Protein tyrosine kinase activity regulates nitric oxide synthase induction in rat hepatocytes

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 2 35-2, 1997, Pages

  Miller, Danette R ^a   Collier, John M ^a   Billings, Ruth E ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

interleukin 1 ; phorbol 12 myristate 13 acetate; tumor necrosis factor; xanthine oxidase

Indexed keywords

GENISTEIN; INTERLEUKIN 1BETA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN TYROSINE KINASE; TUMOR NECROSIS FACTOR ALPHA; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; INFLAMMATION; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION REGULATION;

EID: 0030988577     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.2.g207     Document Type: Article

References (35)

1. Adcock, I. M., C. R. Brown, O. Kwon, and P. J. Barnes. Oxidative stress induces NF-κB DNA binding and inducible NOS mRNA in human epithelial cells. Biochem. Biophys. Res. Commun. 199: 1518-1524, 1994.
2. Bird, T. A., J. M. Kyriakis, L. Tyshler, M. Gayle, A. Milne, and G. D. Virca. Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21 ras, Raf-1, and MAP kinase kinase. J. Biol. Chem. 269: 31836-31844, 1994.
3. Carlson, T. J., and R. E. Billings. The role of nitric oxide in the cytokine-mediated regulation of cytochrome P450. Mol. Pharmacol. 49: 796-801, 1996.
4. Corbett, J. A., G. Kwon, T. P. Misko, C. P. Rodi, and M. L. McDaniel. Tyrosine kinase involvement in IL-1β-induced expression of iNOS by β-cells purified from islets of Langerhans. Am. J. Physiol. 267 (Cell. Physiol. 36): C48-C54, 1994.
5. Curran, R. D., F. K. Ferrari, P. H. Kispert, J. Stadler, D. J. Stuehr, R. L. Simmons, and T. R. Billiar. Nitric oxide and nitric oxide-generating compounds inhibit hepatocyte protein synthesis. FASEB J. 5: 2085-2092, 1991.
6. Davis, R. J. MAPKs: new jnk expands the group. Trends Biochem. Sci. 19: 470-473, 1994.
7. Dong, Z., X. Qi, K. Xie, and I. J. Fidler. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophage. J. Immunol. 151: 2717-2724, 1993.
8. Duval, D. L., D. R. Miller, J. M. Collier, and R. E. Billings. Characterization of hepatic nitric oxide synthase: identification as the cytokine-inducible form primarily regulated by oxidants. Mol. Pharmacol. 50: 277-284, 1996.
9. Duval, D. L., D. J. Sieg, and R. E. Billings. Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione. Arch. Biochem. Biophys. 316: 699-706, 1995.
10. Feinstein, D. L., E. Galea, and D. J. Reis. Suppression of glial iNOS expression by tyrosine kinase inhibitors. Ann. NY Acad. Sci. 738: 325-328, 1994.
11. 1-Integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor. J. Cell Biol. 127: 1477-1483, 1994.
12. Garcia-Ruiz, C., A. Colell, A. Morales, N. Kaplowitz, and J. C. Fernandez-Checa. Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-κB: studies with isolated mitochondria and rat hepatocytes. Mol. Pharmacol. 48: 825-834, 1995.
13. Geller, D. A., A. K. Kussler, M. DiSilvio, C. J. Lowenstein, R. A. Shapiro, S. C. Wang, R. L. Simmons, and T. R. Billiar. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc. Natl. Acad. Sci. USA 90: 522-526, 1993.
14. Geller, D. A., M. E. de Vera, D. A. Russell, R. A. Shapiro, A. K. Nussler, R. L. Simmons, and T. R. Billiar. A central role for IL-1β in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. J. Immunol. 155: 4890-4898, 1995.
15. Guy, G. R., S. P. Chua, N. S. Wong, S. B. Ng, and Y. H. Tan. Interleukin 1 and tumor necrosis factor activate common multiple protein kinases in human fibroblasts. J. Biol. Chem. 266: 14343-14352, 1991.
