메뉴 건너뛰기




Volumn 138, Issue 6, 1997, Pages 2552-2558

Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN C;

EID: 0030996380     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.6.5215     Document Type: Article
Times cited : (44)

References (45)
  • 1
    • 0023192181 scopus 로고
    • Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor 1, and epidermal growth factor in an intact cell
    • Kadowaki T, Koyasu S, Nishida E, Tobe K, Izumi T, Takaku F, Sakai H, Yahara I, Kasuga M 1987 Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor 1, and epidermal growth factor in an intact cell. J Biol Chem 262:7342-7350
    • (1987) J Biol Chem , vol.262 , pp. 7342-7350
    • Kadowaki, T.1    Koyasu, S.2    Nishida, E.3    Tobe, K.4    Izumi, T.5    Takaku, F.6    Sakai, H.7    Yahara, I.8    Kasuga, M.9
  • 3
    • 0026541299 scopus 로고
    • Substrates and signaling complexes: The tortured path to insulin action
    • Roth RA, Zhang B, Chin JE, Kovacina K 1992 Substrates and signaling complexes: the tortured path to insulin action. J Biol Chem 48:12-18
    • (1992) J Biol Chem , vol.48 , pp. 12-18
    • Roth, R.A.1    Zhang, B.2    Chin, J.E.3    Kovacina, K.4
  • 6
    • 0027772552 scopus 로고
    • The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the MAP kinase pathway and induces cell proliferation
    • Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M 1993 The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the MAP kinase pathway and induces cell proliferation. Cell 75:887-897
    • (1993) Cell , vol.75 , pp. 887-897
    • Sontag, E.1    Fedorov, S.2    Kamibayashi, C.3    Robbins, D.4    Cobb, M.5    Mumby, M.6
  • 7
    • 0025924682 scopus 로고
    • Coordinate regulation of pp90rsk and a distinct-protein serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro
    • Chung J, Chen RH, Blenis J 1991 Coordinate regulation of pp90rsk and a distinct-protein serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro. Mol Cell Biol 11:1868-1874
    • (1991) Mol Cell Biol , vol.11 , pp. 1868-1874
    • Chung, J.1    Chen, R.H.2    Blenis, J.3
  • 8
    • 0023818515 scopus 로고
    • 2+-inhibitable protein kinase that phosphorylates microtubule-associated protein 2 in vitro by growth factors, phorbol esters, and serum in quiescent cultured human fibroblasts
    • 2+-inhibitable protein kinase that phosphorylates microtubule-associated protein 2 in vitro by growth factors, phorbol esters, and serum in quiescent cultured human fibroblasts. J Biol Chem 263:5396-5401
    • (1988) J Biol Chem , vol.263 , pp. 5396-5401
    • Hoshi, M.1    Nishida, E.2    Sakai, H.3
  • 9
    • 0028357579 scopus 로고
    • Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation
    • Mastick DD, Kato H, Roberts Jr CT, LeRoith D, Saltiel AR 1994 Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation. Endocrinology 135:214-222
    • (1994) Endocrinology , vol.135 , pp. 214-222
    • Mastick, D.D.1    Kato, H.2    Roberts Jr., C.T.3    LeRoith, D.4    Saltiel, A.R.5
  • 10
    • 0026641090 scopus 로고
    • Activation of mitogen-activated protein kinase kinase by v-Raf in NIH-3T3 cells and in vitro
    • Dent P, Haser W, Haystead TA, Vincent LA, Roberts Sturgill TW 1992 Activation of mitogen-activated protein kinase kinase by v-Raf in NIH-3T3 cells and in vitro. Science 257:1404-1407
    • (1992) Science , vol.257 , pp. 1404-1407
    • Dent, P.1    Haser, W.2    Haystead, T.A.3    Vincent, L.A.4    Roberts Sturgill, T.W.5
  • 11
    • 0026701092 scopus 로고
    • Mitogen-activated protein kinase activation resulting from selective oncogene expresssion in NIH-3T3 cells and Rat 1a cells
    • Gallego C, Gupta SK, Heasley L, Qian NX, Johnson GL 1992 Mitogen-activated protein kinase activation resulting from selective oncogene expresssion in NIH-3T3 cells and Rat 1a cells. Proc Natl Acad Sci USA 89:7355-7359
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7355-7359
    • Gallego, C.1    Gupta, S.K.2    Heasley, L.3    Qian, N.X.4    Johnson, G.L.5
  • 13
    • 0027583888 scopus 로고
    • MAP kinase and the activation of quiescent cells
    • Ruderman JV 1993 MAP kinase and the activation of quiescent cells. Curr Opin Cell Biol 5:207-213
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 207-213
    • Ruderman, J.V.1
  • 14
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S, Paterson H, Kemp P, Marshall CJ 1994 Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-852
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 15
    • 0028270718 scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphobol-13-acetate requires Raf and is necessary for transformation
