메뉴 건너뛰기




Volumn 62, Issue 7, 1996, Pages 2540-2546

Production of a polyhydroxyalkanoate biopolymer in insect cells with a modified eucaryotic fatty acid synthase

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; BIOPOLYMER; FATTY ACID SYNTHASE; POLYESTER;

EID: 0030006096     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.7.2540-2546.1996     Document Type: Article
Times cited : (35)

References (48)
  • 2
    • 0025226099 scopus 로고
    • Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates
    • Anderson, A. J., and E. A. Dawes. 1990. Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbiol. Rev. 54:450-472.
    • (1990) Microbiol. Rev. , vol.54 , pp. 450-472
    • Anderson, A.J.1    Dawes, E.A.2
  • 3
    • 0025581498 scopus 로고
    • Plastics from bacteria and for bacteria: Poly(β-hydroxyalkanoates) as natural, biocompatible, and biodegradable polyesters
    • Brandl, H., R. A. Gross, R. W. Lenz, and R. C. Fuller. 1990. Plastics from bacteria and for bacteria: poly(β-hydroxyalkanoates) as natural, biocompatible, and biodegradable polyesters. Adv. Biochem. Eng. Biotechnol. 41:77-93.
    • (1990) Adv. Biochem. Eng. Biotechnol. , vol.41 , pp. 77-93
    • Brandl, H.1    Gross, R.A.2    Lenz, R.W.3    Fuller, R.C.4
  • 4
    • 0029027352 scopus 로고
    • Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage
    • Cortes, J., K. E. H. Wiesmann, G. A. Roberts, M. J. B. Brown, J. Staunton, and P. F. Leadlay. 1995. Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage. Nature (London) 268:1487-1489.
    • (1995) Nature (London) , vol.268 , pp. 1487-1489
    • Cortes, J.1    Wiesmann, K.E.H.2    Roberts, G.A.3    Brown, M.J.B.4    Staunton, J.5    Leadlay, P.F.6
  • 5
    • 0015823869 scopus 로고
    • The role and regulation of energy reserve polymers in microorganisms
    • Dawes, E. A., and P. J. Senior. 1973. The role and regulation of energy reserve polymers in microorganisms. Adv. Microb. Physiol. 10:135-266.
    • (1973) Adv. Microb. Physiol. , vol.10 , pp. 135-266
    • Dawes, E.A.1    Senior, P.J.2
  • 6
    • 0025045789 scopus 로고
    • Biosynthesis and characterization of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Alcaligenes eutrophus
    • Doi, Y., A. Segawa, and M. Kunioka. 1990. Biosynthesis and characterization of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Alcaligenes eutrophus. Int. J. Biol. Macromol. 12:106-111.
    • (1990) Int. J. Biol. Macromol. , vol.12 , pp. 106-111
    • Doi, Y.1    Segawa, A.2    Kunioka, M.3
  • 8
    • 0020684899 scopus 로고
    • Polymeric beta-hydroxyalkanoates from environmental samples and Bacillus megaterium
    • Findlay, R. H., and D. C. White. 1983. Polymeric beta-hydroxyalkanoates from environmental samples and Bacillus megaterium. Appl. Environ. Microbiol. 45:71-78.
    • (1983) Appl. Environ. Microbiol. , vol.45 , pp. 71-78
    • Findlay, R.H.1    White, D.C.2
  • 9
    • 0025083033 scopus 로고
    • Production of unsaturated polyesters by Pseudomonas oleovorans
    • Fritzsche, K., R. W. Lenz, and R. C. Fuller. 1990. Production of unsaturated polyesters by Pseudomonas oleovorans. Int. J. Biol. Macromol. 12:85-91.
    • (1990) Int. J. Biol. Macromol. , vol.12 , pp. 85-91
    • Fritzsche, K.1    Lenz, R.W.2    Fuller, R.C.3
  • 10
    • 0025109455 scopus 로고
    • Bacterial polyesters containing branched poly(beta-hydroxyalkanoate) units
    • Fritzsche, K., R. W. Lenz, and R. C. Fuller. 1990. Bacterial polyesters containing branched poly(beta-hydroxyalkanoate) units. Int. J. Biol. Macromol. 12:92-101.
