p53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog

Anticancer Research

Volumn 16, Issue 6 B, 1996, Pages 3737-3744

  Van Leeuwen, Irma S ^a   Hellmèn, Eva ^d   Cornelisse, Cees J ^c   Van Burgh, Bart Den ^b   Rutteman, Gerard R ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b HUBRECHT INSTITUTE   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Dog; Mammary tumor cell lines; p53; Tumorigenesis

Indexed keywords

MUTANT PROTEIN; PROTEIN P53;

ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BREAST CARCINOGENESIS; BREAST METASTASIS; BREAST TUMOR; CODON; CONTROLLED STUDY; DNA PROBE; DNA SEQUENCE; DOG; GENE MUTATION; GENE REARRANGEMENT; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SOUTHERN BLOTTING; TUMOR;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA MUTATIONAL ANALYSIS; DOG DISEASES; DOGS; FEMALE; GENES, P53; MAMMARY NEOPLASMS, ANIMAL; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TUMOR CELLS, CULTURED;

EID: 0030515969     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Misdorp W: Histologic classification and further characterization of tumors in domestic animals. Adv Vet Sci Comp Med 20: 191-221, 1976.
2. MacEwen EG: Spontaneous tumors in dogs and cats: Models for the study of cancer biology and treatment. Cancer Met Rev 9: 125-36, 1990.
3. Cornelisse CJ, Rutteman GR, Kuipers-Dijkshoorn NJ, and Hellmén E: The difference in DNA ploidy patlern between some canine and human neoplasms appears to be genuine and a reflection of dissimilarities in DNA aneuploidy evolution. Anticancer Res 14: 1599-1602, 1994.
4. Hellmen E, Lindgren A, Linell F, Matsson P, and Nilsson A: Comparison of histology and clinical variables to DNA ploidy in canine mammary tumors. Vet Pathol 25: 219-226, 1988.
5. Rutteman GR, Cornelisse CJ, Dijkshoorn NJ, Poortman J and Misdorp W: Flow cytometric analysis of DNA ploidy in canine mammary tumors. Cancer Res 48: 3411-3417, 1988.
6. Perez Alenza MD, Rutteman GR, Kuipers-DUkshoorn NJ, Pena L, Montoya A, Misdorp W and Cornelisse CJ: DNA flow cytometry of canine mammary tumours: the relationship of DNA ploidy and S-phase fraction to clinical and histological features. Res Vet Sci 58: 238-243, 1995.
7. I.evine AJ, Momand J and Finlay CA: The p53 tumour suppressor gene. Nature 351: 453-456, 1991.
8. Lane DP: P53, guardian of the genome. Nature 358: 15-16, 1992.
9. Hollstein M, Sidransky D, Volgelstein B and Harris CC: P53 mutations in human cancers. Science (Washington DC) 253: 49-53, 1991.
10. Greenblatt MS, Bennett WP, Hollstein M and Harris CC: Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
11. Soussi T, Caron de Fromentel C and May P: Structural aspects of the p53 protein in relation to gene evolution. Oncogene 5: 945-952, 1990.
12. Vogelstein B and Kinzler KW: P53 function and dysfunction. Cell 70: 523-526, 1992.
13. Casey G, Lo-Hsueh M, Lopez ME, Vogelstein B and Stanbridge EJ: Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gen. Oncogene 6: 1791-1797, 1991.
14. Runnebaum IB, Yee J, Kieback DG, Sukumar S and Friedmann T: Wild-type p53 suppresses the malignant phenotype in breast cancer cells containing mutant p53 alleles. Anticancer Res 14: 1137-1144, 1994.
15. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery Jr CA, Butel JS and Bradley A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-221, 1992.
16. Purdie CA, Harrison DJ, Peter A, Dobbie L, White S, Howie SEM, Salter DM, Bird CC, Wyllie AH, Hooper ML and Clarke AR: Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene. Oncogene 9: 603-609, 1994
17. Donehower LA, Godley LA, Aldaz CM, Pyle R, Shi Y, Pinkel D, Gray J, Bradley A, Medina D and Varmus HE: Deficiency of p53 accelerates mammary tumorigenisis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Devel 9: 882-895, 1995.
18. Devilee P, Leeuwen van IS, Voesten A, Rutteman GR, Vos JH and Cornelisse CJ: The canine p53 gene is subject to somatic mutations in thyroid carcinoma. Anticancer Res 14: 2039-2046, 1994.
19. Hellmén E: Characterization of four in vitro established canine mammary carcinoma and one atypical benign mixed tumor cell lines. In Vitro Cell Dev Biol 28A: 309-319, 1992.
20. Van der Burg B, van Selm Miltenburg AJP, van Maurik P, Rutteman GR, Misdorp W, de Laat SW and van Zoelen EJJ: Isolation of autonomously growing mammary tumor cell lines cultured in medium supplemented with serum treated to inactivate growth factors. J Natl Cancer Inst 81: 1545-51, 1989.
21. Chomczynski P, and Sacchi N: Single step method of RNA isolation by acid-guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
22. Volkenandt M, Dicker AP, Fanin R, Banerjee D, Albino A and Bertino JR: Methods in Molecular Biology, vol. 15, PCR Protocols: Current Methods and Applications. Edited by: B.A. White. Humana Press Inc., Totowa, NJ, 1993.
23. Orita M, Suzuki Y, Sekiya T and Hayashi K: Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5: 874-879, 1989.
24. Davis LG, Dibner MD, Battey JF (eds.): Basic methods in Molecular Biology. Elsevier Science Publ Co, New York, 1986.
25. Caron de Frontentel C, and Soussi T: TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromosomes Cancer 4: 1-15, 1992.
26. Okuda M, Umeda A, Matsumoto Y, Momoi Y, Watari T, Goitsuka R, Obrien SJ, Tsujimoto H and Hasegawa A: Molecular cloning and chromosomal mapping of feline p53 tumor suppressor gene. J Vet Med Science 55: 801-805, 1993.
27. Bressac B, Kew M, Wands J, and Ozturk M: Selective G to T mutations of p53 genes in hepatocellular carcinoma from southern Africa. Nature (Lond.) 350: 429-431, 1991.
28. Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, and Ponten J: A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88: 10124-10128, 1991.
29. Kraegel SA, Pazzi KA, Madewell BR: Sequence analysis of canine p53 in the region of exons 3-8. Cancer Letters 92: 181-186, 1995.
30. Mayr B, Schellander K, Schleger W and Reifinger M: Sequence of an exon of the canine p53 gene - mutation in a papilloma. Br Vet J 150: 81-84, 1994.
31. Wright PA, Lemoine NR, Goretzki PE, Wyllie FS, Bond J, Hughes C, Roher H, Williams ED and Wynford-Thomas D: Mutation of the p53 gene in a differentiated human thyroid carcinoma cell line, but not in primary thyroid tumours. Oncogenc 6: 1693-1699, 1991.
32. Effert P, McCoy R, Abdel-Hamid M, Flynn K, Zhang O, Busson P, Tursz T, Liu E and RaabTraub N: Alterations of the p53 gene in nasopharyngeal carcinoma. J Virol 66: 3768-3775, 1992.
33. Azzopardi JG: Problems in breast pathogy vol 11, Major problems in pathology. Edited by: Bennington JL. WB Saunders Company Ltd, London, 1979, pp365-375
34. Hellmén E and Lindgren A: The expression of intermediate filaments in canine mammary glands and their tumors. Vet Pathol 26: 420-428, 1989.