    • Troppmair J, Bruder JT, Munoz H, Lloyd PA, Kyriakis J, Banerjee P, Avruch J, Rapp UR 1994 Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphobol-13-acetate requires Raf and is necessary for transformation. J Biol Chem 269:7030-7035
    • (1994) J Biol Chem , vol.269 , pp. 7030-7035
    • Troppmair, J.1    Bruder, J.T.2    Munoz, H.3    Lloyd, P.A.4    Kyriakis, J.5    Banerjee, P.6    Avruch, J.7    Rapp, U.R.8
  • 17
    • 0025064397 scopus 로고
    • Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase
    • Endemann G, Yonezawa K, Roth RA 1990 Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase. J Biol Chem 265:396-400
    • (1990) J Biol Chem , vol.265 , pp. 396-400
    • Endemann, G.1    Yonezawa, K.2    Roth, R.A.3
  • 19
    • 0026566156 scopus 로고
    • Insulin-like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor
    • Yamamoto K, Palpetina EG, Mowham CP 1992 Insulin-like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor. Endocrinology 130:1490-1498
    • (1992) Endocrinology , vol.130 , pp. 1490-1498
    • Yamamoto, K.1    Palpetina, E.G.2    Mowham, C.P.3
  • 20
    • 0027512244 scopus 로고
    • The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro
    • Giorgetti S, Ballotti R, Kowalski-Chaubel A, Tartare S, Van Obberghen E 1993 The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro. J Biol Chem 268:7358-7364
    • (1993) J Biol Chem , vol.268 , pp. 7358-7364
    • Giorgetti, S.1    Ballotti, R.2    Kowalski-Chaubel, A.3    Tartare, S.4    Van Obberghen, E.5
  • 21
    • 0029096649 scopus 로고
    • Insulin-like growth factor induces phosphorylation of immunoreactive insulin receptor substrate and its association with phosphatidylinositol 3-kinase in human thymocytes
    • Kooijman R, Lauf JJ, Kappers AC, Rijkers GT 1995 Insulin-like growth factor induces phosphorylation of immunoreactive insulin receptor substrate and its association with phosphatidylinositol 3-kinase in human thymocytes. J Exp Med 182:593-597
    • (1995) J Exp Med , vol.182 , pp. 593-597
    • Kooijman, R.1    Lauf, J.J.2    Kappers, A.C.3    Rijkers, G.T.4
  • 22
    • 0029118603 scopus 로고
    • Wortmannin as an unique probe for an intracellular signaling protein, phosphatidylinositide 3-kinase
    • Ui M, Okada T, Hazeki K, Hazeki O 1995 Wortmannin as an unique probe for an intracellular signaling protein, phosphatidylinositide 3-kinase. Trends Biochem Sci 20:303-307
    • (1995) Trends Biochem Sci , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 23
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3-kinase
    • Kapeller R, Cantley LC 1994 Phosphatidylinositol 3-kinase. Bioessays 16:565-576
    • (1994) Bioessays , vol.16 , pp. 565-576
    • Kapeller, R.1    Cantley, L.C.2
  • 24
    • 15844368106 scopus 로고    scopus 로고
    • Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor-I receptor
    • Li S, Resnicoff M, Baserga R 1996 Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor-I receptor. J Biol Chem 271:12254-12260
    • (1996) J Biol Chem , vol.271 , pp. 12254-12260
    • Li, S.1    Resnicoff, M.2    Baserga, R.3
  • 25
    • 0030064571 scopus 로고    scopus 로고
    • Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor
    • Blakesley VA, Kalebic T, Helman LJ, Stannard B, Faria TN, Roberts Jr CT, LeRoith D 1996 Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor. Endocrinology 137:410-417
    • (1996) Endocrinology , vol.137 , pp. 410-417
    • Blakesley, V.A.1    Kalebic, T.2    Helman, L.J.3    Stannard, B.4    Faria, T.N.5    Roberts Jr., C.T.6    LeRoith, D.7
  • 26
    • 0028863148 scopus 로고
    • The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis
    • Hernández-Sánchez C, Blakesley VA, Kalebic T, Helman L, LeRoith D 1995 The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis. J Biol Chem 270:29176-29181
    • (1995) J Biol Chem , vol.270 , pp. 29176-29181
    • Hernández-Sánchez, C.1    Blakesley, V.A.2    Kalebic, T.3    Helman, L.4    LeRoith, D.5
  • 27
    • 0029883920 scopus 로고    scopus 로고
    • Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor
    • Hongo A, D'Ambrosio C, Miura M, Morrione A, Baserga R 1996 Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor. Oncogene 12:1231-1238
    • (1996) Oncogene , vol.12 , pp. 1231-1238
    • Hongo, A.1    D'Ambrosio, C.2    Miura, M.3    Morrione, A.4    Baserga, R.5
  • 28
    • 0028921565 scopus 로고
    • Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells
    • Miura M, Li S, Baserga R 1995 Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells. Cancer Res 55:663-667
    • (1995) Cancer Res , vol.55 , pp. 663-667
