Cross-linkage by "intact" Bizelesin and bisalkylation by the "separated halves" of the Bizelesin dimer: Contrasting drug manipulation of DNA conformation (5′-TAATTA-3′) directs alkylation toward different adenine targets

Journal of the American Chemical Society

Volumn 118, Issue 23, 1996, Pages 5383-5395

  Seaman, Frederick C ^a   Chu, Jianxiong ^a   Hurley, Laurence ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSS LINKING REAGENT;

ARTICLE; DNA ALKYLATION; DNA CROSS LINKING; DNA STRUCTURE; DRUG DESIGN; GEL ELECTROPHORESIS; NUCLEAR MAGNETIC RESONANCE;

EID: 0029937181     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja960017a     Document Type: Article

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