메뉴 건너뛰기




Volumn 53, Issue 2, 1997, Pages 241-244

Antagonism of estrogen receptor and calmodulin association by antiestrogens is not dependent on an interaction with calmodulin

Author keywords

cAMP phosphodiesterase; steroidal antiestrogens; tamoxifen analogues; triphenylethylenes

Indexed keywords

CALMODULIN; CYCLIC AMP PHOSPHODIESTERASE; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; NAFOXIDINE; TAMOXIFEN;

EID: 0031029244     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00603-X     Document Type: Article
Times cited : (3)

References (19)
  • 2
    • 0026754030 scopus 로고
    • Antagonistic effect of triphenylethylenic antiestrogens on the association of estrogen receptor to calmodulin
    • Bouhoute A and Leclercq G, Antagonistic effect of triphenylethylenic antiestrogens on the association of estrogen receptor to calmodulin. Biochem Biophys Res Commun 184: 1432-1440, 1992.
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 1432-1440
    • Bouhoute, A.1    Leclercq, G.2
  • 3
    • 0021321610 scopus 로고
    • Tamoxifen is a calmodulin antagonist in the activation of cyclic AMP phosphodiesterase
    • Lam HYP, Tamoxifen is a calmodulin antagonist in the activation of cyclic AMP phosphodiesterase. Biochem Biophys Res Commun 118: 27-32, 1984.
    • (1984) Biochem Biophys Res Commun , vol.118 , pp. 27-32
    • Lam, H.Y.P.1
  • 5
    • 0025193824 scopus 로고
    • 2+ -dependent binding of tamoxifen to calmodulin isolated from bovine brain
    • 2+ -dependent binding of tamoxifen to calmodulin isolated from bovine brain. Cancer Res 50: 2753-2758, 1990.
    • (1990) Cancer Res , vol.50 , pp. 2753-2758
    • Lopes, M.C.F.1    Vale, M.G.P.2    Carvalho, A.P.3
  • 6
    • 0025277529 scopus 로고
    • Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; correlations with cytotoxicity
    • Rowlands MG, Parr IB, McCague R, Jarman M and Goddard PM, Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; correlations with cytotoxicity. Biochem Pharmacol 40: 283-289, 1990.
    • (1990) Biochem Pharmacol , vol.40 , pp. 283-289
    • Rowlands, M.G.1    Parr, I.B.2    McCague, R.3    Jarman, M.4    Goddard, P.M.5
  • 7
    • 0019941226 scopus 로고
    • Importance of the alkylaminoethoxy side chain for estrogenic and antiestrogenic actions of tamoxifen and trioxifene in the mature rat uterus
    • Jordan VC and Gosden B, Importance of the alkylaminoethoxy side chain for estrogenic and antiestrogenic actions of tamoxifen and trioxifene in the mature rat uterus. Mol Cell Endocrinol 27: 291-306, 1982.
    • (1982) Mol Cell Endocrinol , vol.27 , pp. 291-306
    • Jordan, V.C.1    Gosden, B.2
  • 8
    • 0021947987 scopus 로고
    • Differential effects of tamoxifen and analogs with non-basic side chain on cell proliferation in vitro
    • Murphy LC and Sutherland RL, Differential effects of tamoxifen and analogs with non-basic side chain on cell proliferation in vitro. Endocrinology 116: 1071-1978, 1985.
    • (1985) Endocrinology , vol.116 , pp. 1071-1978
    • Murphy, L.C.1    Sutherland, R.L.2
  • 9
    • 0028977917 scopus 로고
    • Antiestrogenic activity of two 11 β-estradiol derivatives on MCF-7 breast cancer cells
    • Jin L, Borras M, Lacroix M, Legros N and Leclercq G, Antiestrogenic activity of two 11 β-estradiol derivatives on MCF-7 breast cancer cells. Steroids 60: 512-518, 1995.
    • (1995) Steroids , vol.60 , pp. 512-518
    • Jin, L.1    Borras, M.2    Lacroix, M.3    Legros, N.4    Leclercq, G.5
  • 10
    • 0024319781 scopus 로고
    • Inhibition of tamoxifen-stimulated growth of a MCF-7 tumour variant in athymic mice by novel steroidal antiestrogens
    • Gottardis MM, Jiang SY, Jeng MH and Jordan VC, Inhibition of tamoxifen-stimulated growth of a MCF-7 tumour variant in athymic mice by novel steroidal antiestrogens. Cancer Res 49: 4090-4093, 1989.
    • (1989) Cancer Res , vol.49 , pp. 4090-4093
    • Gottardis, M.M.1    Jiang, S.Y.2    Jeng, M.H.3    Jordan, V.C.4
  • 11
