Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone

Journal of Anatomy

Volumn 191, Issue 1, 1997, Pages 39-48

  Bord, Sharyn ^a,d   Horner, Alan ^a   Hembry, Rosalind M ^b   Reynolds, John J ^c   Compston, Juliet E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Collagenase; Gelatinase; Osteoblasts; Osteoclasts; Stromelysin

Indexed keywords

COLLAGENASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; POLYCLONAL ANTIBODY; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; BONE DEVELOPMENT; BONE TURNOVER; CARTILAGE CELL; CELL PROLIFERATION; CONNECTIVE TISSUE; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOPHYTE; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANIMALIA;

BONE AND BONES; CARTILAGE; COLLAGENASES; GELATINASES; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; PROTEASE INHIBITORS; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 0030986438     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-7580.1997.19110039.x     Document Type: Article

References (40)

1. AIGNER T, DIETZ U, STOB H, VON DER MARK K (1995) Differential expression of collagen types I, II, III and X in human osteophytes. Laboratory Investigation 73, 236-243.
2. r active forms of stromelysin to collagen is mediated by the C-terminal domain. Journal of Cell Science 99, 789-795.
3. BIRKEDAL-HANSEN H, MOORE WGI, BODDEN MK, WINDSOR LJ, BIRKEDAL-HANSEN B, DECARLO A et al. (1993) Matrix metalloproteinase: a review. Critical Reviews in Oral Biological Medicine 4 (2), 197-220.
4. BLUMENTHAL NC, POSNER AS, SILVERMAN LD, ROSENBERG LC (1979) Effect on proteoglycan on in vitro hydroxyapatite formation. Calcified Tissue International 27, 75-82.
5. BORD S, HORNER A, HEMBRY RM, REYNOLDS JJ, COMPSTON JE (1996) Production of collagenase by human osteoblasts and osteoclasts in vivo. Bone 19, 35-40.
6. BRADBEER J, LINDSAY PC, REEVE J (1994) Fluctuation of mineral apposition rate at individual bone remodelling sites in human iliac cancellous bone: independent correlations with ostoid width and osteoblastic alkaline phosphatase activity. Journal of Bone and Mineral Research 9, 1679-1686.
7. BRECKON JJW, HEMBRY RM, REYNOLDS JJ, MEIKLE MC (1995) Matrix metalloproteinases and TIMP-1 localization at sites of osteogenesis in the craniofacial region of the rabbit embryo. Anatomical Record 242, 177-187.
8. BROWN CC, HEMBRY RM, REYNOLDS JJ (1989) Immunolocalisation of metalloproteinases and their inhibitor in the rabbit growth plate. Journal of Bone and Joint Surgery 71A, 580-593.
9. CAWSTON TE (1986) Protein inhibitors of metalloproteinases. In Proteinase Inhibitors (ed. Barrett AJ, Salvesen G), pp. 589-610. Amsterdam: Elsevier.
10. DEAN DD, MUNIZ OE, HOWELL DS (1989) Association of collagenase and tissue inhibitor of metalloproteinases (TIMP) with hypertrophic cell enlargement in the growth plate. Matrix 9, 366-375.
11. DEBARNARD B, STAGNI N, COLAUTTI T, VITTUR F, BONUCCI E (1977) Glycosaminoglycans and endochondral calcification. Clinical Orthopaedics and Related Research 126, 285-291.
12. DELAISSÉ JM, EECKHOUT Y, VAES G (1988) Bone resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue. Endocrinology 123, 264-276.
13. DELAISSÉ JM, EECKHOUT Y, NEFF L, FRANÇOIS-GILLET CH, HENRIET P, Su Y et al. (1993) (Pro)collagenase (matrix metallo-proteinase-1) is present in rodent osteoclasts and in the underlying bone-resorbing compartment. Journal of Cell Science 106, 1071-1082.
14. DODDS RA, GOWEN M (1994) The growing osteophyte: a model system for the study of human bone development and remodelling in situ. Journal of Histotechnology 17, 37-45.
15. DODDS RA, CONNOR JR, JAMES IE, RYKACZEWSKI E, APPELBAUM E, DUL E et al. (1995) Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: an in vitro and ex vivo study of remodeling bone. Journal of Bone and Mineral Research 10, 1666-1680.
16. EVERTS V, DELAISSÉ JM, KORPER W, NEOHOF A, VAES G, BEERTSEN W (1992) Degradation of collagen in the bone resorbing compartment underlying the osteoclast involves both cysteineproteinase and matrix metalloproteinases. Journal of Cell Physiology 150, 221-231.
17. HEATH JK, ATKINSON SJ, MEIKLE MC, REYNOLDS JJ (1984) Mouse osteoblasts synthesize collagenase in response to bone-resorbing agents. Biochimica et Biophysica Acta 802, 151-154.
18. HEMBRY RM, MURPHY G, REYNOLDS JJ (1985) Immunolocalisation of tissue inhibitor of metalloproteinase (TIMP) in human cells. Characterisation and use of a specific antiserum. Journal of Cell Science 73, 105-119.
