The biological exposure indices: A key component in protecting workers from toxic chemicals

Environmental Health Perspectives

Volumn 105, Issue SUPPL. 1, 1997, Pages 105-115

  Morgan, Michael S ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Department of Environmental Health ^*  (United States)

Author keywords

ACGIH; Biological monitoring; Biomarkers; Exposure assessment; Industrial hygiene; Reference values

Indexed keywords

AIR MONITORING; AMBIENT AIR; BIOLOGICAL MONITORING; HUMAN; INDUSTRIAL HYGIENE; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; REFERENCE VALUE; REVIEW; TOXICOKINETICS;

EID: 0030990581     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.97105s1105     Document Type: Review

References (63)

1. Lowry L. Biological exposure index as a complement to the TLV. J Occup Med 28(8):578-582 (1986).
2. Lauwerys R, Hoet P. Industrial Chemical Exposure: Guidelines for Biological Monitoring. 2nd ed. Boca Raton, FL:Lewis Publishers, 1993;318.
3. Zielhuis R. Biological Monitoring: Guest lecture given at the 26th Nordic Symposium on Industrial Hygiene. Scand J Work Environ Health 4(1):1-18 (1978).
4. Zielhuis R. General aspects of biological monitoring. In: The Use of Biological Specimens for the Assessment of Human Exposure to Environmental Pollutants (Berlin A, Wolff A, Hasegawa Y, eds). The Hague:Martinus Nijhoff, 1979:341-359.
5. ACGIH. Threshold Limit Values (TLVs) for Chemical Substances and Physical Agents and Biological Exposure Indices (BEIs). Cincinnati, OH:American Conference of Governmental Industrial Hygienists, 1996;56.
6. Bardodej Z, Urban J, Malonova H. Important considerations in the development of biological monitoring methods to determine occupational exposure to organic chemicals. In: Biological Monitoring of Exposure to Chemicals (Ho M, Dillon H, eds). New York:John Wiley & Sons, 1987;17-28.
7. Lowry L. Biological limit values. In: Methods for Biological Monitoring (Kneip T, Crable J, eds). Washington:American Public Health Association, 1988;109-119.
8. Elkins H. Analyses of biological material as indices of exposure to organic solvents. Arch Ind Hyg Occup Med 9:212-222 (1954).
9. Elkins H. Excretory and biologic threshold limits. Amer Ind Hyg Assoc J 28:305 (1967).
10. Mastomatteo E. TLVs: changes in philosophy. Appl Ind Hyg 3(3):F12-F16 (1988).
11. Murthy L, Halperin W. Medical screening and biological monitoring: a guide to the literature for physicians. J Occup Environ Med 37(2):170-184 (1995).
12. ACGIH. Documentation of the Threshold Limit Values and Biological Exposure Indices, Vol III. 6th ed. Cincinnati, OH:American Conference of Governmental Industrial Hygienists, 1991.
13. Williamson A, Teo R. Neurobehavioral effects of occupational exposure to lead. Br J Ind Med 43:374-380 (1986).
14. Hirata M, Kosaka H. Effects of lead exposure on neuropsychological parameters. Environ Res 63:60-69 (1993).
15. Grandjean P. Effects in reserve capacity: significance for exposure limits. Sci Total Environ 101:25-32 (1991).
16. Staessen J, Lauwerys R, Buchet J-P. Impairment of renal function with increasing blood lead concentrations in the general population. N Engl J Med 327:151-156 (1992).
17. Factor-Litvak P, Stein Z, Graziano J. Increased risk of proteinuria among a cohort of lead-exposed pregnant women. Environ Health Perspect 101(5):418-421 (1993).
18. Lindbohm M-L, Sallmen M, Anttila A. Paternal occupational lead exposure and spontaneous abortion. Scand J Work Environ Health 17:95-103 (1991).
19. Assenato G, Paci C, Molini R. Sperm count suppression without endocrine dysfunction in lead-exposed men. Arch Environ Health 41(6):387-390 (1986).
