cAMP-dependent protein kinase modulates expiratory neurons in vivo

Journal of Neurophysiology

Volumn 77, Issue 3, 1997, Pages 1119-1131

  Lalley, Peter M ^a   Pierrefiche, Olivier ^a   Bischoff, Anne M ^a   Richter II, Diethelm W ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

AFTERHYPERPOLARIZATION; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; CAT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; HYPERPOLARIZATION; MALE; NERVE CELL; NERVE POTENTIAL; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; SECOND MESSENGER;

EID: 0031004310     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.77.3.1119     Document Type: Article

References (80)

1. AGOPYAN, N., TOKUTOMI, N., AND AKAIKE, N. Protein kinase A-mediated phosphorylation reduces only the fast desensitizing glycine current in acutely dissociated ventromedial hypothalamic neurons. Neuroscience 56: 605-615, 1993.
2. AKASU, T. AND SHOJI, S. cAMP-dependent inward rectifier current in neurons of the rat suprachiasmatic nucleus. Pfluegers Arch. 429: 117-125, 1994.
3. AKINS, P. T. AND MCCLESKY, E. W. Characterization of potassium currents in adult rat sensory neurons and modulation by opioids and cyclic AMP. Neuroscience 56: 759-769, 1993.
4. ALBERTS, B., BRAY, D., LEWIS, J., RAFF, M, ROBERTS, K., AND WATSON, J. D. (Editors). Vesicular traffic in the secretory and endocytic pathways. In: Molecular Biology of the Cell (3rd ed.). New York: Garland, 1994, chapt. 13, p. 628-629.
5. B receptors to the same channels in hippocampus. Science Wash. DC 234: 1261-1265, 1986.
6. ANWYL, R. Neurophysiological actions of 5-hydroxytryptamine in the vertebrate nervous system. Prog. Neurobiol. 35: 451-468, 1990.
7. ARITA, A., ONIMURA, H., AND HOMMA, I. Effects of cAMP on respiratory rhythm generation in brainstem-spinal cord preparation from newborn rat. Brain Res. 605: 193-199, 1993.
8. BAINTON, C. B. AND KIRKWOOD, P. A. The effects of carbon dioxide on the tonic and the rhythmic discharges of expiratory bulbospinal neurones. J Physiol. Lond. 296: 291-314, 1979.
9. BALLANTYNE, D. AND RICHTER, D. W. The non-uniform character of expiratory synaptic activity in expiratory bulbospinal neurones of the cat. J Physiol. Lond. 370: 433-456, 1986.
10. BARRACO, R. A., SCHOENER, E. P., POLASEK, P. M., SIMPSON, L. L., JANUSZ, C. J., AND PARIZON, M. Respiratory effects of cyclic AMP following injection into the nucleus tractus solitarius of rats. Neuropharmacology 27: 1285-1294, 1988.
11. BERGER, A. L., AVERILL, D. B., AND CAMERON, W. E. Morphology of inspiratory neurons located in the ventrolateral nucleus of the tractus solitarius of the cat. J Comp. Neurol. 224: 60-70, 1984.
12. BIANCHI, A. L., DENAVIT-SAUBIÉ, M., AND CHAMPAGNAT, J. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol. Rev. 75: 1-45, 1995.
13. BLACKSTONE, C., MURPHY, T. H., MOSS, S. J., BARABAN, J. M., AND HUGANIR, L. Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA-preferring glutamate receptors. J Neurosci. 14: 7585-7593, 1994.
14. BOBKER, D. H. AND WILLIAMS, J. T. Ion conductances affected by 5-HT receptor subtypes in mammalian neurons. Trends Neurosci. 13: 169-173, 1990.
15. B receptor pharmacology. Annu. Rev. Pharmacol. Toxicol. 33: 109-147, 1993.
16. BROWNING, M. D., BUREAU, M., DUDEK, E. M., AND OLSEN, R. W. Protein kinase C and cAMP-dependent protein kinase phosphorylate the b-sub-unit of the purified gamma-aminobutyric acid A receptor. Proc. Natl. Acad. Sci. USA 87: 1315-1318, 1990.
17. CAPOGNA, M., GAHWILER, B. H., AND THOMPSON, S. M. Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro. J Neurosci. 15: 1249-1260, 1995.