    • (1990) Int. J. Biol. Macromol. , vol.12 , pp. 92-101
    • Fritzsche, K.1    Lenz, R.W.2    Fuller, R.C.3
  • 11
    • 0027933456 scopus 로고
    • Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: Evidence for a required posttranslational modification for catalytic activity
    • Gerngross, T. U., K. D. Snell, O. P. Peoples, A. J. Sinskey, E. Csuhai, S. Masamune, and J. Stubbe. 1994. Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 33:9311-9320.
    • (1994) Biochemistry , vol.33 , pp. 9311-9320
    • Gerngross, T.U.1    Snell, K.D.2    Peoples, O.P.3    Sinskey, A.J.4    Csuhai, E.5    Masamune, S.6    Stubbe, J.7
  • 12
    • 0002711454 scopus 로고
    • The importance of PHB-synthase substrate specificity in polyhydroxyalkanoate synthesis in Atcaligenes eutrophus
    • Haywood, G. W., A. J. Anderson, and E. A. Dawes. 1989. The importance of PHB-synthase substrate specificity in polyhydroxyalkanoate synthesis in Atcaligenes eutrophus. FEMS Microbiol. Lett. 57:1-6.
    • (1989) FEMS Microbiol. Lett. , vol.57 , pp. 1-6
    • Haywood, G.W.1    Anderson, A.J.2    Dawes, E.A.3
  • 13
    • 0017876460 scopus 로고
    • Recovery of poly-β-hydroxybutyrate from environmental sludge
    • Herron, J. S., J. D. King, and D. C. White. 1978. Recovery of poly-β-hydroxybutyrate from environmental sludge. Appl. Environ. Microbiol. 35:251-257.
    • (1978) Appl. Environ. Microbiol. , vol.35 , pp. 251-257
    • Herron, J.S.1    King, J.D.2    White, D.C.3
  • 14
    • 8944222327 scopus 로고    scopus 로고
    • 1981. European patent specification 0 0052 459.
    • Holmes, P. A., L. F. Wright, and S. H. Collins. 1981. European patent specification 0 0052 459.
    • Holmes, P.A.1    Wright, L.F.2    Collins, S.H.3
  • 15
    • 0025606149 scopus 로고
    • Molecular genetics of polyketides and its comparison to fatty acid biosynthesis
    • Hopwood, D. A., and D. H. Sherman. 1990. Molecular genetics of polyketides and its comparison to fatty acid biosynthesis. Annu. Rev. Genet. 24:37-66.
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 37-66
    • Hopwood, D.A.1    Sherman, D.H.2
  • 16
    • 0025170513 scopus 로고
    • Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin
    • Huber, M. L. B., J. W. Paschal, J. P. Leeds, H. A. Kirst, J. A. Wind, F. D. Miller, and J. R. Turner. 1990. Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. Antimicrob. Agents Chemother. 34:1535-1541.
    • (1990) Antimicrob. Agents Chemother. , vol.34 , pp. 1535-1541
    • Huber, M.L.B.1    Paschal, J.W.2    Leeds, J.P.3    Kirst, H.A.4    Wind, J.A.5    Miller, F.D.6    Turner, J.R.7
  • 17
    • 0026601481 scopus 로고
    • Pseudomonas putida KT2442 cultivated on glucose accumulates poly(3-hydroxyalkanoates) consisting of saturated and unsaturated monomers
    • Huijberts, G. N. M., G. Eggink, P. de Waard, G. W. Huisman, and B. Witholt. 1992. Pseudomonas putida KT2442 cultivated on glucose accumulates poly(3-hydroxyalkanoates) consisting of saturated and unsaturated monomers. Appl. Environ. Microbiol. 58:536-544.
    • (1992) Appl. Environ. Microbiol. , vol.58 , pp. 536-544
    • Huijberts, G.N.M.1    Eggink, G.2    De Waard, P.3    Huisman, G.W.4    Witholt, B.5
  • 18
    • 0027430939 scopus 로고
    • Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors
    • Joshi, A., and S. Smith. 1993. Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors. Biochem. J. 296:143-149.
