RET proto-oncogene is important for the development of respiratory CO2 sensitivity

Journal of the Autonomic Nervous System

Volumn 63, Issue 3, 1997, Pages 137-143

  Burton, Melvin D ^a   Kawashima, Akira ^a   Brayer, James A ^b   Kazemi, Homayoun ^a   Shannon, Daniel C ^a   Schuchardt, Anita ^d   Costantini, Frank ^d   Pachnis, Vassilis ^c   Kinane, T Bernard ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d Columbia University ^*  (United States)

Author keywords

Control of respiration; Genetics; Knockout mouse; Respiratory chemosensitivity; Ret proto oncogene

Indexed keywords

CARBON DIOXIDE;

ANIMAL EXPERIMENT; ARTICLE; BREATHING; CHEMOSENSITIVITY; CHOLINERGIC SYSTEM; CONTROLLED STUDY; GENOTYPE; HYPERCAPNIA; HYPOTHESIS; HYPOXIA; INHALATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE;

ANIMALS; ANIMALS, NEWBORN; AUTONOMIC NERVOUS SYSTEM; CARBON DIOXIDE; CHEMORECEPTORS; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; RESPIRATION;

EID: 0030993331     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(97)00002-7     Document Type: Article

References (33)

1. M.D. Burton, K. Nouri, S. Baichoo, N. Samuels-Toyloy, H. Kazemi, Ventilatory output and acetylcholine: perturbations in release and muscarinic receptor activation, J. Appl. Physiol. 77 (1994) 2275-2284.
2. M.D. Burton, D.C. Johnson, H. Kazemi, CSF acidosis augments ventilation through cholinergic mechanisms, J. Appl. Physiol. 66 (1989) 2565-2572.
3. M.D. Burton, M. Nouri, H. Kazemi, Acetylcholine and central respiratory control: perturbations of acetylcholine synthesis in the isolated brain stem of the neonatal rat, Brain Res. 670 (1995) 39-47.
4. G.J. Eden, M.A. Hanson, Maturation of the respiratory response to acute hypoxia in the newborn rat, J. Physiol. 392 (1987) 1-9.
5. P. Edery, S. Lyonnet, L.M. Mulligan, A. Pelet, E. Dow, L. Abel, S. Holder, C. Nihoul-Fekete, B.A. Ponder, A. Munnich, Mutations of the RET proto-oncogene in Hirschsprung's disease, Nature 367 (1994) 378-380.
6. J.J. Filiano, H.C. Kinney, Arcuate nucleus hypoplasia in the sudden infant death syndrome, J. Neuropathol. Exp. Neurol. 51 (1992) 394-403.
7. P.J. Fleming, R. Gilbert, Y. Azaz, P.J. Berry, P.T. Rudd, A. Stewart and E. Hall, Interaction between bedding and sleeping position in the sudden infant death syndrome: a population based case-control study, BMJ. 301, 85-89.
8. H. Folgering, F. Kuyper, J.F. Kille, Primary alveolar hypoventilation (ondine's curse syndrome) in an infant without external arcuate nucleus, Bull. Eur. Physiopathol. Respir. 15 (1979) 659-665.
9. G.G. Haddad, N.M. Mazza, R. Defendini, W.A. Blanc, J.M. Driscoll, M.A. Epstein, R.A. Epstein, R.B. Mellins, Congenital failure of automatic control of ventilation, gastrointestinal motility and heart rate, Medicine 57 (1978) 517-526.
10. R.M. Hofstra, R.M. Landsvater, I. Ceccherini, R.P. Stulp, T. Stelwagen, Y. Luo, B. Pasini, J.W. Hoppener, H.K. van Amstel, G. Romeo et al., A mutation in the RET proto-oncogene associated with multiple endocrine neoplaia type 2B and sporadic medullary thyroid carcinoma, Nature 367 (1994) 375-376.
11. A.H. Jansen, V. Chernick, Fetal breathing and development of control of breathing, J. Appl. Physiol. 70 (1991) 1431-1446.
12. S. Jing, D. Wen, Y. Yu, P.L. Holst, Y. Luo, M. Fang, R. Tamir, L. Antonio, Z. Hu, R. Cupples, J.C. Louis, S. Hu, B.W. Altrock, G.M. Fox, GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-a, a novel receptor for GDNF, Cell 85 (1996) 1113-1124.
