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Volumn 137, Issue 2, 1996, Pages 410-417

Tumorigenic and Mitogenic Capacities Are Reduced in Transfected Fibroblasts Expressing Mutant Insulin-Like Growth Factor (IGF)-I Receptors. The Role of Tyrosine Residues 1250, 1251, and 1316 in the Carboxy-Terminus of the IGF-I Receptor

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; INSULIN RECEPTOR; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR;

EID: 0030064571     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.2.8593783     Document Type: Article
Times cited : (69)

References (19)
  • 2
    • 0027170056 scopus 로고
    • Mutational anlysis of insulin receptor function: Consensus and controversy
    • Tavare JM, Siddle K 1993 Mutational anlysis of insulin receptor function: consensus and controversy. Biochim Biophys Acta 1178: 21-39
    • (1993) Biochim Biophys Acta , vol.1178 , pp. 21-39
    • Tavare, J.M.1    Siddle, K.2
  • 3
    • 0027453779 scopus 로고
    • Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions
    • Liu D, Zong CS, Wang L-H 1993 Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions. J Virol 67:6835-6840
    • (1993) J Virol , vol.67 , pp. 6835-6840
    • Liu, D.1    Zong, C.S.2    Wang, L.-H.3
  • 4
    • 0026739799 scopus 로고
    • Antipeptide antibody to the insulin-like growth factor-I receptor sequence 1232-1246 inhibits the receptor kinase activity
    • Kaliman P, Baron V, Gautier N, Van Obberghen E 1992 Antipeptide antibody to the insulin-like growth factor-I receptor sequence 1232-1246 inhibits the receptor kinase activity. J Biol Chem 267: 10645-10651
    • (1992) J Biol Chem , vol.267 , pp. 10645-10651
    • Kaliman, P.1    Baron, V.2    Gautier, N.3    Van Obberghen, E.4
  • 6
    • 0025999981 scopus 로고
    • The carboxyl-terminal domain of the insulin receptor: Its potential role in growth-promoting effects
    • Baron V, Gautier N, Kaliman P, Dolais-Kitabgi J, Van Obberghen E 1991 The carboxyl-terminal domain of the insulin receptor: its potential role in growth-promoting effects. Biochemistry 30:9365-9370
    • (1991) Biochemistry , vol.30 , pp. 9365-9370
    • Baron, V.1    Gautier, N.2    Kaliman, P.3    Dolais-Kitabgi, J.4    Van Obberghen, E.5
  • 7
    • 0027769651 scopus 로고
    • Deletion of C-terminal 113 amino acids impairs processing and internalization of human insulin receptor: Comparison of receptors expressed in CHO and NIH-3T3 cells
    • Levy-Toledano R, Accili D, Taylor SI 1993 Deletion of C-terminal 113 amino acids impairs processing and internalization of human insulin receptor: comparison of receptors expressed in CHO and NIH-3T3 cells. Biochim Biophys Acta 1220:1-14
    • (1993) Biochim Biophys Acta , vol.1220 , pp. 1-14
    • Levy-Toledano, R.1    Accili, D.2    Taylor, S.I.3
  • 8
    • 0022494971 scopus 로고
    • Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
    • Ellis L, Clauser E, Morgan DO, Edery M, Roth RA, Rutter WJ 1986 Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell 45:721-732
    • (1986) Cell , vol.45 , pp. 721-732
    • Ellis, L.1    Clauser, E.2    Morgan, D.O.3    Edery, M.4    Roth, R.A.5    Rutter, W.J.6
  • 9
    • 0027202107 scopus 로고
    • Normal insulin receptor substrate-1 phosphorylation in autophosphorylation-defective truncated insulin receptor. Evidence that phosphorylation of substrates might be sufficient for certain biological effects evoked by insulin
    • Yamamoto-Honda R, Kadowaki T, Momomura K, Tobe K, Tamori Y, Shibasaki Y, Mori Y, Kaburagi Y, Koshio O, Akanuma Y, Yazaki Y, Kasuga M 1993 Normal insulin receptor substrate-1 phosphorylation in autophosphorylation-defective truncated insulin receptor. Evidence that phosphorylation of substrates might be sufficient for certain biological effects evoked by insulin. J Biol Chem 268:16859-16865
    • (1993) J Biol Chem , vol.268 , pp. 16859-16865