18. CERNE, R., RUSIN, K. I., AND RANDIC, M. Enhancement of the N-methyl-D-aspartate response in spinal dorsal horn neurons by cAMP-dependent protein kinase. Neurosci. Lettt. 161: 124-128, 1993.
19. CHAMPAGNAT, J. AND RICHTER, D. W. Second messenger mediated modulation of the excitability of respiratory neurons. Neuroreport 4: 861-863, 1993.
20. + conductances in expiratory pattern generation in anaesthetized cats. J. Physiol. Lond. 479: 127-138, 1994.
21. CHENG, H.-C., KEMP, B. E., PEARSON, R. B., SMITH, A. J., MISCONI, L., VAN PATTEN, S. M., AND WALSH, D. A. A potent synthetic peptide inhibitor of the c AMP-dependent protein kinase. J Biol. Chem. 261: 989-992, 1986.
22. COLLINGRIDGE, G. L. AND LESTER, R.A.J. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Rev. 40: 143-210, 1989.
23. COLWELL, C. S. AND LEVINE, M. S. Excitatory synaptic transmission in neostrital neurons: regulation by cyclic AMP-dependent mechanisms. J Neurosci. 15: 1704-1713, 1995.
24. DANURA, T., KUROKAWA, T., YAMASHITTA, A., AND ISHTBASHI, S. Effective inhibition by pentobarbital of forskolin-stimulated adenylate cyclase activity in rat brain. Chem. Pharm. Bull. Tokyo 37: 3142-3144, 1989.
25. DIETZEL, I. D., BRUNS, D., POLDER, H. R., AND LUX, H. D. Voltage clamp recording. In: Practical Electrophysiological Methods, edited by H. Kettemmann and R. Grantyn. New York: Wiley-Liss, 1992.
26. EWALD, D. A. AND LEVITAN, I. B. Ion channels regulated by calcium. In: Neuromodulation, edited by L. K. Kaczmarek and I. B. Levitan. New York: Oxford Univ. Press, 1987, p. 138-158.
27. FALLERT, M., BOHMER, G., DINSE, H.R.O., SOMMER, T. J., AND BITTNER, A. Microelectrophoretic application of putative neurotransmitters onto various types of bulbar respiratory neurons. Arch. Ital. Biol. 117: 1-12, 1979.
28. FINKEL, A. S. AND REDMAN, S. J Theory and operation of a single microelectrode voltage clamp. J Neurosci. Methods 11: 101-127, 1984.
29. FIORILLO, C. D. AND WILLIAMS, J. T. Opioid desensitization: interactions with G-protein-coupled receptors in the locus coeruleus. J Neurosci. 16: 1479-1485, 1996.
30. GEREAU, R. W. AND CONN, P. J A cyclic AMP-dependent form of associative synaptic plasticity induced by coactivation of beta-adrenergic receptors and metabotropic glutamate receptors in rat hippocampus. J Neurosci. 14: 3310-3318, 1994.
31. + currents, increasing spike duration and excitability in Aplysia sensory neurons. Proc. Natl. Acad. Sci. USA 89: 11481-11485, 1992.
32. sα-dependent cyclic AMP production in S49 mouse lymphoma cells. J. Neurochem. 64: 2559-2566, 1995.
33. GREENE, C. C., SCHWINDT, P. C., AND CRILL, W. E. Properties and ionic mechanisms of a metabotropic glutamate receptor-mediated slow afterdepolarization in neocortical neurons. J Neurophysiol. 72: 693-704, 1994.
34. GREENGARD, P., JEN, J., NAIRN, A. C., AND STEVENS, C. F. Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons. Science Wash. DC 253: 1135-1138, 1991.
35. GREGA, D. S. AND MACDONALD, R. L. Activation of adenylate cyclase and cyclic AMP prolong calcium-dependent action potentials of mouse sensory neurons by reducing a voltage-dependent potassium conductance. J Neurosci. 7: 700-707, 1987.
36. 2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog. Neurobiol. 40: 277-318, 1993.
37. HAJI, A., PIERREFICHE, O., LALLEY, P. M., AND RICHTER, D. W. Protein kinase C pathways control respiratory pattern generation in the cat. J Physiol. Lond. 494: 297-306, 1996.
