Characterization of two temperature-sensitive mutants of coronavirus mouse hepatitis virus strain A59 with maturation defects in the spike protein

Journal of Virology

Volumn 71, Issue 2, 1997, Pages 949-955

  Luytjes, Willem ^a   Gerritsma, Heleen ^a   Bos, Evelyne ^a   Spaan, Willy ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA SYNTHESIS; TEMPERATURE SENSITIVITY; VIRION; VIRUS STRAIN;

EID: 0031015207     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.2.949-955.1997     Document Type: Article

References (39)

1. Bos, E. C. W., L. Heijnen, W. Luytjes, and W. J. M. Spaan. 1995. Mutational analysis of the murine coronavirus spike protein: effeet on cell-to-cell fusion. Virology 214:453-463.
2. Bos, E. C. W., W. Luytjes, H. Van der Meulen, H. K. Koerten, and W. J. M. Spaan. 1996. The production of recombinant infectious DI-particles of a murine coronavirus in the absence of helper virus. Virology 218:52-60.
3. Carleton, M., and D. T. Brown. 1996. Events in the endopiasmic reticulum abrogate the temperature sensitivity of Sindbis virus mutant ts23. J. Virol. 70:952-959.
4. Cavanagh, D. 1995. The coronavirus surface glycoprotein, p. 73-113. In S. G. Siddell (ed.), The Coronaviridae. Plenum Press, New York, N.Y.
5. De Groot, R. J., R. W. Van Leen, M. J. M. Dalderup, H. Vennema, M. C. Hprzinek, and W. J. M. Spaan. 1989. Stably expressed FIPV peplomer protein induces cell fusion and elicits neutralizing antibodies in mice. Virology 171:493-502.
6. Delmas, B., and H. Laude. 1990. Assembly of coronavirus spike protein into trimers and its role in epitope expression. J. Virol. 64:5367-5375.
7. Doms, R. W., R. A. Lamb, J. K. Rose, and A. Helenius. 1993. Folding and assembly of viral membrane proteins. Virology 193:545-562.
8. Fu, K., and R. S. Baric. 1994. Map locations of mouse hepatitis virus temperature-sensitive mutants: conformation of variable rates of recombination. J. Virol. 68:7458-7466.
9. Helenius, A., T. Marquardt, and I. Braakman. 1992. The endopiasmic reticulum as a protein-folding compartment. Trends Cell Biol. 2:227-231.
10. Holmes, K. V., E. W. Doller, and L. S. Sturman. 1981. Tunicamycin resistant glycosylation of coronavirus glycoprotein: demonstration of a novel type of viral glycoprotein. Virology 115:334-344.
11. Koetzner, C. A., M. M. Parker, C. S. Ricard, L. S. Sturman, and P. S. Masters. 1992. Repair and mutagenesis of the genome of a deletion mutant of the coronavirus mouse hepatitis virus by targeted RNA recombination. J. Virol. 66:1841-1848.
12. Koolen, M. J., A. D. Osterhaus, G. Van Steenis, M. C. Horzinek, and B. A. Van der Zeijst. 1983. Temperature-sensitive mutants of mouse hepatitis virus strain A59: isolation, characterization and neuropathogenic properties. Virology 125:393-402.
13. Krijnse Locker, J., M. Ericsson, P. J. Rottier, and G. Griffiths. 1994. Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step. J. Cell Biol. 124:55-70.
14. LaFay, F. 1974. Envelope proteins of vesicular stomatitis virus: effect of temperature-sensitive mutations in complementation groups 11 and V. J. Virol. 14:1220-1228.
15. Laude, H., and P. S. Masters. 1995. The coronavirus nucleocapsid protein, p. 141-179. In S. G. Siddell (ed.), The Coronaviridae. Plenum Press, New York, N.Y.
16. Lefkowitz, E. J., Pattnaik, A. K., and L. A. Ball. 1990. Complementation of a vesicular stomatitis virus glycoprotein G mutant with wild-type protein expressed from either a bovine papilloma virus or a vaccinia virus vector system. Virology 178:373-383.
17. Luytjes, W., H. Gerritsma, and W. J. M. Spaan. 1996. Replication of synthetic defective interfering RNAs derived from coronavirus mouse hepatitis virus-A59. Virology 216:174-183.
