Intron distribution in ancient paralogs supports random insertion and not random loss

Journal of Molecular Evolution

Volumn 44, Issue 6, 1997, Pages 573-584

  Cho, Glen ^a   Doolittle, Russell F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ancient paralogs; Intron distribution; Random insertion; Random loss

Indexed keywords

ALCOHOL DEHYDROGENASE; AMINOTRANSFERASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ARTICLE; CALCULATION; DATA ANALYSIS; GENE INSERTION; GENE LOSS; HUMAN; INTRON; MATHEMATICAL ANALYSIS; NONHUMAN; PROTEIN FAMILY; SPECIES DIFFERENCE; SPLICEOSOME;

ANIMALS; EVOLUTION, MOLECULAR; HUMANS; INTRONS; PROTEINS;

EID: 0030985059     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00006180     Document Type: Article

References (29)

1. Cavalier-Smith T (1985) Selfish DNA and the origin of introns. Nature 315:283-284
2. Cavalier-Smith T (1991) Intron phylogeny: a new hypothesis. Top Genet 7:145-148
3. Cornish-Bowden A (1985) Are introns structural elements or evolutionary debris? Nature 313:434-435
4. Dayhoff MO (1978) Atlas of protein sequence and structure, vol 5, suppl 3. National Biomedical Research Foundation, Washington, DC
5. Dihb NJ, Newman AJ (1989) Evidence that introns arose at protosplice sites. EMBO J 8:2015-2021
6. Dietmaier W, Fabry S (1994) Analysis of the introns in genes encoding small G proteins. Curr Genet 26:497-505
7. Doonan S, Martini F, Angelaccio S, Pascarella S, Barra D, Bossa F (1986) The complete amino acid sequences of cytosolic and mitochondrial aspartate aminotransferases from horse heart, and inferences on evolution of the isoenzymes. J Mol Evol 23:328-335
8. Dorit LR, Schoenbach L, Gilbert W (1990) How big is the universe of exons? Science 250:1377-1382
9. Feng DF, Doolittle RF (1996) Progressive alignment of amino acid sequences and construction of phylogenetic trees from them. Methods Enzymol 266:368-382
10. Gilbert W (1978) Why genes in pieces? Nature 271:501
11. Gilbert W (1987) The exon theory of genes. Cold Spring Harb Symp Quant Biol 52:901-905
12. Gilbert W, Glynias M (1993) On the ancient nature of introns. Gene 135:137-144
13. Gogarten JP, Kibak H, Dittrich P, Taiz L, Bowman BJ, Manolsen MF, Poole RJ, Date T, Oshima T, et al. (1989) Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes. Proc Natl Acad Sci USA 86:6661-6665
14. Henikoff S, Henikoff JG (1992) Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci USA 89:10915-10919
15. Iwabe N, Kuma K, Hasegawa M, Osawa S, Miyata T (1989) Evolutionary relationships of archaebacteria, eubacteria and eukaryotes inferred from phylogenetic trees of duplicated genes. Proc Natl Acad Sci USA 86:9355-9359
16. Iwabe N, Kuma K, Kishino H, Hawegawa M, Miyata T (1990) Compartmentalized isozyme genes and the origin of introns. J Mol Evol 31:205-210
17. Jellie AM, Tate WP, Trotman CNA (1996) Evolutionary history of introns in a multidomain globin gene. J Mol Evol 42:641-647
18. Kersenach R, Brinkmann H, Liaud M, Zhang D, Martin W, Cerff R (1994) Five identical intron positions in ancient duplicated genes of eubacterial origin. Nature 367:387-389
19. Kwiatowski J, Krawczyk M, Kornacki M, Bailey K, Ayala FJ (1995) Evidence against the exon theory of genes derived from the triose phosphate isomerase gene. Proc Natl Acad Sci USA 92:8503-8506
20. Logsdon JM, Palmer JD, Stoltzfus A, Cerff R, Martin W, Brinkmann H (1994) Origin of introns - early or late? Nature 369:526-528
21. Logsdon JM, Tyshenko MG, Dixon C, Jafari JD, Walker V, Palmer JD (1995) Seven newly discovered intron positions in the triosephosphate isomerase gene: evidence for the introns-late theory. Proc Natl Acad Sci USA 92:8207-8511
22. Palmer JD, Logsdon JM (1991) The recent origins of introns. Curr Opin Genet Dev 1:470-477
23. Rogers JH (1986) Introns between protein domains: selective insertion or frameshifting? Trends Genet 2:223
24. Rogers JH (1989) How were introns inserted into nuclear genes? Trends Genet 5:213-216
25. Smith MW (1988) Structure of vertebrate genes: a statistical analysis implicating selection. J Mol Evol 27:45-55
26. Spiegel MR (1975) Theorems and problems of probability and statistics in Schaum's Outline Series. McGraw Hill, New York
27. Stoltzfus A, Doolittle WF (1993) Slippery introns and globin gene evolution. Curr Biol 3:215-217
28. Stoltzfus A, Spencer DF, Zuker M, Logsdon J, Doolittle WF (1994) Testing the exon theory of genes: the evidence from protein structure. Science 265:202-207
29. Weber K, Kabsch W (1994) Intron positions in actin genes seem unrelated to the secondary structure of the protein. EMBO J 13:1280-1296