메뉴 건너뛰기




Volumn 33, Issue 2, 1997, Pages 109-115

The role of genotypic heterogeneity in wild type virus populations on the selection of nonnucleoside reverse transcriptase inhibitor-resistant viruses

Author keywords

HIV 1; Resistance; Reverse transcriptase inhibitors

Indexed keywords

RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 0031014263     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(96)01008-X     Document Type: Article
Times cited : (7)

References (34)
  • 2
    • 0027381149 scopus 로고
    • Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives
    • Balzarini, J., Karlsson, A. and De Clercq, E. (1993a) Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives. Mol. Pharmacol. 44, 694-701.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 694-701
    • Balzarini, J.1    Karlsson, A.2    De Clercq, E.3
  • 3
    • 0027363224 scopus 로고
    • Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
    • Balzarini, J., Karlsson, A., Perez-Perez, M.J., Camarasa, M.J. and De Clercq, E. (1993b) Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus. Virology 196, 576-585.
    • (1993) Virology , vol.196 , pp. 576-585
    • Balzarini, J.1    Karlsson, A.2    Perez-Perez, M.J.3    Camarasa, M.J.4    De Clercq, E.5
  • 4
    • 0028285185 scopus 로고
    • Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C→C181I)RT HIV-1 mutants
    • Balzarini, J., Karlsson, A., Sardana, V.V., Emini, E.A., Camarasa, M.J. and De Clercq, E. (1994) Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C→C181I)RT HIV-1 mutants. Proc. Natl. Acad. Sci. USA 91, 6599-6603.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6599-6603
    • Balzarini, J.1    Karlsson, A.2    Sardana, V.V.3    Emini, E.A.4    Camarasa, M.J.5    De Clercq, E.6
  • 5
    • 0028940526 scopus 로고
    • Oxathiin carboxanilide derivatives: A class of nonnucleoside HIV-1-specific reverse transcriptase inhibitors (NNRTIs) that are active against mutant HIV-1 strains resistant to other NNRTIs
    • Balzarini, J., Jonckheere, H., Harrison, W.A., Dao, D.C., Anne, J., De Clercq, E. and Karlsson, A. (1995a) Oxathiin carboxanilide derivatives: a class of nonnucleoside HIV-1-specific reverse transcriptase inhibitors (NNRTIs) that are active against mutant HIV-1 strains resistant to other NNRTIs. Antiviral Chem. Chemother. 6, 169-178.
    • (1995) Antiviral Chem. Chemother. , vol.6 , pp. 169-178
    • Balzarini, J.1    Jonckheere, H.2    Harrison, W.A.3    Dao, D.C.4    Anne, J.5    De Clercq, E.6    Karlsson, A.7
  • 6
    • 0029079399 scopus 로고
    • Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives)
    • Balzarini, J., Perez-Perez, M.J., Velazquez, S., San-Felix, A., Camarasa, M.J., De Clercq, E. and Karlsson, A. (1995b) Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives). Proc. Natl. Acad. Sci. USA 92, 5470-5474.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5470-5474
    • Balzarini, J.1    Perez-Perez, M.J.2    Velazquez, S.3    San-Felix, A.4    Camarasa, M.J.5    De Clercq, E.6    Karlsson, A.7
  • 9
    • 0028899197 scopus 로고
    • Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups
    • Buckheit, R.W. Jr., Fliakas-Boltz, V., Decker, W.D., Roberson, J.L., Stup, T.L., Pyle, C.A., White, E.L., McMahon, J.B., Currens, M.J. and Boyd, M.R. et al. (1995a) Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups. Antiviral Res. 117-132.
    • (1995) Antiviral Res. , pp. 117-132
    • Buckheit R.W., Jr.1    Fliakas-Boltz, V.2    Decker, W.D.3    Roberson, J.L.4    Stup, T.L.5    Pyle, C.A.6    White, E.L.7    McMahon, J.B.8    Currens, M.J.9    Boyd, M.R.10
  • 10
    • 0029008106 scopus 로고
    • Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase
    • Buckheit, R.W. Jr., Fliakas-Boltz, V., Yeagy-Bargo, S., Weislow, O., Mayers, D.L., Boyer, P.L., Hughes, S.H., Pan, B.C., Chu, S.H. and Bader, J.P. (1995b) Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase. Virology 210, 186-193.
    • (1995) Virology , vol.210 , pp. 186-193
    • Buckheit R.W., Jr.1    Fliakas-Boltz, V.2    Yeagy-Bargo, S.3    Weislow, O.4    Mayers, D.L.5    Boyer, P.L.6    Hughes, S.H.7    Pan, B.C.8    Chu, S.H.9    Bader, J.P.10
  • 12
    • 0026333212 scopus 로고
    • Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcrip-tase
    • Cohen, K.A., Hopkins, J., Ingraham, R.H., Pargellis, C., Wu, J.C., Palladino, D.E., Kinkade, P., Warren, T.C., Rogers, S. and Adams, J. (1991) Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcrip-tase. J. Biol. Chem. 266, 14670-14674.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14670-14674
    • Cohen, K.A.1    Hopkins, J.2    Ingraham, R.H.3    Pargellis, C.4    Wu, J.C.5    Palladino, D.E.6    Kinkade, P.7    Warren, T.C.8    Rogers, S.9    Adams, J.10
  • 13
    • 0026638419 scopus 로고
    • Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors
    • Condra, J.H., Emini, E.A., Gotlib, L., Graham, D.J., Schlabach, A.J., Wolfgang, J.A., Colonno, R.J. and Sardana, V.V. (1992) Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors. Antimicrob. Agents Chemother. 36, 1441-1446.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 1441-1446
