Replacement of the Bizelesin ureadiyl linkage by a guanidinium moiety retards translocation from monoalkylation to cross-linking sites on DNA

Journal of the American Chemical Society

Volumn 119, Issue 15, 1997, Pages 3434-3442

  Lee, Seung Joo ^a   Seaman, Frederick C ^a   Sun, Daekyu ^b   Xiong, Heping ^c   Kelly, Robert C ^c   Hurley, Laurence H ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b CTRC Institute for Drug Development   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIZELESIN;

ARTICLE; DNA BINDING; DNA STRUCTURE; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; THERMODYNAMICS;

EID: 0031000369     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja963873v     Document Type: Article

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