38. HAJI, A. AND TAKEDA, R. Microiontophoresis of baclofen on membrane potential and input resistance in bulbar respiratory neurons in the cat. Brain Res. 622: 294-298, 1993.
39. HOYER, D., CLARKE, D. E., FOZARD, J. R., HARTIG, P. R., MARTIN, G. R., MYLECHARANE, E. J., SAXENA, P. R., AND HUMPHREY, P. P. A. International union of pharmacology classification of receptors for 5-hydroxy-tryptamine (serotonin). Pharmacol. Rev. 46: 157-203, 1994.
40. JOHNSON, S. M., SMITH, J. C., AND FELDMAN, J. L. Modulation of respiratory rhythm in vitro: role of gi/o-protein mediated mechanisms. J Appl. Physiol. 80: 2120-2123, 1996.
41. KACZMAREK, L. K. AND LEVITAN, I. B. (Editors). Neuromodulation, the Biochemical Control of Neuronal Excitability. New York: Oxford Univ. Press, 1987, p. 286.
42. KNIGHTON, D. R., ZHENG, J., TEN EYCK, L. F., XUONG, N.-H., TAYLOR, S. S., AND SOWADSKI, J. M. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science Wash. DC 253: 414-420, 1991.
43. KREUTER, F., RICHTER, D. W., CAMERER, H., AND SENEKOWITSCH, R. Morphological and electrical description of medullary respiratory neurons of the cat. Pfluegers Arch. 372: 7-16, 1977.
44. LALLEY, P. M., BISCHOFF, A. M., AND RICHTER, D. W. 5-HT-1A receptor-mediated modulation of medullary respiratory neurones in the cat. J. Physiol. Lond. 476: 117-130, 1994.
45. 2 receptor-controlled modulation of medullary respiratory neurones in the cat. J. Physiol. Lond. 487: 653-661, 1995.
46. LAURENZA, A., SUTKOWSKI, E. M., AND SEAMON, K. B. Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action? Trends Pharmacol. Sci. 10: 442-447, 1989.
47. Liu, Y. AND LASATER, E. M. Calcium currents in turtle retinal ganglion neurons. II. Dopamine modulation via a cyclic AMP-dependent mechanism. J Neurophysiol. 71: 743-752, 1994.
48. LONG, E. E. AND DUFFIN, J. The medullary respiratory neurons: a review. Can. J Physiol. Pharmacol. 62: 161-182, 1984.
49. o-type GTP-binding protein. J Neurosci. 14: 3842-3851, 1994.
50. NICHOLLS, J. G., MARTIN, A. R., AND WALLACE, B. G. (Editors). Indirect mechanisms of synaptic transmission. In: From Neuron to Brain (3rd ed.). Sunderland, MA: Sinauer, 1992, chapt. 8, p. 237-266.
51. NICOLL, R. A. The coupling of neurotransmitter receptors to ion channels in the brain. Science Wash. DC 241: 545-552, 1988.
52. NICOLL, R. A., MALENKA, R. C., AND KAUER, J. A. Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol. Rev. 70: 513-565, 1990.
53. PIERREFICHE, O., BISCHOFF, A. M., LALLEY, P. M., AND RICHTER, D. W. cAMP-dependent protein kinase A increases the excitability of expiratory neurons of cat. Soc. Neurosci. Abstr. 21: 2069, 1995.
54. PIERREFICHE, O., SCHMID, K., FOUTZ, A. S., AND DENAVIT-SAUBIÉ, M. Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medulla. Neuropharmacology 30: 429-440, 1991.
55. RAYMOND, L. A., BLACKSTONE, C. D., AND HUGANIR, R. L. Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity. Trends Neurosci. 16: 147-153, 1993.
56. RICHTER, D. W. Neural regulation of respiration: rhythmogenesis and afferent control. In: Comprehensive Human Physiology: From Cellular Mechanisms to Integration, edited by R. Gregor and U. Windhorst. Heidelberg, Germany: Springer-Verlag, 1996, vol. 2, chapt. 105, p. 2079-2095.
57. RICHTER, D. W., BALLANYI, K., AND SCHWARZACHER, S. Mechanisms of respiratory rhythm generation. Curr. Opin. Neurobiol. 2: 788-793, 1992.
58. RICHTER, D. W., BISCHOFF, A., ANDERS, K., BELLINGHAM, M., AND WINDHORST, K. Response of the medullary respiratory network of the cat to hypoxia. J Physiol. Lond. 443: 231-256, 1991.