16. Hortelano, S., A. M. Genaro, and L. Bosca. Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. J. Biol. Chem. 267: 24937-24940, 1992.
17. Joshi-Barve, S. S., V. V. Rangnekar, S. F. Sells, and V. M. Rangnekar. Interleukin-1-inducible expression of gro-β via NF-κB activation dependent on tyrosine kinase signaling. J. Biol. Chem. 268: 18018-18029, 1993.
18. Kohno, M., N. Nishizawa, M. Tsujimoto, and H. Nomoto. Mitogenic signalling pathway of tumor necrosis factor involves the rapid phosphorylation of 41,000-M and 43,000-M cytosol proteins. Biochem. J. 267: 91-98, 1990.
19. Kroncke, K. D., K. Fehsel, and V. Kolb-Bachofen. Inducible nitric oxide synthase and its product nitric oxide, a small molecule with complex biological activities. Biol. Chem. Hoppe-Seyler 376: 327-343, 1995.
20. Lowenstein, C. J., E. W. Alley, P. Raval, A. M. Snowman, S. H. Snyder, S. W. Russell, and W. J. Murphy. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc. Natl. Acad. Sci. USA 90: 9730-9734, 1993.
21. Meier, B., H. H. Radeke, S. Selle, M. Younes, H. Sies, K. Resch, and G. G. Habermehl. Human fibroblasts release ROI in response to IL-1 and TNFα. Biochem. J. 263: 539-545, 1989.
22. Moncada, S., and A. Higgs. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 329: 2002-2012, 1993.
23. Rafiee, P., J. K. Lee, C. Leung, and T. A. Raffin. TNF-α induces tyrosine phosphorylation of mitogen-activated protein kinase in adherent human neutrophils. J. Immunol. 154: 4785-4792, 1995.
24. Raingeaud, J., S. Gupta, J. S. Rogers, M. Dickens, J. Han, J. R. Ulevitch, and R. J. Davis. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270: 7420-7426, 1995.
25. Saklatvala, J. Intracellular signalling mechanisms of interleukin 1 and tumour necrosis factor: possible targets for therapy. Br. Med. Bull. 51: 402-418, 1995.
26. Saklatvala, J., L. M. Rawlinson, C. J. Marshall, and M. Kracht. Interleukin-1 and tumour necrosis factor activate the mitogen- activated protein (MAP) kinase kinase in cultured cells. FEBS Lett. 334: 189-192, 1993.
27. Schieven, G. L., and J. A. Ledbetter. Activation of tyrosine kinase signal pathways by radiation and oxidative stress. Trends Endocrinol. Metab. 5: 383-388, 1994.
28. Sluss, H. K., T. Barrett, B. Derijard, and R. J. Davis. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol. Cell. Biol. 14: 8376-8384, 1994.
29. Stadler, J., T. R. Billiar, R. D. Curran, D. J. Stuehr, J. B. Ochoa, and R. L. Simmons. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260 (Cell Physiol. 29): C910-C916, 1991.
30. Stadler, J., J. Trockfeld, W. A. Schmalix, T. Brill, J. R. Siewert, H. Grein, and J. Doehmer. Inhibition of cytochrome P4501A by nitric oxide. Proc. Natl. Acad. Sci. USA 91: 3559-3563, 1994.
31. Tetsuka, T., and A. R. Morrison. Protein tyrosine kinase activity is necessary for iNOS expression by IL-1β. Am. J. Physiol. 269 (Cell Physiol. 38): C55-C59, 1995.
32. Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghost. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80: 573-582, 1995.
33. Victor, I., P. Schwenger, W. Li, J. Schlessinger, and J. Vilcek. Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. J. Biol. Chem. 268: 18994-18999, 1993.
34. Westwick, J. K., C. Weitzel, A. Minden, M. Karin, and D. A. Brenner. Tumor necrosis factor-α stimulates AP-1 activity through prolonged activation of the c-jun kinase. J. Biol. Chem. 269: 26396-26401, 1994.
35. Xie, Q., R. Whisnant, and C. Nathan. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide. J. Exp. Med. 177: 1779-1784: 1993.