20. Andrews K, Savitz D, Hertz-Picciotto I. Prenatal lead exposure in relation to gestational age and birth weight: a review of epidemiologic studies. Amer J Ind Med 26:13-32 (1994).
21. Foo S, Jeyaratnam J, Ong C, Khoo N, Koh D, Chia S. Biological monitoring for occupational exposure to toluene. Amer Ind Hyg Assoc J 52(5):212-217 (1991).
22. DeRosa E, Cellini M, Sessa G, Scapellato M, Marcuzzo G, Bartolucci G. The importance of sampling time and coexposure to acetone in the biological monitoring of styrene-exposed workers. Appl Occup Environ Hyg 11(5):471-475 (1996).
23. DeRosa E, Brugnone F, Bartolucci G. The validity of urinary metabolites as indicators of low exposures to toluene. Int Arch Occup Environ Health 56:135-145 (1985).
24. Hasegawa K, Shiojima S, Koizumi A. Hippuric acid and o-cresol in the urine of workers exposed to toluene. Int Arch Occup Environ Health 52:197-208 (1983).
25. Ogata M, Taguchi T. Simultaneous determination of urinary creatinine, and metabolites of toluene, xylene, styrene, ethyl benzene and phenol by automated high-performance liquid chromatography. Int Arch Occup Environ Health 61:131-140 (1988).
26. Foster P, Lloyd S, Blackburn D. Comparison of the in vivo and in vitro testicular effects produced by methoxy-, ethoxy-, and n-butoxy acetic acids in the rat. Toxicology 43:17-30 (1987).
27. Wittfoht W, Scott W, Nau H. Assay of methoxyacetic acid in body fluids and tissues by gas chromatography-mass spectroscopy following tert-butyldimethylsilation. J Chromarog 448:433-438 (1988).
28. Dugard P. Absorption of some glycol ethers through human skin in vitro. Environ Health Perspect 57:193-197 (1984).
29. Sparer J, Welch L, McManus K. Effects of exposure to ethylene glycol ethers on shipyard painters. I: Evaluation of exposure. Amer J Ind Med 14:497-507 (1988).
30. Van Damme K, Casteleyn L, Heseltine E, Huici A, Sorsa M, van Larebeke N, Vineis P. Individual susceptibility and prevention of occupational diseases: scientific and ethical issues. J Occup Environ Med 37(1):91-99 (1995).
31. Hulka B, Wilcosky T. Biological markers in epidemiologic research. Arch Environ Health 43(2):83-89 (1988).
32. Friberg L, Elinder C-G. Biological monitoring of toxic metals. Scand J Work Environ Health 19(Suppl 1):7-13 (1993).
33. Aitio A. Biological monitoring at the Institute of Occupational Health. Scand J Work Environ Health 18(Suppl 2):69-71 (1992).
34. Bernard A, Lauwerys R. Present status and trends in biological monitoring of exposure to industrial chemicals. J Occup Med 28(8):558-562 (1986).
35. Greim H, Csanady G, Filser J, Kreuzer P, Schwarz L, Wolff T, Werner S. Biomarkers as tools in human health risk assessment. Clin Chem 41(12):1804-1808 (1995).
36. Vainio H. Current trends in the biological monitoring of exposure to carcinogens. Scand J Work Environ Health 11(1):1-6 (1985).
37. Aitio A. Biological monitoring today and tomorrow. Scand J Work Environ Health 20(Special issue):46-58 (1994).
38. Lehnen G, Schaller K-H. Strategy of biological monitoring and setting of biological threshold limits (BAT values) in Germany. Isr J Med Sci 31 (9):549-557 (1995).
39. Sherwood R. Benzene: the interpretation of monitoring results. Ann Occup Hyg 15:409-421 (1972).
40. Biological Exposure Values for Occupational Toxicants and Carcinogens, Vol 2 (Greim H, Lehnert G, ed). Weinheim, Germany:VCH Verlagsgesellschaft, 1995;221.
41. Talaska G, Schamer M, Skipper P, Tannenbaum S, Caporaso N, Kadlubar F, Bartsch H, Vineis P. Carcinogen-DNA adducts in exfoliated urothelial cells: techniques for noninvasive human monitoring. Environ Health Perspect 99:289-291 (1993).
42. Hemminki K. DNA adducts in biomonitoring. J Occup Environ Med 37(1):44-51 (1995).
