Antiviral effects of 6-diazo-5-oxo-L-norleucin on replication of herpes simplex virus type 1

Antiviral Research

Volumn 33, Issue 3, 1997, Pages 165-175

  Cinatl, Jindrich ^a   Vogel, Jens U ^a   Cinatl, Jaroslav ^a   Kabickova, Hana ^b   Kornhuber, Bernhard ^a   Doerr, Hans W ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Clinical Laboratories   (Czech Republic)

Author keywords

6 Diazo 5 oxo L norleucin; Acyclovir; HSV; Virus resistance

Indexed keywords

6 DIAZO 5 OXONORLEUCINE; GLUTAMINE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; VERO CELL; VIRUS REPLICATION;

EID: 0031020102     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(96)01012-1     Document Type: Article

References (41)

1. Ahluwalia, G.S., Grey, J.L., Ham, Z. and Cooney, D.A. (1990) Metabolism and action of amino acid analog anti-cancer agents. Pharmacol. Ther. 46, 243-271.
2. Balan, P., Davis-Poynter, N., Bell, S., Atkinson, H., Browne, H. and Minson T. (1994) An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoprotein gC, gE, gI or the putative gJ. J. Gen. Virol. 75, 1245-1258.
3. Campadelli-Fiume, G., Farabegoli, F., Di Gaeta, S. and Roizman, B. (1991) Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1. J. Virol. 65, 1589-1595.
4. Cheung, P, Banfield, B.W. and Tufaro, F. (1991) Brefeldin A arrests the maturation and egress of herpes simplex virus particles during infection. J. Virol. 65, 1893-1904.
5. Cinatl, J.Jr., Cinatl J., Rabenau, H., Kornhuber, B. and Doerr, H.W. (1992a) HeLa cells grown continuously in protein-free medium: A novel model for the study of virus replication. Intervirology 33, 41-48.
6. Cinatl, J.Jr., Cinatl, J., Rabenau, H., Mainke, M., Kornhuber, B. and Doerr, H.W. (1992b) Effect of aciclovir on the replication of herpes simplex virus type 1 in MA-104 cell line resistant to aciclovir. Arzneim.-Forsch. Drug Res. 42, 977-980.
7. Cinatl, J.Jr., Cinatl, J., Radsak, K., Rabenau, H., Weber, B., Novak, M., Benda, R., Kornhuber, B. and Doerr, H.W. (1994) Replication of human cytomegalovirus in a rhabdomyosarcoma cell line depends on the state of differentiation of the cells. Arch. Virol. 138, 391-401.
8. Compton, T. and Courtney, R.J. (1984) Virus-specific glycoproteins associated with the nuclear fraction of herpes simplex virus infected cells. J. Virol. 49, 594-597.
9. Courtney, R.J., McCombs, R.M. and Benyesh-Melnick, M. (1970) Antigens specified by herpesviruses. I. Effect of arginine deprivation on antigen synthesis. Virology 40, 379-386.
10. Dingwell, K.S., Doering, L.C. and Johnson, D.C. (1995) Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virus. J. Virol. 69, 7078-7098.
11. Earhart, R.H., Amato, D.J., Chang, A.Y., Borden, E.C., Shiraki, M., Dowd, M.E., Comis, R.L., Davis, T.E. and Smith, T.J. (1990) Phase II trial of 6-diazo-5-oxo-L-norleucine versus aclacinomycin A in advanced sarcomas and mesotheliomas. Invest. New Drugs 8, 113-119.
12. Ehrlich, J., Coffey, G.L., Fisher, M.W., Hillegas, A.B., Kohberger, D.L., Machamer, H.E., Rightsel, W.A. and Roegenr, F.R. (1956) 6-Diazo-5-oxo-L-norleucine, a new tumor inhibitory substance. I. Biologic studies. Antibiot. Chemother. 6, 487-497.
13. Forrester, A., Farrell, H., Wilkinson, G., Kaye, J., Davis-Poynter, N. and Minson, T. (1992) Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. J. Virol. 66, 341-348.
14. Gershon, A.A., Sherman, D.L., Zhu, Z., Gabel, C.A., Ambron, R.T. and Gershon, M.D. (1994) Intracellular transport on newly synthesized varicella-zoster virus: envelopment in the transGolgi network. J. Virol. 68, 6372-6390.
15. Gloger, I., Arad, G. and Panet, A. (1985) Regulation of Moloney murine leukemia virus replication in chronically infected cells arrested at the G0/G1 phase. J. Virol. 54, 844-850.
16. Goldstein, G. and Guskey, L.E. (1984) Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxonorleucine or 2-deoxy-D-glucose. J. Med. Virol. 14, 159-167.
17. Hartman, S.C. and McGrath, T.F. (1973) Glutaminase A of Escherichia coli; reaction with the substrate analogue, 6-diazo-5-oxonorleucine. J. Biol. Chem. 248, 8506-8510.