    • Condra, J.H.1    Emini, E.A.2    Gotlib, L.3    Graham, D.J.4    Schlabach, A.J.5    Wolfgang, J.A.6    Colonno, R.J.7    Sardana, V.V.8
  • 14
    • 0026721522 scopus 로고
    • Resistance to human immunodeficiency virus type I reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis
    • DeVreese, K., Debyser, Z., Vandamme, A.-M., Pauwels, R., Desmyter, J., De Clercq, E. and Anne, J. (1992) Resistance to human immunodeficiency virus type I reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis. Virology 900-904.
    • (1992) Virology , pp. 900-904
    • Devreese, K.1    Debyser, Z.2    Vandamme, A.-M.3    Pauwels, R.4    Desmyter, J.5    De Clercq, E.6    Anne, J.7
  • 16
    • 0024999452 scopus 로고
    • Retroviral reverse transcriptase: Synthesis, structure, and function
    • Goff, S.P. (1990) Retroviral reverse transcriptase: synthesis, structure, and function. J. Acquir. Immuno. Def. Syn. 3, 817-831.
    • (1990) J. Acquir. Immuno. Def. Syn. , vol.3 , pp. 817-831
    • Goff, S.P.1
  • 20
    • 0026647540 scopus 로고
    • The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum
    • published erratum appears in J. Med. Chem. 1993 Apr 16; 36(8):1110
    • Kashman, Y., Gustafson, K.R., Fuller, R.W., Cardellina, J.H., McMahon, J.B., Currens, M.J., Buckheit, R.W. Jr., Hughes, S.H., Cragg, G.M. and Boyd, M.R. (1992) The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum [published erratum appears in J. Med. Chem. 1993 Apr 16; 36(8):1110]. J. Med. Chem. 35, 2735-2743.
    • (1992) J. Med. Chem. , vol.35 , pp. 2735-2743
    • Kashman, Y.1    Gustafson, K.R.2    Fuller, R.W.3    Cardellina, J.H.4    McMahon, J.B.5    Currens, M.J.6    Buckheit R.W., Jr.7    Hughes, S.H.8    Cragg, G.M.9    Boyd, M.R.10
  • 21
    • 0029774789 scopus 로고    scopus 로고
    • Isolation and characterization of HIV-1 isolates resistant to oxathiin carboxanilide analogs: Evaluation of variables in the resistance selection process
    • Kinjerski, T.L., Pallansch, L.A. and Buckheit, R.W. Jr. (1996) Isolation and characterization of HIV-1 isolates resistant to oxathiin carboxanilide analogs: evaluation of variables in the resistance selection process. Antiviral Chem. Chemother. 7: 261-269.
    • (1996) Antiviral Chem. Chemother. , vol.7 , pp. 261-269
    • Kinjerski, T.L.1    Pallansch, L.A.2    Buckheit R.W., Jr.3
  • 23
    • 0026693137 scopus 로고
    • Crystal structure at 3.5 a resolution of HIV-1 reverse transcriptase complexed with an inhibitor
    • Kohlstaedt, L.A., Wang, J., Friedman, J.M., Rice, P.A. and Steitz, T.A. (1992) Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256, 1783-1790.
    • (1992) Science , vol.256 , pp. 1783-1790
    • Kohlstaedt, L.A.1    Wang, J.2    Friedman, J.M.3    Rice, P.A.4    Steitz, T.A.5
  • 24
    • 0029834002 scopus 로고    scopus 로고
    • Fluctuating diversity in the HTLV-IIIB virus stock: Implications for neutralization and challenge experiments
    • Lockey, T.D., Slobod, K.S., Rencher, S.D., Srinivas, R.V. and Hurwitz, J.L. (1996) Fluctuating diversity in the HTLV-IIIB virus stock: implications for neutralization and challenge experiments. AIDS Res. Hum. Retrov. 12, 1297-1299.
    • (1996) AIDS Res. Hum. Retrov. , vol.12 , pp. 1297-1299
    • Lockey, T.D.1    Slobod, K.S.2    Rencher, S.D.3    Srinivas, R.V.4    Hurwitz, J.L.5
  • 27
    • 0028855166 scopus 로고
    • Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
    • Mellors, J.W., Larder, B.A. and Schinazi, R.F. (1995) Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antiviral News 3, 8-13.
    • (1995) Int. Antiviral News , vol.3 , pp. 8-13
    • Mellors, J.W.1    Larder, B.A.2    Schinazi, R.F.3
  • 28
    • 0025679303 scopus 로고
    • Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor
    • published erratum appears in Science 1991 Jan 25; 251(4992):362
    • Merluzzi, V.J., Hargrave, K.D., Labadia, M., Grozinger, K., Skoog, M., Wu, J.C., Shih, C.K., Eckner, K., Hattox, S. and Adams, J. et al. (1990) Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor [published erratum appears in Science 1991 Jan 25; 251(4992):362]. Science 250, 1411-1413.
    • (1990) Science , vol.250 , pp. 1411-1413
    • Merluzzi, V.J.1    Hargrave, K.D.2    Labadia, M.3    Grozinger, K.4    Skoog, M.5    Wu, J.C.6    Shih, C.K.7    Eckner, K.8    Hattox, S.9    Adams, J.10
  • 29
    • 34250082672 scopus 로고
    • Review of HIV-1 reverse transcriptase three dimensional structure: Implications for drug design
    • Nanni, R.G., Ding, J., Jacobo-Molina, A., Hughes, S.H. and Arnold, E. (1993) Review of HIV-1 reverse transcriptase three dimensional structure: implications for drug design. Perspect. Drug Discovery Design 1, 129-150.
    • (1993) Perspect. Drug Discovery Design , vol.1 , pp. 129-150
    • Nanni, R.G.1    Ding, J.2    Jacobo-Molina, A.3    Hughes, S.H.4    Arnold, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.