High-resolution NMR of an antisense DNA·RNA hybrid containing alternating chirally pure R(p) methylphosphonates in the DNA backbone

Biochemistry

Volumn 36, Issue 9, 1997, Pages 2371-2379

  Mujeeb, Anwer ^a,b   Reynolds, Mark A ^c,d   James, Thomas L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Genta Inc   (United States)

^d Sirna Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPHOSPHONIC ACID; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; CHROMOSOME HIGH RESOLUTION BANDING ANALYSIS; DNA RNA HYBRIDIZATION; MATHEMATICAL COMPUTING; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

BASE COMPOSITION; DNA, ANTISENSE; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; ORGANOPHOSPHORUS COMPOUNDS; PROTONS; RNA, ANTISENSE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031026112     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963008n     Document Type: Article

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