Multiple roles of inducible cyclooxygenase-2 and its selective inhibitors

Folia Pharmacologica Japonica

Volumn 109, Issue 6, 1997, Pages 247-258

  Katori, Makoto ^a   Majima, Masataka ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4' ACETYL 2' (2,4 DIFLUOROPHENOXY)METHANESULFONANILIDE; 5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; 6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; 6 OXOPROSTAGLANDIN F1 ALPHA; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CARRAGEENAN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; FLOSULIDE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN ENDOPEROXIDE; THROMBOXANE B2;

ABORTION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; BONE ATROPHY; CHILDBIRTH; COLON CARCINOMA; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG TARGETING; DYSMENORRHEA; ENDOMETRIUM; ENZYME INDUCTION; EXUDATE; GASTROINTESTINAL SYMPTOM; GRANULOMA; HUMAN; INFLAMMATION; KIDNEY DISEASE; MOUSE; NONHUMAN; OVULATION; PLEURISY; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; REVIEW; RHEUMATOID ARTHRITIS; STOMACH ULCER; SURVIVAL RATE; WOUND HEALING;

EID: 0031006675     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.109.247     Document Type: Review

References (43)

1. Harada Y, Tanaka K, Uchida Y, Ueno A, Oh-ishi S, Yamashita K, Ishibashi M, Miyazaki H and Katori M: Changes in the levels of prostaglandins and thromboxanes and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy - a profile analysis using gaschromatography-mass spectrometry. Prostaglandins 23, 881-896 (1982)
2. Uchida Y, Tanaka K, Harada Y, Ueno A and Katori M: Activation of plasma kallikrein-kinin system and its significant role in pleural fluid accumulation of rat carrageenin-induced pleurisy. Inflammation. 7, 121-131 (1983)
3. Katori M, Harada Y, Tanaka K, Miyazaki H, Ishibashi M and Yamashita Y: Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. Adv Prostaglandin Thromboxane Leukot Res 8, 1733-1737 (1980)
4. Harada Y, Hatanaka K, Saito M, Majima M, Ogino M, Kawamura M, Ohno T, Yang Q, Katori M and Yamamoto S: Detection of inducible prostaglandin H synthase-2 in cells in the exudate of rat carrageenin-induced pleurisy. Biomed Res 15, 127-130 (1994)
5. Katori M, Harada Y, Hatanaka K, Majima M, Kawamura M, Ohno T, Aizawa A and Yamamoto S: Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor. Adv Prostaglandin Thromboxane Leukot Res 23, 345-347 (1995)
6. 2 formation in rat carrageenin-induced pleurisy. Prostaglandins 51, 19-33 (1996)
7. Tanaka K, Kawasaki H, Kurata K, Aikawa Y, Tsukamoto Y and Inaba T: T-614, a novel antirheumatic drug, inhibits both the activity and function of cyclooxygenase-2 (COX-2) in cultured fibroblasts. Jpn J Pharmacol 67, 305-314 (1995)
8. Tanaka K: Role of COX-2 in air-pouch model. The Second World Congress of Inflammation. Brighton (Abstract) (1995)
9. Majima M, Hatanaka K, Kawamura M, Harada Y and Katori M: Expression of cyclooxygenase-2 (COX-2) in rat sponge implants and its role in neovascularization. Jpn J Pharmacol 72, Supp I , 92P (1997)
10. 2. Anat Rec 238, 68-76 (1994)
11. 1 in osteoblasts. J Clin Invest 93, 2490-2496 (1994)
12. Ben-Av P, Crofford LJ, Wilder RL and Hla T: Induction of vascular endothelial factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis. FEBS Lett 372, 83-87 (1995)
13. Mizuno H, Sakamoto C, Matsuda K, Wada K, Uchida T, Noguchi H, Akamatsu T and Kasuga M: Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 112, 387-397 (1997)
14. Shoda T, Hatanaka K, Saito M, Majima M, Ogino M, Kawamura M, Ohno T, Yang Q, Katori M and Yamamoto S: Induction of cyclooxygenease type-2 (COX-2) in rat endometrium at the peak of serum estradiol during the estrus cycle. Jpn J Pharmacol 69, 289-291 (1995)
