Drug resistance to ganciclovir observed in suicide gene therapy is due to the loss of integrated herpes simplex virus-thymidine kinase gene

International Journal of Oncology

Volumn 10, Issue 4, 1997, Pages 775-778

  Kimura, Masaki ^a,b   Tagawa, Masatoshi ^a   Takenaga, Keizo ^b   Nakagawara, Akira ^b   Horitsu, Keisuke ^c   Yamaguchi, Taketo ^a   Saisho, Hiromitsu ^a   Sakiyama, Shigeru ^b  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA CANCER CENTER   (Japan)

^c TOKYO KASEI UNIVERSITY   (Japan)

Author keywords

Drug resistance; Ganciclovir; Gene therapy; Herpes simplex virus thymidine kinase gene

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; GENE THERAPY; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; TUMOR XENOGRAFT;

EID: 0030986111     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.4.775     Document Type: Article

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