Homologs of idoxifene: Variation of estrogen receptor binding and calmodulin antagonism with chain length

Journal of Medicinal Chemistry

Volumn 39, Issue 4, 1996, Pages 999-1004

  Hardcastle, Ian R ^a   Rowlands, Martin G ^a   Grimshaw, Rachel M ^a   Houghton, John ^a   Jarman, Michael ^a   Sharff, Andrew ^a   Neidle, Stephen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DICHLORO 2,3 DIPHENYLCYCLOPROPANE; CALMODULIN INHIBITOR; DROLOXIFENE; ESTROGEN RECEPTOR; IDOXIFENE;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DRUG ANTAGONISM; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; REACTION ANALYSIS; RECEPTOR BINDING; STRUCTURE ANALYSIS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BINDING, COMPETITIVE; CALMODULIN; CYTOSOL; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN ANTAGONISTS; FEMALE; KINETICS; MOLECULAR STRUCTURE; RADIOLIGAND ASSAY; RATS; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; TAMOXIFEN; UTERUS;

EID: 0030066214     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9505472     Document Type: Article

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