    • Miura, M.1    Li, S.2    Baserga, R.3
  • 30
    • 0029145296 scopus 로고
    • Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor
    • Miura M, Surmacz E, Burgaud J-L, Baserga R 1995 Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J Biol Chem 270:22639-22644
    • (1995) J Biol Chem , vol.270 , pp. 22639-22644
    • Miura, M.1    Surmacz, E.2    Burgaud, J.-L.3    Baserga, R.4
  • 31
    • 0027402935 scopus 로고
    • Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor: Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (aIR-3)
    • Kato H, Faria TN, Stannard B, Roberts Jr CT, LeRoith D 1993 Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor: characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (aIR-3). J Biol Chem 268:2655-2661
    • (1993) J Biol Chem , vol.268 , pp. 2655-2661
    • Kato, H.1    Faria, T.N.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 32
    • 0027955344 scopus 로고
    • Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
    • Kato H, Faria TN, Stannard B, Roberts Jr CT, LeRoith D 1994 Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol Endocrinol 8:40-50
    • (1994) Mol Endocrinol , vol.8 , pp. 40-50
    • Kato, H.1    Faria, T.N.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 33
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M 1976 A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 34
    • 0026690922 scopus 로고
    • Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells
    • Seger R, Ahn NG, Posada J, Munar ES, Jensen AM, Cooper JA, Cobb MH, Krebs EG 1992 Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. J Biol Chem 267:14373-14381
    • (1992) J Biol Chem , vol.267 , pp. 14373-14381
    • Seger, R.1    Ahn, N.G.2    Posada, J.3    Munar, E.S.4    Jensen, A.M.5    Cooper, J.A.6    Cobb, M.H.7    Krebs, E.G.8
  • 35
    • 0028335994 scopus 로고
    • Insulin-like growth factor-I activation of extracellular signal-related kinase-1 and -2 in growth hormone-secreting cells
    • Webster J, Prager D, Melmed S 1994 Insulin-like growth factor-I activation of extracellular signal-related kinase-1 and -2 in growth hormone-secreting cells. Mol Endocrinol 8:539-544
    • (1994) Mol Endocrinol , vol.8 , pp. 539-544
    • Webster, J.1    Prager, D.2    Melmed, S.3
  • 36
    • 0028332092 scopus 로고
    • Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts
    • Sell C, Dumenil G, Deveaud C, Miura M, Coppola D, DeAngelis T, Rubin R, Efstratiadis A, Baserga R 1994 Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol 14:3604-3612
    • (1994) Mol Cell Biol , vol.14 , pp. 3604-3612
    • Sell, C.1    Dumenil, G.2    Deveaud, C.3    Miura, M.4    Coppola, D.5    DeAngelis, T.6    Rubin, R.7    Efstratiadis, A.8    Baserga, R.9
  • 38
    • 0021221071 scopus 로고
    • Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: Possible role in tumorigenesis
    • Macara IG, Marinetti GV, Balduzzi PC 1984 Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis. Proc Natl Acad Sci USA 81:2728-2732
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 2728-2732
    • Macara, I.G.1    Marinetti, G.V.2    Balduzzi, P.C.3
  • 39
    • 0022197248 scopus 로고
    • Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells
    • Sugimoto Y, Erickson RL 1985 Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells. Mol Cell Biol 5:3194-3198
    • (1985) Mol Cell Biol , vol.5 , pp. 3194-3198
    • Sugimoto, Y.1    Erickson, R.L.2
  • 40
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor I inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways
    • Párrizas M, Saltiel AR, LeRoith D 1997 Insulin-like growth factor I inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J Biol Chem 272:154-161
    • (1997) J Biol Chem , vol.272 , pp. 154-161
    • Párrizas, M.1    Saltiel, A.R.2    LeRoith, D.3
  • 43
    • 0028953268 scopus 로고
    • Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk
    • Beitner-Johnson D, LeRoith D 1995 Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk. J Biol Chem 270:5187-5190
    • (1995) J Biol Chem , vol.270 , pp. 5187-5190
    • Beitner-Johnson, D.1    LeRoith, D.2
  • 44
    • 0028122971 scopus 로고
    • CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells
    • Matsuda M, Hashimoto Y, Moroya K, Hasegawa H, Kurata T, Tanaka S, Nakamura S, Hattori S 1994 CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells. Mol Cell Biol 14:5495-5500
    • (1994) Mol Cell Biol , vol.14 , pp. 5495-5500
    • Matsuda, M.1    Hashimoto, Y.2    Moroya, K.3    Hasegawa, H.4    Kurata, T.5    Tanaka, S.6    Nakamura, S.7    Hattori, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.