19. HEMBRY RM, BAGGA MR, REYNOLDS JJ, HAMBLEN DL (1995) Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis. Annals of Rheumatic Diseases 54, 25-32.
20. HILL PA, MURPHY G, DOCHERTY AJP, HEMBRY RM, MILLICAN TA, REYNOLDS JJ (1994) The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. Journal of Cell Science 107, 3055-3064.
21. HIPPS DS, HEMBRY RM, DOCHERTY AJP, REYNOLDS JJ, MURPHY G (1991) Purification and characterisation of human 72-kDa gelatinase (type IV) collagenase. Use of immunolocalisation to demonstrate the non-coordinated regulation of the 72 kDa and 95 kDa gelatinases by human fibroblasts. Biological Chemistry, Hoppe-Seyler, 372, 287-296.
22. KARELINA TV, GOLDBERG GI, EISEN AZ (1995) Matrix metalloproteinases in blood vessel development in human fetal skin and in cutaneous tumors. Journal of Investigative Dermatology 105, 411-417.
23. LOVERIDGE N, DEAN V, GOLTZMAN D, HENDY GN (1991) Bioactivity of parathyroid hormone and parathyroid hormone-like peptide: agonist and antagonist activities of amino-terminal fragments as assessed by the cytochemical bioassay and in situ biochemistry. Endocrinology 128, 1938-1946.
24. MEIKLE MC, MCGARRITY AM, THOMSON BM, REYNOLDS JJ (1991) Bone-derived growth factors modulate collagenase and TIMP (tissue inhibitor of metalloproteinases) activity and type 1 collagen degradation by mouse calvarial osteoblasts. Bone and Mineral 12, 41-55.
25. MEIKLE MC, BORD S, HEMBRY RM, COMPSTON JE, CROUCHER PI, REYNOLDS JJ (1992) Human osteoblasts in culture synthesise collagenase and other matrix metalloproteinases in response to osteotropic hormones and cytokines. Journal of Cell Science 103, 1093-1099.
26. MEIKLE MC, BORD S, HEMBRY RM, REYNOLDS JJ (1995) The synthesis of collagenase, gelatinase-A (72 kDa) and gelatinase-B (95 kDa), and TIMP-1 and TIMP-2 by human osteoblasts from normal and arthritic bone. Bone 17, 255-260.
27. MERRY K, DODDS R, LITTLEWOOD A, GOWEN M (1993) Expression of osteopontin mRNA by osteoclasts and osteoblasts in modelling human bone. Journal of Cell Science 104, 1013-1020.
28. MIDDLETON J, ARNOTT N, WALSH S, BERESFORD J (1995) Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type I IGF receptor. Bone 16, 287-293.
29. MURPHY G, COCKETT MI, STEPHENS PE, SMITH BJ, DOCHERTY AJP (1987) Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes. Biochemical Journal 248, 265-268.
30. MURPHY G, WARD R, HEMBRY RM, REYNOLDS JJ, KUHN K, TRYGGVASON K (1989) Characterization of gelatinase frorri pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase. Biochemical Journal 258, 463-472.
31. MURPHY G, ALLAN JA, WILLENBROCK F, COCKETT MI, O'CONNELL JP, DOCHERTY AJP (1992) The role of the C-terminal domain in collagenase and stromelysin specificity. Journal of Biological Chemistry 267, 9612-9618.
32. MURPHY G, REYNOLDS JJ (1993) Extracellular matrix degradation. In Connective Tissue and Its Heritable Disorders (ed. Royce P, Steinmann B) pp. 287-316. New York: Wiley-Liss.
33. PINCHBACK JS, GIBBINS JR, HUNTER N (1996) Vascular colocalisation of proteolytic enzymes and proteinase inhibitors in advanced periodontitis. Journal of Pathology 179, 326-332.
34. RAINA V (1972) Normal osteoid tissue. Journal of Clinical Pathology 25, 229-232.
35. RAO VH, BRIDGE JA, NEFF JR, SCHAEFER GB, BUEHLER BA, VISHWANATHA JK et al. (1995) Expression of 72 kDa and 92 kDa type IV collagenases from human giant-cell tumour of bone. Clinical and Experimental Metastasis 13, 420-426.
36. RESNICK D, NIWAYAMA G (1995) Degenerative disease of extraspinal locations. In Diagnosis of Bone and Joint Disorders, 3rd edn, vol. 3 (ed. Resnick D), pp 1263-1372. Philadelphia: WB Saunders.
37. STRICKLIN GP, NANNEY LB (1994) Immunolocalization of collagenase and TIMP in healing human burn wounds. Journal of Investigative Dermatology 103, 488-492.
38. WHITHAM SE, MURPHY G, ANGEL P, RAHMSDORP HJ, SMITH BJ, LYONS A et al. (1986) Comparison of human stromelysin and collagenase by cloning and sequence analysis. Biochemical Journal 240, 913-916.
39. WITTY JP, FOSTER SA, STRICKLIN GP, MATISIAN LM, STERN PA (1996) Parathyroid hormone-induced resorption in fetal rat limb bones is associated with production of the metalloproteinases collagenase and gelatinase-B. Journal of Bone and Mineral Research 11, 72-78.
40. WUCHERPFENNIG AL, LI Y-P, STETLER-STEVENSON WG, ROSENBURG AE, STASHENKO P (1994) Expression of 92 kD type IV collagenase/gelatinase B in human osteoclasts. Journal of Bone and Mineral Research 9, 549-556.