P53 gene mutations in osteosarcomas in the dog

Cancer Letters

Volumn 111, Issue 1-2, 1997, Pages 173-178

  Van Leeuwen, I S ^a   Cornelisse, C J ^b   Misdorp, W ^a   Goedegebuure, S A ^a   Kirpensteijn, J ^a   Rutteman, G R ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Dog; Osteosarcoma; p53; Tumor suppressor gene

Indexed keywords

PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENE MUTATION; METASTASIS; MISSENSE MUTATION; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ANIMALS; BONE NEOPLASMS; DOG DISEASES; DOGS; GENES, P53; MUTATION; OSTEOSARCOMA; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

ANIMALIA; CANIS FAMILIARIS;

EID: 0031014338     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04529-6     Document Type: Article

References (22)

1. Greenblatt, M.S., Bennett, W.P., Hollstein, M. and Harris, C.C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis, Cancer Res., 54, 4855-4878.
2. Toguchida, J., Yamaguchi, T., Ritchie, B., Beauchamp, R.L., Dayton, S.H., Herrera, G.E., Yamamuro, T., Kotoura, Y., Sasaki, M.S., Little, J.B., Weichselbaum, R.R., Ishizaki, K.I. and Yandell, D.W. (1992) Mutation spectrum of the p53 gene in bone and soft tissue sarcomas, Cancer Res., 52, 6194-6199.
3. Smith-Sørensen, B., Gebhardt, M.C., Kloen, P., McIntyre, J., Aguilar, F., Cerutti, P. and Børresen, A.-L. (1993) Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE), Hum.Mutat, 2, 274-285.
4. Mousses, S., McAuley, L., Bell, R.S., Kandel, R. and Andrulis, I.L. (1996) Molecular and immunohistochemical identification of p53 alterations in bone and soft tissue sarcomas, Mod. Pathol., 9, 1-6.
5. Malkin, D., Li, P.P., Strong, L.C., Fraumeni, J.F. Jr., Nelson, C.E., Kim, D.H., Kassel, J., Gryka, M.A., Bischoff, F.Z., Tainsky, M.A. and Friend, S.H. (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms, Science, 250, 1233-1238.
6. Soussi, T., Caron de Fromentel, C. and May, P. (1990) Structural aspects of the p53 protein in relation to gene evolution, Oncogene, 5, 945-952.
7. Kraegel, S.A., Pazzi, K.A. and Madewell, B.R. (1995) Sequence analysis of canine p53 in the region of exons 3-8, Cancer Lett., 92, 181-186.
8. Van Leeuwen, I.S., Hellmén, E., Cornelisse, C.J., van den Burgh, B. and Rutteman, G.R. (1996) P53 mutations in mam-mary tumor cell lines and corresponding tumor tissues in the dog. Anticancer Res., in press.
9. Devilee, P., Van Leeuwen, I.S., Voesten, A., Rutteman, G.R., Vos, J.H. and Cornelisse, C.J. (1994) The canine p53 gene is subject to somatic mutations in thyroid carcinoma, Anticancer Res., 14, 2039-2046.
10. Withrow, S.J., Powers, B.E., Straw, R.C. and Williams, R. (1990) Comparative aspects of osteosarcoma: dog versus man, Clin. Orthop., 270, 159-167.
11. Misdorp, W. (1980) Animal model of human disease: skeletal osteosarcoma, Animal model: canine osteosarcoma. Am. J. Pathol., 98, 285-288.
12. MacEwen, E.G. (1990) Spontaneous tumors in dogs and cats: models for the study of cancer biology and treatment, Cancer Metastasis Rev., 9, 125-136.
13. Heyman, S.J., Diefenderfer, D.L., Goldschmidt, M.H. and Newton, C.D. (1992) Canine axial skeletal osteosarcoma: a retrospective study of 116 cases (1986-1989), Vet. Surg., 21, 304-310.
14. Misdorp, W. and Van Der Heul, R.O. (1976) Tumours of bones and joints in domestic animals, Bull. W. H. O., 56, 265-282.
15. Chomczynski, P. and Sacchi, N. (1987) Single step method of RNA isolation by acid-guanidium thiocyanate-phenolchloroform extraction, Anal. Biochem., 162, 156-159.
16. Orita, M., Suzuki, Y., Sekiya, T. and Hayashi, K. (1989) Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction, Genomics, 5, 874-879.
17. Davis, L.G., Dibner, M.D. and Battey, J.F. (Editors) (1986) Basic Methods in Molecular Biology. Elsevier, New York.
18. Donehower, L.A., Harvey, M., Slagle, B.L., McArthur, M.J., Montgomery, C.A. Jr., Butel, J.S. and Bradley, A. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours, Nature, 356, 215-221.
19. Jego, N., Thomas, G. and Hamelin, R. (1993) Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers, Oncogene, 8, 209-213.
20. Sagartz, J.E., Bodley, W.L., Gamblin, R.M., Couto, C.G., Tierney, L.A. and Capen, C.C. (1996) p53 tumor suppressor protein overexpression in osteogenic tumors of dogs, Vet. Pathol., 33, 213-221.
21. Leach, F.S., Tokino, T., Meltzer, P., Burrell, M., Oliner, J.D., Smith, S., Hill, D.E., Sidransky, D., Kinzler, K.W. and Vogelstein, B. (1993) p53 mutation and MDM2 amplification in human soft tissue sarcomas, Cancer Res., 53, 2231-2234.
22. Lamb, P. and Crawford, L. (1986) Characterization of the human p53 gene, Mol. Cell. Biol., 6, 1379-1385.