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Volumn 32, Issue 6, 1997, Pages 515-522
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Selective endothelin A receptor antagonists. 2. Discovery and structure-activity relationships of 5-ketopentanoic acid derivatives
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Author keywords
Endothelin receptor antagonist; Ketopentanoic acid; Structure activity relationship; Vasodilator activity
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Indexed keywords
4 TERT BUTYL N [6 (2 HYDROXYETHOXY) 5 (3 METHOXYPHENOXY) 4 PYRIMIDINYL]BENZENESULFONAMIDE;
CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL);
ENDOTHELIN A RECEPTOR;
ENDOTHELIN A RECEPTOR ANTAGONIST;
ENDOTHELIN B RECEPTOR;
VALERIC ACID DERIVATIVE;
ANIMAL CELL;
ANIMAL TISSUE;
AORTA;
ARTICLE;
ATHEROSCLEROSIS;
BINDING AFFINITY;
CEREBELLUM;
CONTROLLED STUDY;
DRUG DEVELOPMENT;
DRUG SYNTHESIS;
ENANTIOMER;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYPERTENSION;
IN VITRO STUDY;
ISCHEMIA;
NONHUMAN;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
RAT;
RECEPTOR AFFINITY;
STRUCTURE ACTIVITY RELATION;
VASODILATATION;
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EID: 0030998237
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(97)84014-7 Document Type: Article |
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Times cited : (14)
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References (13)
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