V(H) gene use by HIV type 1-associated lymphoproliferations

AIDS Research and Human Retroviruses

Volumn 13, Issue 2, 1997, Pages 135-150

  Ng, Valerie L ^a,c   Hurt, Mark H ^a   Herndier, Brian G ^a   Fry, Kirk E ^b   McGrath, Michael S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Genelabs Incorporated   (United States)

^c SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPHOCYTE PROLIFERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VIRUS GENE; AMINO ACID SEQUENCE; B CELL LYMPHOMA; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING;

IMMUNOGLOBULIN HEAVY CHAIN; LEUKOCYTE ANTIGEN; VIRUS DNA;

AMINO ACID SEQUENCE; ANTIGENS, CD; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA, VIRAL; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOMA, AIDS-RELATED; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0031012633     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1997.13.135     Document Type: Article

References (57)

1. Pelicci P-G, Knowles DM, Zalmen AA, Wieczorek R, Luciw P, Dina D, Basilico C, and Dalla-Favera R: Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. J Exp Med 1986;164:2049-2076.
2. Knowles DM, Chamulak G, Subar M, Burke JS, Dugan M, Wernz J, Slywotzky C, Pelicci P-G, Dalla-Favera R, and Raphael B: Lymphoid neoplasia associated with the acquired immunodeficiency syndrome (AIDS). The New York University Medical Center experience with 105 patients. Ann Intern Med 1988; 108:744-753.
3. Shiramizu BT, Herndier BG, Meeker T, Kaplan L, and McGrath MS: Molecular and immunophenotypic characterization of AIDS-associated Epstein-Barr virus-negative polyclonal lymphoma. J Clin Oncol 1992;10:383-389.
4. Ballerini P, Gaidano G, Gong J, Tassi V, Saglio G, Knowles D, and Dalla-Favera R: Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. Blood 1993;81:166-176.
5. Shibata D, Weiss L, Hernandez A, Nathwani B, Bernstein L, and Levine AM: Epstein-Barr virus-associated non-Hodgkin's lymphoma in patients infected with the human immunodeficiency virus. Blood 1993;81:2102-2109.
6. Delecluse HJ, Raphael M, Magaud JP, Felman P (the French Study Group of Pathology for HIV-associated tumors), Abd Alsamad I, Bornkamm GW, and Lenoir GM: Variable morphology of human immunodeficiency virus-associated lymphomas with c-myc rearrangements. Blood 1993;82:552-563.
7. McGrath MS, Shiramizu BT, Meeker T, Kaplan L, and Herndier BG: EBV negative polyclonal lymphoma: Identification of a new HIV-associated disease process. J Acquir Immune Defic Syndr 1991;4:408-415.
8. Meeker TC, Shiramizu BT, Kaplan L, Herndier BG, Sanchez H, Grimaldi JC, Baumgartner J, Rachlin J, Feigal E, Rosenblum M, and McGrath MS: Evidence for molecular subtypes of HIV-1 associated lymphoma: Division into peripheral monoclonal lymphoma, peripheral polyclonal lymphoma and central nervous system lymphoma. AIDS 1991;5:669-674.
9. Marsh JW, Herndier B, Tsuzuki A, Ng VL, Shiramizu B, Abbey N, and McGrath MS: Cytokine expression in AIDS associated large cell lymphoma. J Interferon Cytokine Res 1995;15:261-268.
10. Herndier BG, Kaplan LD, and McGrath MS: Pathogenesis of AIDS lymphomas. AIDS 1994;8:1025-1049.
11. H-gene putative somatic mutation analysis. Blood 1994;83:1067-1078.
12. H4-21 segments. Blood 1994;83:2952-2961.
13. H gene segment over-represented in the autoimmune repertoire. Arthr Rheum 1992; 35:11-18.
14. Kocks C and Rajewsky K: Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways. Annu Rev Immunol 1989;7:537-559.