18. Hirayama, N., Senda, M., Kurata K., Yoshikawa, Y. and Yamanouchi, K. (1985) Requirement of methionine for the replication of canine distemper virus in Vero cells. J. Gen. Virol. 66, 149-157.
19. Huang, R.C, Panin M., Romito, R.R. and Huang, Y.T. (1994) Inhibition of replication of human respiratory syncytial virus by 6-diazo-5-oxo-L-norleucine. Antiviral Res. 25, 269-279.
20. Hutchinson, L. and Johnson, D.C. (1955) Herpes simplex virus glycoprotein K promotes egeress of virus particles. J. Virol. 69, 5401-5413.
21. Inglis, V.B.M. (1968) Requirement of arginine for the replication of herpes virus. J. Gen. Virol. 3, 9-17.
22. Inuma, M., Maeno, K. and Matumoto, T. (1973) Studies on the assembly of Newcastle disease virus: an argine-dependent step in virus replication. Virology 51, 205-215.
23. Ito, Y., Kimura, Y., Nagata, Y. and Kunii, A. (1974) Effects of L-glutamine deprivation on growth of HVJ (Sendai virus) in BHK cells. J. Virol. 13, 557-566.
24. Ito, Y., Okazaki, H., Sakuma, S., Homma, M. and Ishida, N. (1969) Specific requirement of serine for the growth of Newcastle disease virus. Virology 39, 277-285.
25. Johnson, D.C. and Spear, P.G. (1982) Monensin inhibits the processing of herpes simplex glycoproteins, their transport to the cell surface, and the egress of virions from infected cells. J. Virol. 43, 1102-1112.
26. Keast, D. and Vasquez, A.R. (1992) Inhibition in vitro of the replication of murine cytomegalovirus or reovirus type 3 by the glutamine analogue acivicin. Arch. Virol. 124, 235-244.
27. King, G., Bounous, C. and Holmes, E. (1978) Human placental amidophosphoribosyl-transferase: comparison of the kinetics of glutamine and ammonia utilization. J. Biol. Chem. 253, 3933-3938.
28. Knipe, D.M. (1996) Virus-host cell interaction. In: B.N. Fields, D.M. Knipe, P.M. Howley, R. Chanock, J.L. Melnick, T.P. Monath, B. Roizman, S.E. Straus (Eds), Fields Virology, Vol.1, pp. 273-299, Lippincot-Raven, Philadelphia.
29. Levine, S., Buthala, D.A. and Hamilton, R.D. (1971) Late stage synchronization of respiratory syncytial virus replication. Virology 45, 390-400.
30. Ligas, M.W. and Johnson, D.C. (1988) A herpes simplex virus mutant in which glycoprotein D sequences are replaced by β-galactosidase sequences binds to but is unable to penetrate into cells. J. Virol. 62, 1486-1494.
31. Loh, P.C. and Oie, H.K. (1969) Role of lysine in the replication of reovirus. I. Synthesis of complete and empty virions. J. Virol. 4, 890-895.
32. Nishio, M., Tsurudome, M., Bando, H., Komada, H. and Yto, Y. (1990) Antiviral effects of 6-diazo-5-oxo-L-norleucine, antagonist of gamma-glutamyl transpeptidase, on the replication of human parainfluenza virus type 2. J. Gen. Virol. 71, 61-67.
33. Novogrodsky, A., Tate, S.S. and Meister, A. (1977) Uptake and utilization of L-glutamine by human lymphoid cells; relationship to gamma-glutamyl transpeptidase activity. Biochem. Biophys. Res. Commun. 78, 222-229.
34. Reed, L.I. and Muench, H. (1938). A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27, 493-497.
35. Rouse, H.C. and Schlesinger, R.W. (1967) An arginine-dependent step in the maturation of type 2 adenovirus. Virology 33, 513-522.
36. Spring, S.B., Roizman, B. and Spear, P.G. (1969) Selective failure of protein synthesis in herpes-infected cells deprived of arginine. Virology 38, 710-712.
37. Tankersley, R.W. (1964) Amino acid requirements of herpes simplex virus in human cells. J. Bacteriol. 87, 609-613.
38. Torrisi, M.R., Di Lazzara, C., Pavan, A., Pereira, L. and Campadelli-Fiume, G. (1992) Herpes simplex virus envelopment and maturation studied by fracture label. J. Virol 66, 554-561.
39. Wachsman, M., Hamzeh, F.M., Assadi, N.B., and Lietman, P.S. (1996) Antiviral activity of inhibitors of pyrimidine de-novo biosynthesis. Antiviral Chem. Chemother. 7, 7-13.
40. Weber, G. (1983) Biochemical strategy of cancer cells and the design of chemotherapy: G.H.A. Clowes memorial lecture. Cancer Res. 43, 3466-3492.
41. Whealy, ME., Card, J.P., Meade, R.P., Robbins AK. and Enquist, L.W. (1991) Effect of brefeldin A on alphaherpesvirus membrane protein glycolysation and virus egress. J. Virol. 65, 1066-1081.