neurol 1993; 34: 145-54.
8. Paty DW, Li DKB, Group TUMMS, Group IMSS. Interferon beta-1b is effective in relapsing/remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomised, double blind, placebo controlled trial. Neurology 1993; 43: 662-7.
9. Warf BC, Fok-Seang J, Miller RH. Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord. J Neurosci 1991; 11: 2477-88.
10. Pringle NP, Richardson WD. A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendroglial lineage. Development 1993; 117: 525-33.
11. Levison SW, Chuang C, Abramson BJ, Goldman JE. The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated. Development 1993; 119: 611-22.
12. Small RK, Riddle P, Noble M. Evidence for migration of oligodendrocyte-type-2 astrocyte progenitor cells into the developing rat optic nerve. Nature (London) 1987; 328: 155-7.
13. Noble M, Murray K, Stroobant P, Waterfield M, Riddle P. Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte type-2-astrocyte progenitor cell. Nature (London) 1988; 333: 560-5.
14. Warrington AE, Barbarese E, Pfeiffer SE. Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts. J Neurosci Res 1993; 34: 1-13.
15. Blakemore WF, Crang AJ. Transplantation of glial cells into areas of demyelination in adult rat spinal cord. In: Dunnet SB, Bjorklund A, eds. Neural transplantation: a practical approach. Oxford: Oxford University Press, 1992: 105-22.
16. Franklin RJM. Reconstructing myelin-deficient environments in the CNS by glial cell transplantation. Semin Neurosci 1993; 5: 443-51.
17. Groves AK, Barnett SC, Franklin RJM, et al. Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells. Nature (London) 1993; 362: 453-5.
18. Louis JC, Magal E, Muir D, Manthorpe M, Varon S. CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes. J Neurosci Res 1992; 31: 193-204.
19. Franklin R, Bayley S, Milner R, ffrench-Constant C, Blakemore W. Differentiation of the O-2A progenitor cell line CG-4 into oligodendrocytes and astrocytes following transplantation into glia-deficient areas of CNS white matter. Glia 1995; 13: 39-44.
20. Franklin RJM, Bayley SA, Blakemore WF. Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Exp Neurol 1996; 137: 263-76.
21. Hynes RO. Integrins: versatility, modulation and signaling in cell adhesion. Cell 1992; 69: 11-25.
22. Hynes RO, Lander AD. Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 1992; 68: 303-22.
23. Adams JC, Watt FM. Regulation of development and differentiation by the extracellular matrix. Development 1993; 117: 1183-98.
24. Bronner-Fraser M. An antibody to a receptor for fibronectin and laminin perturbs cranial neural crest development in vivo. Dev Biol 1986; 117: 528-36.
25. Galileo DS, Majors J, Horwitz AF, Sanes JR. Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo. Neuron 1992; 9: 1117-31.
26. Mitjans F, Sander D, Adan J, et al. An anti-αv integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice. J Cell Sci 1995; 108: 2825-38.
27. Fassler R, Pfaff M, Murphy J, et al. Lack of β1 integrin gene in embryonic stem cells affects morphology, adhesion and migration but not integration into the inner cell mass of blastocyts. J Cell Biol 1995; 128: 979-88.
28. Milner R, ffrench-Constant C. A developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation. Development 1994; 120: 3497-506.
29. Einheber S, Milner TA, Giancotti F, Salzer JL. Axonal regulation of Schwann cell integrin expression suggests a role for α6β4 in myelination. J Cell Biol 1993; 123: 1223-36.
30. Niessen CM, Cremona O, Daams H, Ferraresi S, Sonnenberg A, Marchisio PC. Expression of the integrin α6β4 in peripheral nerves: localization in Schwann and perineural cells and different variants of the β4 subunit. J Cell Sci 1994; 107: 543-52.
31. Feltri ML, Scherer SS, Nemni R, et al. β4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Development 1994; 120: 1287-301.
32. Shaw CE, Milner R, Compston AS, ffrench-Constant C. Analysis of integrin expression on oligodendrocytes during axo-glial interaction by using rat-mouse xenocultures. J Neurosci 1996; 16: 1163-72.
33. Varani J, Orr W, Ward PA. A comparison of the migration patterns of normal and malignant cells in two assay systems. Am J Pathol 1978; 90: 159-72.
