DRB4 promoter polymorphism in DR7 individuals: Correlation with DRB4 pre-mRNA and mRNA levels

Immunogenetics

Volumn 45, Issue 6, 1997, Pages 371-378

  Leën, Mathijs P J M ^a   Gorski, Jack ^a  

^a BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; MESSENGER RNA; RIBONUCLEASE;

ALLELE; ARTICLE; DNA POLYMORPHISM; GENE EXPRESSION; HLA SYSTEM; HUMAN; MONONUCLEAR CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION;

ALLELES; BASE SEQUENCE; GENE EXPRESSION REGULATION; HLA-DR ANTIGENS; HLA-DR7 ANTIGEN; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RNA PRECURSORS; RNA, MESSENGER;

HUMAN HERPESVIRUS 4; TRIXIS;

EID: 0030997182     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050218     Document Type: Article

References (22)

1. Bell, J. I., Denney, D. Jr., MacMurray, A., Foster, L., Watling, D., and McDevitt, H. O. Molecular mapping of class II polymorphisms in the human major histocompatibility complex. J Immunol 139: 562-573, 1987
2. Berdoz, J., Gorski, J., Termijtelen, A.-M., Dayer, J.-M., Irlé, C., Schendel, D., and Mach, B. Constitutive and induced expression of the individual HLA-DR β and α chain loci in different cell types. J Immunol 139: 1336-1341, 1987
3. Curtsinger, J. M., Hilden, J. M., S. Cairns, J., and Bach, F. H. Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR β-chain cDNA clones. Proc Natl Acad Sci USA 84: 209-213, 1987
4. Emery, P., Mach, B., and Reith, W. The different level of expression of HLA-DRB1 and -DRB3 genes is controlled by conserved isotypic differences in promoter sequences. Hum Immunol 38: 137-147, 1993
5. Glisin, V., Crkvenjakov, R., and Byus, C. Ribonucleic acid isolated by CsC1 centrifugation. Biochem J 13: 2633-2637, 1974
6. Gorski, J., Rollini, P., Mach, B. Structural comparison of the genes of two HLA-DR supertypic groups: The loci encoding DRw52 and DRw53 are not truly allelic. Immunogenetics 25: 397-402, 1987a
7. Gorski, J., Tilanus, M., Giphart, M., Mach, B. Oligonucleotide genotyping shows that alleles at the HLA-DRβIII locus of the DRw52 supertypic group segregate independently of the known DR or Dw specificities. Immunogenetics 25: 79-83, 1987b
8. Gregerson, P. K., Moriuchi, T., Karr, R. W., Obata, F., Moriuchi, J., Maccari, J., Goldberg, D., Winchester, R. J., and Silver, J. Polymorphism of HLA-DRβ chains in DR4, -7, and -9 haplotypes: Implications for the mechanisms of allelic variation. Proc Natl Acad Sci USA 83: 9149-9153, 1986
9. Jabrane-Ferrat, N., Fontes, J. D., Boss, J. M., and Peterlin, B. M. Complex architecture of the major histocompatibility complex class II promoters: reiterated motifs and conserved protein-protein interactions. Mol Cell Biol 16:4683-4690, 1996
10. Leën, M. P. J. M. and Gorski, J. Differential expression of isomorphic DRβ genes is not a sole function of transcription. Hum Immunol 50: 111-120, 1996
11. Louis, P., Eliaou, J.-F., Kerlan-Candon, S., Pinet, V., Vincent, R., and Clot, J. Polymorphism in the regulatory region of HLA-DRB genes correlating with haplotype evolution. Immunogenetics 38: 21-26, 1993
12. Matsui, Y., Alosco, S. M., Awdeh, Z., Duquesnoy, R. J., Page, P. L., Hartzman, R., Raum, D., Alper, C. A., and Yunis, E. J. Linkage disequilibrium of HLA-A1, B8, DR5, SC01 and SB4 with the HLA-A26, Bw38, Dw10, DR4, SC21 extended haplotypes. Immunogenetics 20: 623-631, 1984
13. Miller, S. A., Dykes, D. D., Polesky, H. F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215, 1988
14. Perfetto, C., Zacheis, M., McDaid, D., Meador III, J. W., Schwartz, B. D. Polymorphism in the promoter region of HLA-DRB genes. Hum Immunol 36: 27-33, 1993
15. Pujol-Borrell, R., Todd, I., Doshi, M., Bottazzo, G. F., Sutton, R., Grey, D., Adolf, R. G., and Feldmann, M. HLA class II induction in human islet cells by interferon-γ plus tumor necrosis factor or lymphotoxin. Nature 326: 304-306, 1987
16. Stunz, L. L., Karr, R. W., and Anderson, R. A. HLA-DRB1 and -DRB4 genes are differentially regulated at the transcriptional level. J Immunol 143: 3081-3086, 1989
17. Sutton, V. R. and Knowles, R. W. An aberrant DRB4 null gene transcript is found that could encode a novel HLA-DR β chain. Immunogenetics 31: 112-117, 1990
18. Sutton, V. R., Kienzle, B. K., and Knowles, R. W. An altered splice site is found in the DRB4 gene that is not expressed in HLA-DR7, Dw11 individuals. Immunogenetics 29: 317-322, 1989
19. Tilanus, M. G. J., Morolli, B., van Eggermond, M. C. J. A., Schreuder, G. M. Th., de Vries, R. R. P., and Giphart, M. J. Dissection of HLA class II haplotypes in HLA-DR4 homozygous individuals. Immunogenetics 23: 333-340, 1986
20. Vincent, R., Louis, P., Gongora, C., Papa, I., Clot, J., Eliaou, J.-F. Quantitative analysis of the expression of the HLA-DRB genes at the transcriptional level by competitive polymerase chain reaction. J Immunol 156: 603-610, 1996
21. Voliva, C. F., Aronheim, A., Walker, M. D., and Peterlin, B. M. B-cell factor 1 is required for optimal expression of the DRA promoter in B cells. Mol Cell Biol 12: 2383-2390, 1992
22. Young, J. A. T., Wilkinson, D., Bodiner, W. F. and Trowsdale, J. Sequence and evolution of the HLA-DR7- and -DRw53-associated β-chain genes. Proc Natl Acad Sci USA 84: 4929-4933, 1987