    • 0343441013 scopus 로고
    • New 7-aryl-substituted, 19 norsteroids useful as proliferative, antiestrogens and/or estrogens and their preparation, use as medicines and pharmaceutical compositions. Eur. Patent Appl. EP 280,618(31/08/1988)
    • Nique F, Nedelec L, Bouton MM and Philibert D, New 7-aryl-substituted, 19 norsteroids useful as proliferative, antiestrogens and/or estrogens and their preparation, use as medicines and pharmaceutical compositions. Eur. Patent Appl. EP 280,618(31/08/1988). Chemical Abstr 110: 115181, 1989.
    • (1989) Chemical Abstr , vol.110 , pp. 115181
    • Nique, F.1    Nedelec, L.2    Bouton, M.M.3    Philibert, D.4
  • 12
    • 0028346244 scopus 로고
    • Estradiol derivatives bearing the side chain of tamoxifen antagonise the association between the estrogen receptor and calmodulin
    • Bouhoute A and Leclercq G, Estradiol derivatives bearing the side chain of tamoxifen antagonise the association between the estrogen receptor and calmodulin. Biochem Pharmacol 47: 748-751, 1994.
    • (1994) Biochem Pharmacol , vol.47 , pp. 748-751
    • Bouhoute, A.1    Leclercq, G.2
  • 14
    • 0030066214 scopus 로고    scopus 로고
    • Homologs of idoxifene: Variation of estrogen receptor binding and calmodulin antagonism with chain lengths
    • Hardcastle IR, Rowlands MG, Grimshaw R, Houghton J, Jarman M, Sharff A and Neidle S. Homologs of idoxifene: Variation of estrogen receptor binding and calmodulin antagonism with chain lengths. J Med Chem 39: 999-1004, 1996.
    • (1996) J Med Chem , vol.39 , pp. 999-1004
    • Hardcastle, I.R.1    Rowlands, M.G.2    Grimshaw, R.3    Houghton, J.4    Jarman, M.5    Sharff, A.6    Neidle, S.7
  • 15
    • 0022922221 scopus 로고
    • Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-5H-benzocycloheptene
    • McCague R, Kuroda R, Leclercq G and Stoessel S, Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-5H-benzocycloheptene. J Med Chem 29: 2053-2059, 1986.
    • (1986) J Med Chem , vol.29 , pp. 2053-2059
    • McCague, R.1    Kuroda, R.2    Leclercq, G.3    Stoessel, S.4
  • 16
    • 0028081184 scopus 로고
    • Evidence that tamoxifen binds to calmodulin in a conforma-tion different to that when binding to estrogen receptors, through structure-activity study on ring-fused analogues
    • McCague R, Rowlands MG, Grimshaw R and Jarman M, Evidence that tamoxifen binds to calmodulin in a conforma-tion different to that when binding to estrogen receptors, through structure-activity study on ring-fused analogues. Biochem Pharmacol 48: 1355-1361, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1355-1361
    • McCague, R.1    Rowlands, M.G.2    Grimshaw, R.3    Jarman, M.4
  • 18
    • 0028231192 scopus 로고
    • Agonist-antagonist activity of antiestrogens in the human breast cancer cell line MCF-7: A hypothesis for the interaction with a site distinct from the estrogen binding site
    • Berthois Y, Pons M, Dussert C, Paulet AC and Martin PM, Agonist-antagonist activity of antiestrogens in the human breast cancer cell line MCF-7: A hypothesis for the interaction with a site distinct from the estrogen binding site. Mol Cell Endocrinol 99: 259-268, 1992.
    • (1992) Mol Cell Endocrinol , vol.99 , pp. 259-268
    • Berthois, Y.1    Pons, M.2    Dussert, C.3    Paulet, A.C.4    Martin, P.M.5
  • 19
    • 0029028824 scopus 로고
    • A new interpretation of antiestrogen action
    • Eds. Henderson D, Philibert D, Roy A and Teutsch G. New York Academy of Science, New York
    • Hedden A, Muller V and Jensen EV, A new interpretation of antiestrogen action. In: Steroid Receptors and Antihormones; Annals of the New York Academy of Science (Eds. Henderson D, Philibert D, Roy A and Teutsch G), pp. 109-120. New York Academy of Science, New York, 1995.
    • (1995) Steroid Receptors and Antihormones; Annals of the New York Academy of Science , pp. 109-120
    • Hedden, A.1    Muller, V.2    Jensen, E.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.