15. Sirois J, Simmons DL and Richards JS: Hormonal regulation of membrane ribonucleic acid encoding a novel isoform of prostaglandin endoperoxide H synthase in rat preovulatory follicles. Induction in vivo and in vitro. J Biol Chem 267, 11586-11592 (1992)
16. Slater DM, Berger LC, Newton R, Moore GE and Bennett PR: Expression of cyclooxygenase types 1 and 2 in human fetal membrane at term. Am J Obstet Gynecol 172, 77-82 (1995)
17. Pilbeam CC, Kawaguchi H, Hakeda Y, Voznesensky O, Alander CB and Raisz LG: Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T-E1 cells. J Biol Chem 268, 25643 (1993)
18. Brum-Fernands AJ, Laport S, Heroux SL, Lora M, Patry C, Menard H-A, Dumais R and Leduc R: Expression of prostaglandin endoperoxide synthase-1 and prostaglandin endoperoxide synthase-2 in human osteoblasts. Biochem Biophys Res Commun 198, 955 (1994)
19. 2 in cultured neonatal mouse calvariae. Endocrinology 135, 1157-1164 (1994)
20. Onoe Y, Miyaura C, Kaminakayashiki T, Nagai Y, Noguchi K, Chen Q-R, Seo H, Ohta H, Nozawa S, Kudo I, et al: IL-13 and IL-14 inhibit bone reabsorption by suppressing cyclooxygenase-2 dependent PG synthesis in osteoblasts. J Immunol 156, 758-764 (1996)
21. Thun MJ, Namboodiri MM and Heath CW Jr: Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 325, 1593-1595 (1991)
22. Kargman SL, O'Neill GP, Vickers PJ, Evans JF, Mancini JA and Jothy S: Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res 25, 2556-2559 (1995)
23. Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C and Taketo M: Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci USA 92, 4482-4486 (1995)
24. Δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 87, 803-809 (1996)
25. Tsujii M and Dubois RN: Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83, 493-501 (1995)
26. Lu X, Xie W, Reed D, Bradshaw WS and Simmons DL: Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. Proc Natl Acad Sci USA 92, 7961-7965 (1995)
27. Dinchuk JE, Car BD, Focht RJ, Johnston JJ, Jaffe BD, Covington MB, Contel NR, Eng VM, Collins RJ, Czerniak PM, et al: Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 378, 406-409 (1995)
28. Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jannette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, et al: Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83, 473-482 (1995)
29. Langenbach R, Morham SG, Tiano HF, Loftin CD, Mahler JF, Lee CA, Goulding EH, Kluckman KD, et al: Prostaglandin synthase 1 gene disruption in mice reduced arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83, 483-492 (1995)
30. Suzuki Y, Harada Y, Ueno A, Katori M and Okabe H: Release of endogenous prostaglandins by mild hyperosmotic saline inhibits tetragastrin-stimulated gastric acid secretion in rats. Prostaglandins 32, 401-414 (1986)
31. 2 generation after administration of mild hyperosmotic saline solution into the gastric lumen. Eicosanoids 3, 23-27 (1990)
32. Futaki N, Takahashi S, Yokoyama M, Arai I, Higuchi S and Otomo S: NS-398, a new antiinflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase(COX-2) activity in vitro. Prostaglandins 47 55-59 (1995)
33. Hori Y, Katori M, Harada Y, Uchida Y and Tanaka K: Potentiation of bradykinin-induced nociceptive response by arachidonate metabolites in dogs. Eur J Pharmacol 312, 47-52 (1986)
34. Stadler P, Armstrong D, Margalith D, Saraga E, Stolte M, Lualdi P, Mautone G and Blum AL: Diclofenac delays healing of gastroduodenal mucosal lesions. Double-blind, placebo-controlled endoscopic study in healthy volunteers. Dig Dis Sci 36, 594-600 (1991)
35. Pulkkinen MO: Alterrations in intrauterine pressure, memstrual fluid prostaglandin F level, and pain in dysmenorrheic women treated with nimesulide. J Clin. Pharmacol. 27, 65-69 (1987)