15. Andris JS, Johnson S, Zolla-Pazner S, and Capra JD: Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune resopnse. Proc Natl Acad Sci USA 1991;88:7783-7787.
16. Moran MJ, Andris JS, Matsumato Y-I, Capra JD, and Hersh EM: Variable region genes of anti-HIV human monoclonal antibodies: Non-restricted use of the V gene repertoire and extensive somatic mutation. Mol Immunol 1993;30:1543-1551.
17. van der Donk EMM, Schutten M, Osterhaus ADME, and van der Heijden RWJ: Molecular characterization of variable heavy and light chain regions of five HIV type 1-specific human monoclonal antibodies. AIDS Res Hum Retroviruses 1994;10:1639-1649.
18. Sambrook J, Fritsch E, and Maniatis T: Molecular Cloning, 2nd Ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1989.
19. Dambaugh T, Beisel C, Hummel M, King W, Fennewald S, Cheung A, Heller M, Raab-Traub N, and Kieff E: Epstein-Barr virus (B95-8) DNA VII: Molecular cloning and detailed mapping. Proc Natl Acad Sci USA 1980;77:2999-3003.
20. Ravetch JV, Siebenlist U, Korsmeyer S, Waldmann T, and Leder P: Structure of the human immunoglobulin mu locus: Characterization of embryonic and rearranged J and D genes. Cell 1981;27:583-591.
21. Battey J, Moulding C, Taub R, Murphy W, Stewart T, Potter H, Lenoir G, and Leder P: The human c-myc oncogene: Structural consequences of translocation into the IgH locus in Burkitt lymphoma. Cell 1983;34:779-787.
22. Mercolino TJ, Herndier BG, Nolan TJ, and McGrath MS: Large cell "mixed-phenotype" lymphoma in AIDS. Ann NY Acad Sci 1992;651:409-421.
23. H gene expression among human follicular lymphomas. Blood 1991;78:1561-1568.
24. Sanger F, Nicklen S, and Coulson A: DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 1977;74: 5463-5467.
25. Pearson WR and Lipman DJ: Improved tools for biological sequence analysis. Proc Natl Acad Sci USA 1988;85:2444-2448.
26. Elgavish RA, Schroeder HW Jr: SAW: A graphical user interface for the analysis of immunoglobulin variable domain sequences. BioTechniques 1993;15:1066-1071.
27. Shlomchik MJ, Aucoin AH, Pisetsky DS, and Weigert MG: Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. Proc Natl Acad Sci USA 1987;84: 9150-9154.
28. Jukes TH and King JL: Evolutionary nucleotide replacements in DNA. Nature (London) 1979;281:605-606.
29. H locus. EMBO J 1988;7:727-738.
30. Shin EK, Matsuda F, Nagoaka H, Fukita Y, Imai T, Yokoyama K, Soeda E, and Honjo T: Physical map of the 3′ region of the human immunoglobulin heavy chain locus: Clustering of autoantibody-related variable segments in one haplotype. EMBO J 1991;10:3641-3645.
31. Soto-Gil RW, Olee T, Klink BK, Kenny TP, Robbins DL, Carson DA, and Chen PP: A systematic approach to defining the germline gene counterparts of a mutated autoantibody from a patient with rheumatoid arthritis. Arthr Rheum 1992;35:356-363.
32. H segments with different hypervariable loops. J Mol Biol 1992;227:776-798.
33. H locus. EMBO J 1988; 7:2003-2010.
34. Ichihara Y, Matsuoka H, and Kurosawa Y: Organization of human immunoglobulin heavy chain diversity gene loci. EMBO J 1988; 7:4141-4150.
35. Huang C and Stollar BD: A majority of Ig H chain cDNA of normal human adult blood lymphocytes resembles cDNA for fetal Ig and natural autoantibodies. J Immunol 1993;151:5290-5300.
36. Matsuda F, Shin EK, Nagaoka H, Matsumura R, Haino M, Fukita Y, Taka-ishi S, Imai T, Riley JH, Anand R, Soeda E, and Honjo T: Structure and physical map of 64 variable segments in the 3′ 0.8-megabase region of the human immunoglobulin heavy-chain locus. Nature Genet 1993;3:88-94.