    • (1993) Biochem. J. , vol.296 , pp. 143-149
    • Joshi, A.1    Smith, S.2
  • 19
    • 0027381395 scopus 로고
    • Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function
    • Joshi, A., and S. Smith. 1993. Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function. J. Biol. Chem. 268:22508-22513.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22508-22513
    • Joshi, A.1    Smith, S.2
  • 20
    • 0028556312 scopus 로고
    • Engineered synthesis of a triketide lactone from an incomplete modular polyketide synthase
    • Kao, C. M., G. L. Luo, L. Katz, D. E. Cane, and C. Khosla. 1994. Engineered synthesis of a triketide lactone from an incomplete modular polyketide synthase. J. Am. Chem. Soc. 116:11612-11613.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 11612-11613
    • Kao, C.M.1    Luo, G.L.2    Katz, L.3    Cane, D.E.4    Khosla, C.5
  • 22
    • 0016682083 scopus 로고
    • Malonyl and palmityl transferase-less mutants of the yeast fatty acid synthetase
    • Knobling, A., D. Schiffman, H.-D. Sickinger, and E. Schweizer. 1975. Malonyl and palmityl transferase-less mutants of the yeast fatty acid synthetase. Eur. J. Biochem. 56:359-364.
    • (1975) Eur. J. Biochem. , vol.56 , pp. 359-364
    • Knobling, A.1    Schiffman, D.2    Sickinger, H.-D.3    Schweizer, E.4
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
    • (1970) Nature (London) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 24
    • 0000862288 scopus 로고
    • Produit de déshydration et de polymérisation de l'acide β-oxybutyrique
    • Paris
    • Lemoigne, M. 1926. Produit de déshydration et de polymérisation de l'acide β-oxybutyrique. Bull. Soc. Chim. Biol. (Paris) 8:770-782.
    • (1926) Bull. Soc. Chim. Biol. , vol.8 , pp. 770-782
    • Lemoigne, M.1
  • 25
    • 0025977019 scopus 로고
    • Assembly of five bluetongue virus proteins expressed by recombinant baculoviruses: Inclusion of the largest protein VP1 in the core and virus-like particles
    • Loudon, P. T., and P. Roy. 1991. Assembly of five bluetongue virus proteins expressed by recombinant baculoviruses: inclusion of the largest protein VP1 in the core and virus-like particles. Virology 180:789-802.
    • (1991) Virology , vol.180 , pp. 789-802
    • Loudon, P.T.1    Roy, P.2
  • 27
    • 0028577728 scopus 로고
    • Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation
    • Nawrath, C., Y. Poirier, and C. Somerville. 1994. Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation. Proc. Natl. Acad. Sci. USA 91:12760-12764.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12760-12764
    • Nawrath, C.1    Poirier, Y.2    Somerville, C.3
  • 29
    • 0024445845 scopus 로고
    • Poly-β-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding β-ketothiolase and acetoacetyl-CoA reductase
    • Peoples, O. P., and A. J. Sinskey. 1989. Poly-β-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding β-ketothiolase and acetoacetyl-CoA reductase. J. Biol. Chem. 264:15293-15297.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15293-15297
    • Peoples, O.P.1    Sinskey, A.J.2
  • 30
    • 0024425823 scopus 로고
    • Poly-β-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC)
    • Peoples, O. P., and A. J. Sinskey. 1989. Poly-β-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC). J. Biol. Chem. 264:15298-15303.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15298-15303
    • Peoples, O.P.1    Sinskey, A.J.2
  • 31
    • 0026848971 scopus 로고
    • Poly-β-hydroxybutyrate, a biodegradable thermoplastic, produced in transgenic plants
    • Poirier, Y., D. E. Dennis, K. Klomparens, and C. Somerville. 1992. Poly-β-hydroxybutyrate, a biodegradable thermoplastic, produced in transgenic plants. Science 256:520-523.