18. McIntosh, K. 1996. Coronaviruses, p. 1095-1133. In B. N. Fields, D. M. Knipe, P. M. Howley, et al. (ed.), Fields virology. Lippincott-Raven, Philadelphia, Pa.
19. Mebatsion, T., M. König, and K.-K. Conzelmann. 1996. Budding of rabies virus particles in the absence of the spike glycoprotein. Cell 84:941-951.
20. Metsikkö, K., and K. Simons. 1986. The budding mechanism of spikeless vesicular stomatitis virus particles. EMBO J. 5:1913-1920.
21. Opstelten, D. J. 1995. Envelope glycoprotein interactions in coronavirus assembly. Thesis. State University Utrecht, Utrecht, The Netherlands.
22. Opstelten, D. J., P. De Groote, M. C. Horzinek, H. Vennema, and P. J. Rottier. 1993. Disulfide bonds in folding and transport of mouse hepatitis coronavirus glycoproteins. J. Virol. 67:7394-7401.
23. Opstelten, D. J., M. J. Raamsman, K. Wolfs, M. C. Horzinek, and P. J. Rottier. 1995. Envelope glycoprotein interactions in coronavirus assembly. J. Cell Biol. 131:339-349.
24. Peng, D., C. A. Koetzner, and P. S. Masters. 1995. Analysis of second-site revertants of a murine coronavirus nucleocapsid protein deletion mutant and construction of nucleocapsid protein mutants by targeted RNA recombination. J. Virol. 69:3449-3457.
25. Peng, D., C. A. Koetzner, T. McMahon, Y. Zhu, and P. S. Masters. 1995. Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins. J. Virol. 69:5475-5484.
26. Ricard, C. S., C. A. Koetzner, L. S. Sturman, and P. S. Masters. 1996. A conditional-lethal murine coronavirus mutant that tails to incorporate the spike glycoprotein into assembled virions. Virus Res. 39:261-276.
27. Rothman, J. E., and F. T. Wieland. 1996. Protein sorting by transport vesicles. Science 272:227-234.
28. Rottier, P. J. M. 1995. The coronavirus membrane protein, p. 115-139. In S. G. Siddell (ed.), The Coronaviridae. Plenum Press, New York, N.Y.
29. Rottier, P. J., M. C. Horzinek, and B. A. Van der Zeijst. 1981. Viral protein synthesis in mouse hepatitis virus strain A59-infected cells: effect of tunicamycin. J. Virol. 40:350-357.
30. Sambrook, J., L. Rodgers, J. White, and M. J. Gething. 1985. Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin. EMBO J. 4:91-103.
31. Siddell, S. G. 1995. The small-membrane protein, p. 181-189. In S. G. Siddell (ed.), The Coronaviridae. Plenum Press, New York, N.Y.
32. Spaan, W. J. M., P. J. Rottier, M. C. Horzinek, and B. A. M. Van der Zeijst. 1981. Isolation and identification of virus-specific mRNAs in cells infected with mouse hepatitis virus (MHV-A59). Virology 108:424-434.
33. Sturman, L. S., and K. V. Holmes. 1985. The novel glycoproteins of coronaviruses. Trends Biochem. Sci. 10:17-20.
34. Tooze, J., S. Tooze, and G. Warren. 1984. Replication of coronavirus MHV-A59 in sac-cells: determination of the first site of budding of progeny virions. Eur. J. Cell Biol. 33:281-293.
35. Van der Most, R. G., P. J. Bredenbeek, and W. J. Spaan. 1991. A domain at the 3′ end of the polymerase gene is essential for encapsidation of coronavirus defective interfering RNAs. J. Virol. 65:3219-3226.
36. Vennema, H., G. J. Godeke, J. W. A. Rossen, W. F. Voorhout, M. C. Horzinek, D. J. E. Opstelten, and P. J. M. Rottier. 1996. Nucleocapsid-independent assembly of coronavirus-like particles by co-expression of viral envelope protein genes. EMBO J. 15:2020-2028.
37. Vennema, H., P. J. M. Rottier, L. Heijnen, G. J. Godeke, M. C. Horzinek, and W. J. M. Spaan. 1990. Biosynthesis and function of the eoronavirus spike protein. Adv. Exp. Med. Biol. 276:9-19.
38. Whitt, M. A., P. Zagouras, B. Crise, and J. K. Rose. 1990. A fusion-defective mutant of the vesicular stomatitis virus glycoprotein. J. Virol. 64:4907-4913.
39. Whitt, M. A., L. Chong, and J. K. Rose. 1989. Glycoprotein cytoplasmic domain sequences required for rescue of a vesicular stomatitis virus glycoprotein mutant. J. Virol. 63:3569-3578.