43. Anderson D, Legator M. Practical issues in the evaluation of monitoring techniques: need for validation, quality assurance and establishment of baseline values. In: Monitoring Human Exposure to Carcinogenic and Mutagenic Agents (Berlin A, Draper M, Hemminki K, Vainio H, eds). Lyon:International Agency for Research on Cancer 431-433 (1984).
44. Thomas V. Five years of the biological exposure indices committee. Appl Ind Hyg 3(10):F26-F28 (1988).
45. Ashford N. Policy considerations for human monitoring in the workplace. J Occup Med 28(8):563-568 (1986).
46. Droz P. Sources of variability in human response to chemical exposure. Appl Ind Hyg 4(1):F20-F24 (1989).
47. Droz P, Wu M, Cumberland W. Variability in biological monitoring of organic solvent exposure. II: Application of a population physiological model. Br J Ind Med 46(8):547-558 (1989).
48. Droz P, Wu M, Cumberland W, Berode M. Variability in biological monitoring of solvent exposure. I: Development of a population physiological model. Br J Ind Med 46:447-460 (1989).
49. Thomas R, Bigelow P, Keefe T, Yang R. Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation. Am Ind Hyg Assoc J 57(1):23-32 (1996).
50. Vesterberg O, Alessio L, Brune D, Gerhardsson L, Herber R, Kazantzis G, Nordberg G, Sabbioni E. International project for producing reference values for concentrations of trace elements in human blood and urine - TRACY. Scand J Work Environ Health 19(Suppl 1):19-26 (1993).
51. Vanden-Heuvel J, Clark G, Thompson C, McCoy Z, Miller C, Lucier G, Bell D. CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. Carcinogenesis 14(10):2003-2006 (1993).
52. Kawamoto T, Koga M, Murata K, Masuda S, Kodama Y. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans. Toxicol Appl Pharmacol 133:295-304 (1995).
53. Hirvonen A. Genetic factors in individual responses to environmental exposures. J Occup Environ Med 37(1):37-43 (1995).
54. Ellis K. In vivo monitoring techniques. In: Methods for Biological Monitoring (Kneip T, Crable J, eds). Washington: American Public Health Association, 1988;65-80.
55. Droz P, Guillemin M. Occupational exposure monitoring using breath analysis. J Occup Med 28(8):593-602 (1986).
56. Lu C-S, Fenske R, Anderson L. Determination of atrazine levels in whole saliva and plasma in rats: potential of salivary monitoring for occupational exposure. J Toxicol Environ Health 50:101-111 (1997).
57. White M, O'Hagan S, Wright A, Wilson H. The measurement of salivary cadmium by electrothermal atomic absorption spectrophotometry and its use as a biological indicator of occupational exposure. J Expos Anal Environ Epid 2(2):195-206 (1992).
58. Woollen B. Biological monitoring for pesticide absorption. Ann Occup Hyg 37(5):525-540 (1993).
59. Mendelsohn M. The current applicability of large scale biomarker programs to monitor cleanup workers. In: Biomarkers and Occupational Health: Progress and Perspectives (Mendelsohn M, Peelers J, Normandy M, eds). Washington: John Henry Press, 1995;9-19.
60. Samuels S. Medical surveillance: biological, social and ethical parameters. J Occup Med 28(8):572-577 (1986).
61. Takebayashi T, Omae K, Sherwood R. A comparison of U.S. and Japanese occupational exposure limits for chemical substances and biological monitoring values. Appl Occup Environ Hyg 11(5):457-462 (1996).
62. Toyama T. Permissible and control limits of toxic substances at places of work in Japan. Am J Ind Med 8:87-89 (1985).
63. Fowler B, Friberg L. Reference values for the biological monitoring of trace elements in environmental and occupational health. Scand J Work Environ Health 19(Suppl 1):65-66 (1993).