    • (1992) Science , vol.256 , pp. 520-523
    • Poirier, Y.1    Dennis, D.E.2    Klomparens, K.3    Somerville, C.4
  • 32
    • 0028891191 scopus 로고
    • Production of polyhydroxyalkanoates, a family of biodegradable plastics and elastomers, in bacteria and plants
    • Poirier, Y., C. Nawrath, and C. Somerville. 1995. Production of polyhydroxyalkanoates, a family of biodegradable plastics and elastomers, in bacteria and plants. Bio/Technology 13:142-150.
    • (1995) Bio/Technology , vol.13 , pp. 142-150
    • Poirier, Y.1    Nawrath, C.2    Somerville, C.3
  • 33
    • 0025934140 scopus 로고
    • Isolation of a functional transferase component from the rat fatty acid synthase by limited trypsinization of the subunit monomer
    • Rangan, V. S., A. Witkowski, and S. Smith. 1991. Isolation of a functional transferase component from the rat fatty acid synthase by limited trypsinization of the subunit monomer. J. Biol. Chem. 266:19180-19185.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19180-19185
    • Rangan, V.S.1    Witkowski, A.2    Smith, S.3
  • 34
    • 33846455208 scopus 로고
    • Gas chromatographic determination of poly-β-hydroxybutyric acid in microbial biomass after hydrochloric acid propanolysis
    • Riis, V., and W. Mai. 1988. Gas chromatographic determination of poly-β-hydroxybutyric acid in microbial biomass after hydrochloric acid propanolysis. J. Chromatogr. 445:285-289.
    • (1988) J. Chromatogr. , vol.445 , pp. 285-289
    • Riis, V.1    Mai, W.2
  • 35
    • 37049104025 scopus 로고
    • Stereochemical course of dehydration catalyzed by yeast fatty acid synthase
    • Sedgwick, B., C. Morris, and S. J. French. 1978. Stereochemical course of dehydration catalyzed by yeast fatty acid synthase. Chem. Commun. (J. Chem. Soc. Sect. D) 1978:193-194.
    • (1978) Chem. Commun. (J. Chem. Soc. Sect. D) , vol.1978 , pp. 193-194
    • Sedgwick, B.1    Morris, C.2    French, S.J.3
  • 36
    • 0028557012 scopus 로고
    • The animal fatty acid synthase: One gene, one polypeptide, seven enzymes
    • Smith, S. 1994. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J. 8:1248-1259.
    • (1994) FASEB J. , vol.8 , pp. 1248-1259
    • Smith, S.1
  • 37
    • 0017116282 scopus 로고
    • Specific release of the thioesterase component of the fatty acid synthetase multienzyme complex by limited trypsinization
    • Smith, S., E. Agradi, L. Libertini, and K. N. Dileepan. 1976. Specific release of the thioesterase component of the fatty acid synthetase multienzyme complex by limited trypsinization. Proc. Natl. Acad. Sci. USA 73:1184-1188.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 1184-1188
    • Smith, S.1    Agradi, E.2    Libertini, L.3    Dileepan, K.N.4
  • 38
    • 0028837014 scopus 로고
    • Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis
    • Stachelhaus, T., and M. Marahiel. 1995. Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis. FEMS Microbiol. Lett. 125:3-14.
    • (1995) FEMS Microbiol. Lett. , vol.125 , pp. 3-14
    • Stachelhaus, T.1    Marahiel, M.2
  • 39
    • 0000829790 scopus 로고
    • Polyhydroxyalkanoic acids
    • D. Byrom (ed.), MacMillan Publishers Ltd., Basingstoke, United Kingdom
    • Steinbüchel, A. 1991. Polyhydroxyalkanoic acids, p. 123-213. In D. Byrom (ed.), Biomaterials: novel biomaterials from biological sources. MacMillan Publishers Ltd., Basingstoke, United Kingdom.
    • (1991) Biomaterials: Novel Biomaterials from Biological Sources , pp. 123-213
    • Steinbüchel, A.1
  • 40
    • 0026033649 scopus 로고
    • Physiology and molecular genetics of poly(beta-hydroxy-alkanoic acid) synthesis in Alcaligenes eutrophus
    • Steinbüchel, A., and H. G. Schlegel. 1991. Physiology and molecular genetics of poly(beta-hydroxy-alkanoic acid) synthesis in Alcaligenes eutrophus. Mol. Microbiol. 5:535-542.