13. J.S. Kemp and B.T. Thach, Sudden death in infants sleeping on polystyrene-filled cushions, N. Engl. J. Med. 324, 1858-1864.
14. J.S. Kemp, R.M. Kowalski, P.M. Burch, M.A. Graham, B.T. Thach, Unintentional suffocation by rebreathing: a death scene and physiologic investigation of a possible cause of sudden infant death, J. Pediatr. 122 (1993) 874-880.
15. K.C. Kinney, J.J. Filiano, L.A. Sleeper, F. Mandell, D.M. Valdes, W.F. White, Decreased muscarinic receptor binding in the arcuate nucleus in sudden infant death syndrome, Science 269 (1995) 1446-1450.
16. D. Kholwadwala, D.F. Donnelly, Maturation of carotid chemoreceptor sensitivity to hypoxia: in vitro studies in the newborn rat, J. Physiol. 453 (1992) 461-473.
17. S. Lyonnet, A. Bolino, A. Pelet, L. Abel, C. Nihoul-Fekete, M.L. Briard, V. Mok-Siu, H. Kaariainen, G. Martucciello, M. Lerone et al., A gene for Hirschsprung diease maps to the proximal long arm of chromosome 10, Nature Genetics 4 (1993) 346-350.
18. C. Minutillo, P.J. Pemberton, J. Goldblatt, Hirschsprung's disease and Ondine's curse: further evidence for a distinct syndrome, Clin. Genet. 36 (1989) 200-203.
19. J.P. Mortola, Breathing pattern in newborns, J. Appl. Physiol. 56 (1984) 1533-1540.
20. I.R. Moss, J.G. Inman, Neurochemicals and respiratory control during development, J. Appl. Physiol. 67 (1989) 1-13.
21. L.M. Mulligan, J.B. Kwok, C.S. Healey, M.J. Elsdon, C. Eng, E. Gardner, D.R. Love, S.E. Mole, J.K. Moore, L. Papi et al., Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A, Nature 363 (1993) 458-460.
22. J. Oren, C.J. Newth, C.E. Hunt, R.T. Brouillette, R.T. Bachand, D.C. Shannon, Ventilatory effects of almitrine bismesylate in congenital central hypoventilation syndrome, Amer. Rev. Respir. Dis. 134 (1986) 917-919.
23. V. Pachnis, B. Mankoo, F. Costantini, Expression of the c-ret proto-oncogene during mouse embryogenesis, Development 119 (1993) 1005-1017.
24. A.L. Ponsonby, T. Dwyer, L.E. Gibbons, J.A. Cochrane, Y.G. Wang, Factors potentiating the risk of sudden infant death syndrome associated with the prone position, N. Engl. J. Med. 329 (1993) 377-382.
25. G. Romeo, P. Ronchetto, Y. Luo, V. Barone, M. Seri, I. Ceccherini, B. Pasini, R. Bocciardi, M. Lerone, H. Kaariainen et al., Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease, Nature 367 (1994) 377-378.
26. B. Rosner, Fundamentals of Biostatistics, 4th Ed. Chapter 8, International Thomson Publishing, London, 1995.
27. A. Schuchardt, V. D'Agati, L. Larsson-Blomberg, F. Costantini, V. Pachnis, Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret, Nature 367 (1994) 380-383.
28. D.C. Shannon, D. Kelly, Impaired regulation of alveolar ventilation and sudden infant death syndrome, Science 197 (1977) 367-368.
29. D.C. Shannon, D.W. Marsland, J.B. Gould, B. Callahan, I.D. Todres, J. Dennis, Central hypoventilation during quiet sleep in two infants, Pediatrics 57 (1976) 342-346.
30. T. Tahira, Y. Ishizaka, T. Sugimura, M. Nagao, Expression of proto-ret mRNA in embryonic and adult rat tissues, Biochem. Biophys. Res. Comm. 153 (1988) 1290-1295.
31. V. Van Heyningen, One gene-four syndromes, Nature 367, 319-320.
32. M.S. Woo, M.A. Woo, D. Gozal, M.T. Jansen, T.G. Keens, R.M. Harper, Heart rate variability in congenital central hypoventilation syndrome, Pediatr. Res. 31 (1992) 291-296.
33. F. Yasuma, H. Nomura, I. Sotobata, H. Ishihara, H. Saito, K. Yasuura, H. Okamoto, S. Hirose, T. Abe, A. Seki, Congenital central alveolar hypoventilation (Ondine's curse): a case report and review of the literature, Eur. J. Pediatr. 146 (1987) 81-83.