Production of collagenase by human osteoblasts and osteoclasts in vivo

Bone

Volumn 19, Issue 1, 1996, Pages 35-40

  Bord, S ^a   Horner, A ^a   Hembry, R M ^b   Reynolds, J J ^c   Compston, J E ^a,d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Bone remodeling; Collagenase; Metalloproteinases; Osteoblasts; Osteoclasts

Indexed keywords

COLLAGENASE; METALLOPROTEINASE;

ARTICLE; BONE EROSION; BONE MATRIX; BONE REMODELING; BONE TURNOVER; ECTOPIC TISSUE; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MONONUCLEAR CELL; NORMAL HUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PROTEIN EXPRESSION;

EID: 0029845733     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/8756-3282(96)00106-8     Document Type: Article

References (32)

1. Case, J. P., Sano, H., Lafyatis, R., Remmers, E. F., Kumkumian, G. K., and Wilder, R. L. Transin/stromelysin expression in the synovium of rats with experimental erosive arthritis. In situ localization and kinetics of expression of the transformation-associated metalloproteinase in euthymic and athymic Lewis rats. J Clin Invest 84:1731-1740; 1989.
2. Chambers, T. J. and Fuller, K. Bone cells predispose bone surfaces to resorption by exposure of mineral to osteoclastic attack. J Cell Sci 76:155-165; 1985.
3. Chow, J. and Chambers, T. J. An assessment of the prevalence of organic material on bone surfaces. Calcif Tissue Int 50:118-122; 1992.
4. Clark, I. M., Wright, J. K., Cawston, T. E., and Hazleman, B. L. Polyclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunoabsorbent assay to measure TIMP-collagenase complex. Matrix 12:108-115; 1992.
5. Croucher, P. I. and Compston, J. E. Histomorphometric assessment of trabecular bone remodeling in osteoporosis. Bone Miner 14:91-102; 1991.
6. Dean, D. D., Muniz, O. E., and Howell, D. S. Association of collagenase and tissue inhibitor of metalloproteinases (TIMP) with hypertrophic cell enlargement in the growth plate. Matrix 9:366-375; 1989.
7. Delaissé, J. M., Eeckhout, Y., Neff, L., Francois-Gillet, Ch., Henriet, P., Su, Y., Vaes, G., and Baron, R. (Pro)collagenase (matrix metalloproteinase-1) is present in rodent osteoclasts and in the underlying bone-resorbing compartment. J Cell Sci 106:1071-1082; 1993.
8. Delaissé, J. M., Eeckhout, Y., Sear, C., Galloway, A., McCullagh, K., and Vaes, G. A new synthetic inhibitor of mammalian tissue collagenase inhibits bone resorption in culture. Biochem Biophys Res Commun 133:483-490; 1985.
9. 3H-tetracycline retention in bones of prelabelled mice. Bone 12:289; 1991.
10. Delaissé, J. M., Eeckhout, Y., and Vaes, G. Bone resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue. Endocrinology 123:264-276; 1988.
11. Dodds, R. A. and Gowen, M. The growing osteophyte: A model system for the study of human bone development and remodeling in situ. J Histotech 17:37-45; 1994.
12. Everts, V., Delaissé, J. M., Korper, W., Neohof, A., Vaes, G., and Beertsen, W. Degradation of collagen in the bone resorbing compartment underlying the osteoclast involves both cysteine-proteinases and matrix metalloproteinases. J Cell Physiol 150:221-231; 1992.
13. Fuller, K. and Chambers, T. J. Localization of mRNA in osteocytic, bone surface, and chondrocytic cells but not osteoclasts. J Cell Sci 108:2221-2230; 1995.
14. Frost, H. M. Tetracycline-based histological analysis of bone remodeling. Calcif Tissue Int 3:211-237; 1969.
15. Heath, J. K., Atkinson, S. J., Meikle, M. C., and Reynolds, J. J. Mouse osteoblasts synthesize collagenase in response to bone-resorbing agents. Biochim Biophys Acta 802:151-154; 1984.