34. Milner R, Edwards G, Streuli C, ffrench-Constant C. A role in migration for the αvβ1 integrin expressed on oligodendrocyte precursors. J Neurosci 1996; 16: 7240-52.
35. Koivunen E, Gay DA, Ruoslahti E. Selection of peptides binding to the α5β1 integrin from phage display library. J Biol Chem 1993; 268: 20205-10.
36. Hall DE, Reichardt LF, Crowley E, et al. The α1β1 and α6β1 integrin heterodimers mediate cell attachment to distinct sites on laminin. J Cell Biol 1990; 110: 2175-84.
37. Sonnenberg A, Modderman PW, Hogervorst F. Laminin receptor on platelets is the integrin VLA-6. Nature (London) 1988; 336: 487-9.
38. Morissette N, Carbonetto S. Merosin is found within the pathway of avian retinal projections during development. Soc Neurosci Abstr 1993; 19: 1086.
39. Chun JJM, Shatz CJ. A fibronectin-like molecule is present in the developing cat cerebral cortex and is correlated with subplate neurons. J Cell Biol 1988; 106: 857-72.
40. Sheppard AM, Hamilton SK, Pearlman AL. Changes in the distribution of extracellular matrix components accompany early morphogenetic events of mammalian cortical development. J Neurosci 1991; 11: 3928-42.
41. Neugebauer KM, Emmett CJ, Venstrom KA, Reichardt LF. Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins. Neuron 1991; 6: 345-58.
42. Einheber S, Milner TA, Preissner KT, Salzer JL. Vitronectin is associated with myelin sheaths in the adult rat brain. Soc Neurosci Abstr 1996; 29: 11.
43. Cardwell MC, Rome LH. Evidence that an RGD-dependent receptor mediates the binding of oligodendrocytes to a novel ligand in a glial-derived matrix. J Cell Biol 1988; 107: 1541-9.
44. Elices MJ, Osborn L, Takada Y, et al. VCAM-1 on activated endothelium interacts with the leucocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 1990; 60: 577-84.
45. Almeida EAC, Huovila A-PJ, Sutherland AE, et al. Mouse egg integrin α6β1 functions as a sperm receptor. Cell 1995; 81: 1095-104.
46. Wolfsberg TG, Straight PD, Gerena RL, et al. ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev Biol 1995; 169: 378-83.
47. Ruppert M, Aigner S, Hubbe M, Yagita H, Altevogt P. The L1 adhesion molecule is a cellular ligand for VLA-5. J Cell Biol 1995; 131: 1881-91.
48. Montgomery AMP, Becker JC, Siu C-H, et al. Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin αvβ3. J Cell Biol 1996; 132: 475-85.
49. Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, Fassler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins. Nature (London) 1996; 380: 171-5.
50. Stephens LE, Sonne JE, Fitzgerald ML, Damsky CH. Targeted deletion of β1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression. J Cell Biol 1993; 123: 1607-20.
51. Keely PJ, Fong AM, Zutter MM, Santoro SS. Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense α2 integrin mRNA in mammary cells. J Cell Sci 1995; 108: 595-607.
52. Leavesley DI, Ferguson GD, Wayner EA, Cheresh DA. Requirement of the integrin β3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen. J Cell Biol 1992; 117: 1101-7.
53. Beauvais A, Erickson CA, Goins T, et al. Changes in the fibronectin-specific integrin expression pattern modify the migratory behaviour of sarcoma S180 cells in vitro and in the embryonic environment. J Cell Biol 1995; 128: 699-713.
54. Prineas JW, Kwon EE, Goldenberg PZ, Ilyas AA, Quarles RH. Multiple sclerosis: oligodendrocyte proliferation and differentiation in fresh lesions. Lab Invest 1989; 61: 489-503.
55. Brück W, Schmied M, Suchanek G, et al. Oligodendrocytes in the early course of multiple sclerosis. Ann Neurol 1994; 35: 65-73.
56. ffrench-Constant C, Raff MC. Proliferating bipotential glial progenitor cells in adult rat optic nerve. Nature (London) 1986; 319: 499-502.
57. Wolswijk G, Noble M. Cooperation between PDGF and FGF converts slowly dividing O-2A adult progenitor cells to rapidly dividing cells with characteristics of O-2A perinatal progenitor cells. J Cell Biol 1992; 118: 889-900.