    • Yamamoto-Honda, R.1    Kadowaki, T.2    Momomura, K.3    Tobe, K.4    Tamori, Y.5    Shibasaki, Y.6    Mori, Y.7    Kaburagi, Y.8    Koshio, O.9    Akanuma, Y.10    Yazaki, Y.11    Kasuga, M.12
  • 10
    • 0028337291 scopus 로고
    • Insulin receptor autophosphorylation and exogenous substrate phosphorylation: Role of receptor C-terminus and effects of mild reduction
    • Clark S, Konstantopoulos N 1994 Insulin receptor autophosphorylation and exogenous substrate phosphorylation: Role of receptor C-terminus and effects of mild reduction. Biochem Biophys Res Commun 200:330-337
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 330-337
    • Clark, S.1    Konstantopoulos, N.2
  • 11
    • 0028214152 scopus 로고
    • Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptors in receptor function
    • Faria TN, Blakesley VA, Kato H, Stannard B, LeRoith D, Roberts Jr CT 1994 Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptors in receptor function. J Biol Chem 269:13922-13928
    • (1994) J Biol Chem , vol.269 , pp. 13922-13928
    • Faria, T.N.1    Blakesley, V.A.2    Kato, H.3    Stannard, B.4    LeRoith, D.5    Roberts Jr., C.T.6
  • 12
    • 0028346382 scopus 로고
    • Signal transduction by a chimeric insulin-like growth factor-I (IGF-I) receptor having the carboxyl-terminal domain of the insulin receptor
    • Tartare S, Mothe I, Kowalski-Chauvel A, Breittmayer J-P, Ballotti R, Van Obberghen E 1994 Signal transduction by a chimeric insulin-like growth factor-I (IGF-I) receptor having the carboxyl-terminal domain of the insulin receptor. J Biol Chem 269:11449-11455
    • (1994) J Biol Chem , vol.269 , pp. 11449-11455
    • Tartare, S.1    Mothe, I.2    Kowalski-Chauvel, A.3    Breittmayer, J.-P.4    Ballotti, R.5    Van Obberghen, E.6
  • 13
    • 0027402935 scopus 로고
    • Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor: Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (αIR-3)
    • Kato H, Faria TN, Stannard B, Roberts Jr CT, LeRoith D 1993 Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor: characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (αIR-3). J Biol Chem 268:2655-2661
    • (1993) J Biol Chem , vol.268 , pp. 2655-2661
    • Kato, H.1    Faria, T.N.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 14
    • 0028893184 scopus 로고
    • Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function
    • Blakesley VA, Kato H, Roberts Jr CT, LeRoith D 1995 Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function. J Biol Chem 270:2764-2769
    • (1995) J Biol Chem , vol.270 , pp. 2764-2769
    • Blakesley, V.A.1    Kato, H.2    Roberts Jr., C.T.3    LeRoith, D.4
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T 1983 Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot F, Lang R 1986 Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 89:271-277
    • (1986) J Immunol Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 17
    • 0019061918 scopus 로고
    • Ligand: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Rodbard D 1980 Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 18
    • 0028265209 scopus 로고
    • Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant
    • Prager D, Li H-L, Asa S, Melmed S 1994 Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant. Proc Natl Acad Sci USA 91:2181-2185
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2181-2185
    • Prager, D.1    Li, H.-L.2    Asa, S.3    Melmed, S.4
  • 19
    • 0029145296 scopus 로고
    • Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor
    • Miura M, Surmacz E, Burgaud J-L, Baserga R 1995 Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J Biol Chem 270:22639-22644
    • (1995) J Biol Chem , vol.270 , pp. 22639-22644
    • Miura, M.1    Surmacz, E.2    Burgaud, J.-L.3    Baserga, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.