An efficient method for α-monofluorination of carbonyl compounds with molecular fluorine: Use of α-hydroxymethylene substituent as directing and activating groups

Tetrahedron Letters

Volumn 38, Issue 4, 1997, Pages 587-590

  Kamaya, Hiroshi ^a   Sato, Masayuki ^a   Kaneko, Chikara ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; FLUORINE;

ARTICLE; CHEMICAL REACTION; CRYSTALLIZATION; DRUG SYNTHESIS; FLUORINATION; REACTION ANALYSIS;

EID: 0031023038     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02378-7     Document Type: Article

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24. -1.
25. 1H NMR spectra.
26. -1.
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28. 4Cl solution, dried over anhydrous magnesium sulfate, and evaporated. Distillation of the residue gave 4b (378 mg, 84%) as a colorless oil of bp 76 °C (4 Torr).