59. RICHTER, D. W., CHAMPAGNAT, J., JACQUIN, T., AND BENACKA, R. Calcium currents and calcium-dependent potassium currents in mammalian medullary respiratory neurones. J Physiol. Lond. 470: 23-33, 1993.
60. RICHTER, D. W., PIERREFICHE, O., LALLEY, P. M., AND POLDER, H. R. Voltage clamp analysis of neurons within deep layers of the brain. J Neurosci. Methods 67: 121-131, 1996.
61. RUDY, B. Diversity and ubiquity of K channels. Neuroscience 25: 729-749, 1988.
62. SCIANCALEPORE, M. AND CHERUBINI, E. Protein kinase A-dependent increase in frequency of miniature GABAergic currents in rat CA3 hippocampal neurons. Neurosci. Lett. 187: 91-994, 1995.
63. SCHMIDT, C., BELLINGHAM, M. C., AND RICHTER, D. W. Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized cat. J Physiol. Lond. 483: 769-781, 1995.
64. SCHMITT, H. AND MEVES, H. Bovine serum albumin increases the low-voltage-activated calcium current of NG108-15 neuroblastoma × glioma neurons. Brain Res. 656: 375-380, 1994.
65. SCHWARACHER, S. W., SMITH, J. C., AND RICHTER, D. W. Pre-Boetzinger complex in the cat. J Neurophysiol. 73: 1452-1461, 1995.
66. SCHOEPP, D. D. AND CONN, P. J Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol. Sci. 14: 13-20, 1993.
67. SCHWARTZ, R. D., HEUSCHNEIDER, G., EDGAR, P. P., AND COHN, J. A. cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain. Mol. Pharmacol. 39: 370-375, 1991.
68. SHEPHERD, G. M. Second messengers. In: Neurobiology (3rd ed.). New York: Oxford Univ. Press, 1994 p. 760.
69. SNEDECOR, G. W. Sampling from a normally distributed population. In: Statistical Methods Applied to Experiments in Agriculture and Biology (5th ed.), edited by G. W. Snedecor and W. G. Cochran. Ames, IA: Iowa Univ. Press, 1962, p. 534.
70. STRICKHOLM, A. A supercharger for single electrode voltage and current clamping. J Neurosci. Methods 61: 47-52, 1995a.
71. STRICKHOLM, A. A single electrode voltage, current- and patch-clamp amplifier with complete stable series resistance compensation. J Neurosci. Methods 61: 53-66, 1995b.
72. SUDLOW, L. C. AND GILLETTE, R. Cyclic AMP-gated sodium current in neurons of the pedal ganglion of Pleurobranchaea californica is activated by serotonin. J Neurophysiol. 73: 2230-2236, 1995.
73. SWOPE, S. L., MOSS, S. J., BLACKSTONE, C. D., AND HUGANIR, R. L. Phosphorylation of ligand-gated ion channels; a possible mode of synaptic plasticity. FASEB J. 6: 2514-2522, 1992.
74. TAIWO, Y. O., HELLER, P. H., AND LEVINE, J. D. Mediation of serotonin hyperalgesia by the cAMP second messenger system. Neuroscience 48: 479-483, 1992.
75. TORRES, G. E., CHAPUT, Y., AND ANDRADE, R. Cyclic AMP and protein kinase A mediate 5-hydroxytryptamine type 4 receptor regulation of calcium-activated potassium current in adult hippocampal neurons. Mol. Pharmacol. 47: 191-197, 1995.
76. VAN HAASTERT, P.J.M., VAN DRIEL, R. V., JASTORFF, B., BARANIAK, J., STEC, J., AND DE WIT, J.W.J. Competitive cAMP antagonists for cAMP-receptor proteins. Biol. Chem. 259: 10020-10024, 1984.
77. WANG, L.-Y., SALTER, M. W., AND MACDONALD, J. F. Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science Wash. DC 253: 1132-1135, 1991.
78. WATLING, K. J., KEBABIAN, J. W., AND NEUMEYER, J. L. The RBI Handbook of Receptor Classification and Signal Transduction. Natick, MA: Research Biochemicals International, 1995.
79. + currents and the cAMP-dependent modulation in cultured Drosophila mushroom body neurons identified by 1acZ expression (Abstract). J. Neurosci. 15: 1025, 1995.
80. ZIFA, E. AND FILLION, G. 5-Hydroxytryptamine receptors. Pharmacol. Rev. 44: 401-458, 1992.