    • (1991) Mol. Microbiol. , vol.5 , pp. 535-542
    • Steinbüchel, A.1    Schlegel, H.G.2
  • 41
    • 0029018968 scopus 로고
    • Diversity of bacterial polyhydroxyalkanoic acids
    • Steinbüchel, A., and H. E. Valentin. 1995. Diversity of bacterial polyhydroxyalkanoic acids. FEMS Microbiol. Lett. 128:219-228.
    • (1995) FEMS Microbiol. Lett. , vol.128 , pp. 219-228
    • Steinbüchel, A.1    Valentin, H.E.2
  • 43
    • 0002742232 scopus 로고
    • Bacterial metabolism of poly-β-hydroxybutyrate
    • D. Leeon, F. Stratman, and R. Zahlten (ed.). Elsevier Press, Amsterdam
    • Tomita, K., T. Saito, and T. Fukui. 1983. Bacterial metabolism of poly-β-hydroxybutyrate, p. 353-366. In D. Leeon, F. Stratman, and R. Zahlten (ed.). Biochemistry of metabolic processes. Elsevier Press, Amsterdam.
    • (1983) Biochemistry of Metabolic Processes , pp. 353-366
    • Tomita, K.1    Saito, T.2    Fukui, T.3
  • 44
    • 0023698950 scopus 로고
    • Isolation and mapping of the β-hydroxyacyl dehydratase activity of chicken liver fatty acid synthase
    • Tsukamoto, Y., and S, Wakil. 1988. Isolation and mapping of the β-hydroxyacyl dehydratase activity of chicken liver fatty acid synthase. J. Biol. Chem. 263:16225-16229.
    • (1988) J. Biol. Chem. , vol.263 , pp. 16225-16229
    • Tsukamoto, Y.1    Wakil, S.2
  • 45
    • 0026543269 scopus 로고
    • Identification of 4-hydroxyvaleric acid as a constituent in biosynthetic polyhydroxyalkanoic acids from bacteria
    • Valentin, H. E., A. Schönebaum, and A. Steinbüchel. 1992. Identification of 4-hydroxyvaleric acid as a constituent in biosynthetic polyhydroxyalkanoic acids from bacteria. Appl. Microbiol. Biotechnol. 36:507-514.
    • (1992) Appl. Microbiol. Biotechnol. , vol.36 , pp. 507-514
    • Valentin, H.E.1    Schönebaum, A.2    Steinbüchel, A.3
  • 46
    • 0011892215 scopus 로고
    • Studies on the mechanism of fatty acid synthesis
    • Wakil, S. J., and R. Bressler. 1962. Studies on the mechanism of fatty acid synthesis. J. Biol. Chem. 237:687-693.
    • (1962) J. Biol. Chem. , vol.237 , pp. 687-693
    • Wakil, S.J.1    Bressler, R.2
  • 47
    • 0016068411 scopus 로고
    • Poly-β-hydroxyalkanoate from activated sludge
    • Wallen, L. L., and W. K. Rohwedder. 1974. Poly-β-hydroxyalkanoate from activated sludge. Environ. Sci. Technol. 8:576-579.
    • (1974) Environ. Sci. Technol. , vol.8 , pp. 576-579
    • Wallen, L.L.1    Rohwedder, W.K.2
  • 48
    • 0030110779 scopus 로고    scopus 로고
    • Expression and analysis of a bacterial poly(hydroxyalkanoate) synthase in insect cells using a baculovirus system
    • Williams, M. D., A. M. Fieno, R. A. Grant, and D. H. Sherman. 1996. Expression and analysis of a bacterial poly(hydroxyalkanoate) synthase in insect cells using a baculovirus system. Protein Expr. Purif. 7:203-211.
    • (1996) Protein Expr. Purif. , vol.7 , pp. 203-211
    • Williams, M.D.1    Fieno, A.M.2    Grant, R.A.3    Sherman, D.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.