16. Hembry, R. M., Bagga, M. R., Reynolds, J. J., and Hamblen, D. L. Immunolocalization studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis. Ann Rheum Dis 54:25-32; 1995.
17. Hembry, R. M., Murphy, G., Cawston, T. E., Dingle, J. T., and Reynolds, J. J. Characterization of a specific antiserum for mammalian collagenase from several species: Immunolocalization of collagenase in rabbit chondrocytes and uterus. J Cell Sci 81:105-123; 1986.
18. Hill, P. A., Murphy, G. M., Docherty, A. J. P., Hembry, R. M., Millican, T. A., and Reynolds, J. J. The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. J Cell Sci 107:3055-3064; 1994.
19. Hoyland, J., Freemont, A., and Sharpe, P. Interleukin-6, IL-6 receptor and IL-6 nuclear factor gene expression in Paget's disease. J Bone Miner Res 9:75-80; 1994.
20. Jayasinghe, J. A. P., Jones, S. J., and Boyde, A. Scanning electron microscopy of human lumbar vertebral trabecular bone surfaces. Virchows Archiv A Pathol Anat 422:25-34; 1993.
21. Meikle, M. C., Bord, S., Hembry, R. M., Compston, J. E., Croucher, P. I., and Reynolds, J. J. Human osteoblasts in culture synthesize collagenase and other matrix metalloproteinases in response to osteotrophic hormones and cytokines. J Cell Sci 103:1093-1099; 1992.
22. Meikle, M. C., McGarrity, A. M., Thomson, B. M., and Reynolds, J. J. Bonederived growth factors modulate collagenase and TIMP (tissue inhibitor of metalloproteinases) activity and type 1 collagen degradation by mouse calvarial osteoblasts. Bone Miner 12:41-55; 1991.
23. Murphy, G., Allan, J. A., Willenbrock, F., Cockett, M. I., O'Connell, J. P., and Docherty, A. J. P. The role of the C-terminal domain in collagenase and stromelysin specificity. J Biol Chem 267:9612-9618; 1992.
24. Murphy, G., Cockett, M. I., Stephens, P. E., Smith, B. J., and Docherty, A. J. P. Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes. Biochem J 248:265-268; 1987.
25. Murphy, G., Cockett, M. I., Ward, R. V., and Docherty, A. J. P. Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDA and 72 kDA gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP). Biochem J 277:277-279; 1991.
26. Murphy, G., Willenbrock, F., Ward, R. V., Cockett, M. I., Eaton, D., and Docherty, A. J. P. The C-terminal domain of 72 kDA gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases. Biochem J 283:637-641; 1992.
27. O'Connell, J. P., Willenbrock, F., Docherty, A. J. P., Eaton, D., and Murphy, G. Analysis of the role of the COOH- terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B. J Biol Chem 269:14967-14973; 1994.
28. Okamura, T., Shimokawa, H., Takagi, Y., Ono, H., and Sasaki, S. Detection of collagenase messenger RNA in odontoclasts of bovine root-resorbing tissue by in situ hybridization. Calcif Tissue Int 52:325-330; 1993.
29. Raina, V. Normal osteoid tissue. J Clin Pathol 25:229-232; 1972.
30. Sakamoto, S. and Sakamoto, M. Bone collagenase, osteoblasts, and cell mediated bone resorption. In: Peck, W. A., Ed. Bone and Mineral Research. Vol. 4. Elsevier: Amsterdam; 1986; 49-102.
31. Tezuka, K., Nemoto, K., Tezuka, Y., Sato, T., Ikeda, Y., Kobori, M., Kawashima, H., Eguhi, H., Hakeda, Y., and Kumegawa, M. Identification of matrix metalloproteinase 9 in rabbit osteoclasts. J Biol Chem 269:15006-15009; 1994.
32. Whitham, S. E., Murphy, G., Angel, P., Rahmsdorf, H. J., Smith, B. J., Lyons, A., Harris, T. J. R., Reynolds, J. J., Herrlich, P., and Docherty, A. J. P. Comparison of human Stromelysin and collagenase by cloning and sequence analysis. Biochem J 240:913-916; 1986.