37. Pascual V, Liu Y-J, Magalski A, deBouteiller O, Banchereau J, and Capra JD: Analysis of somatic mutation in five B cell subsets of human tonsil. J Exp Med 1994;180:329-339.
38. Ichiyoshi Y, Zhou M, and Casali P: A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germ-line" natural antibody template. J Immunol 1995;154:226-238.
39. H4-21 gene segment is required to encode anti-I and anti-I specificities. J Immunol 1992;149:2337-2344.
40. Yamada M, Wasserman BA, Shane RS, Caton AJ, and Rovera G: Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J Exp Med 1991;173:395-407.
41. Huang C, Stewart AK, Schwartz RS, and Stollar BD: Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes. J Clin Invest 1992;89:1331-1343.
42. Sanz I: Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions. J Immunol 1991;147: 1720-1729.
43. H gene in the expressed human B cell repertoire. J Exp Med 1993;177:409-418.
44. Dersimonian H, Schwartz RS, Barrett KJ, and Stollar BD: Relationship of human variable region heavy chain germline gene to genes encoding anti-DNA autoantibodies. J Immunol 1987; 139:2496-2501.
45. Pascual V, Randen I, Thompson K, Sioud M, Forre O, Natvig JB, and Capra JD: The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from EBV transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis: Further evidence that some autoantibodies are unmutated copies of germ line genes. J Clin Invest 1990;86:1320-1328.
46. Robbins DL, Kenny TP, Coloma MJ, Gavilondo-Cowley JV, Soto-Gil RW, Chen PP, and Lanick JW: Serologic and molecular characterization of a human monoclonal rheumatoid factor derived from rheumatoid synovial cells. Arthr Rheum 1990;33:1188-1195.
47. Silberstein LE, Litwin S, and Carmack CE: Relationship of variable region genes expressed by a human B cell lymphoma secreting pathologic anti-PR2 erythrocyte autoantibodies. J Exp Med 1989;169:1631-1643.
48. H4 genes in AIDS-associated B-cell lymphoma. Blood 1996;88:252-260.
49. Sanz I, Casali P, Thomas JW, Notkins AL, and Capra JD: Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families. J Immunol 1989;142:4054-4061.
50. Cairns EP, Kwong C, Misener V, Ip P, Bell DA, and Siminovitch KA: Analysis of variable region genes encoding a human anti-DNA antibody of normal origin. J Immunol 1989;143:685-691.
51. L regions of an anti-myelin/DNA antibody from a patient with peripheral neuropathy and chronic lymphocytic leukemia. J Immunol 1990;144:2821-2828.
52. H genes expressed by CD5 chronic lymphocytic leukemia producing pathologic IgM rheumatoid factor. J Immunol 1990;144:1526-1530.
53. Davidson A, Manheimer-Lory A, Aranow C, Peterson R, Hannigan N, and Diamond B: Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes. J Clin Invest 1990;85:1401-1409.
54. H4-21 gene segment is responsible for the major cross-reactive idiotype. J Immunol 1991; 146:4385-4391.
55. H gene elements encoding a human anti-DNA antibody. J Immunol 1987;139:1689-1693.
56. Van Es JH, Gmelig-Meyling FHJ, van de Akker WRM, Aanstoot H, Derksen RHWM, and Logtenberg T: Somatic mutations in the variable regions of a human IgG anti-double stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus. J Exp Med 1991;173:461-470.
57. Kabat EA, Wu TT, Perry HM, Gottesman KS, and Foeller C: Sequences of Proteins of Immunological Interest, 5th Ed. United States Department of Health and Human Services, U.S. Public Health Service, Bethesda, Maryland, 1991.