Synthesis of several 3-substituted 2-trifluoromethylindoles via Mannich reaction of 2-trifluoromethylindoles

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 5, 1997, Pages 932-935

  Miyashita, Kazuyuki ^a   Kondoh, Katsunori ^a   Tsuchiya, Katsutoshi ^a   Miyabe, Hideto ^a   Imanishi, Takeshi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

2 trifluoromethylindole; Mannich reaction; Nucleophilic substitution; Synthesis

Indexed keywords

ALDEHYDE DERIVATIVE; AMINE; CARBOXYLIC ACID; INDOLE DERIVATIVE; INDOLEACETIC ACID DERIVATIVE; MANNICH BASE; NITRILE; OXYPERTINE; TRYPTAMINE DERIVATIVE; TRYPTOPHAN DERIVATIVE;

AMINATION; ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; HYDROLYSIS; REDUCTION;

EID: 0031006228     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.932     Document Type: Article

References (9)

1. A part of this work has appeared in a preliminary communication: Miyashita K., Tsuchiya K., Kondoh K., Miyabe H., Imanishi T., Heterocycles, 42, 513-516 (1996).
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