메뉴 건너뛰기




Volumn 20, Issue 3, 1996, Pages 475-488

A newly identified gene cluster in Aspergillus nidulans comprises five novel genes localized in the alc region that are controlled both by the specific transactivator AlcR and the general carbon-catabolite repressor CreA

Author keywords

[No Author keywords available]

Indexed keywords

ALCA; ASPERGILLUS; EMERICELLA NIDULANS;

EID: 0029974525     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1996.5301061.x     Document Type: Article
Times cited : (48)

References (44)
  • 1
    • 0016610993 scopus 로고
    • A gene cluster in Aspergillus nidulans with an internally located cis-acting regulatory region
    • Arst, Jr, H.N., and MacDonald, W. (1975) A gene cluster in Aspergillus nidulans with an internally located cis-acting regulatory region. Nature 254: 26-31.
    • (1975) Nature , vol.254 , pp. 26-31
    • Arst Jr., H.N.1    MacDonald, W.2
  • 2
    • 0025354346 scopus 로고
    • An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression
    • Arst, Jr, H.N., Tollervey, D., Dowzer, C.E.A., and Kelly, J.M. (1990) An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression. Mol Microbiol 4: 851-854.
    • (1990) Mol Microbiol , vol.4 , pp. 851-854
    • Arst Jr., H.N.1    Tollervey, D.2    Dowzer, C.E.A.3    Kelly, J.M.4
  • 3
    • 0016606396 scopus 로고
    • Carbon catabolite repression in Aspergillus nidulans
    • Bailey, C., and Arst, Jr, H.N. (1975) Carbon catabolite repression in Aspergillus nidulans. Eur J Biochem 51: 573-577.
    • (1975) Eur J Biochem , vol.51 , pp. 573-577
    • Bailey, C.1    Arst Jr., H.N.2
  • 4
    • 0018613884 scopus 로고
    • Isolation and characterization of further cis- and trans-acting regulatory elements involved in the synthesis of glucose-repressible alcohol dehydrogenase (ADHIII)
    • Ciriacy, M. (1979) Isolation and characterization of further cis- and trans-acting regulatory elements involved in the synthesis of glucose-repressible alcohol dehydrogenase (ADHIII). Mol Gen Genet 176: 427-431.
    • (1979) Mol Gen Genet , vol.176 , pp. 427-431
    • Ciriacy, M.1
  • 5
    • 0014011862 scopus 로고
    • The induction and repression of nitrate reductase in the fungus Aspergillus nidulans
    • Cove, D.J. (1966) The induction and repression of nitrate reductase in the fungus Aspergillus nidulans. Biochim Biophys Acta 113: 51-56.
    • (1966) Biochim Biophys Acta , vol.113 , pp. 51-56
    • Cove, D.J.1
  • 6
    • 0018502444 scopus 로고
    • Genetic studies of nitrate assimilation in Aspergillus nidulans
    • Cove, D.J. (1979) Genetic studies of nitrate assimilation in Aspergillus nidulans. Biol Rev 54: 291-327.
    • (1979) Biol Rev , vol.54 , pp. 291-327
    • Cove, D.J.1
  • 7
    • 0028140060 scopus 로고
    • Two different, adjacent and divergent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans
    • Cubero, B., and Scazzocchio, C. (1994) Two different, adjacent and divergent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans. EMBO J 13: 405-415.
    • (1994) EMBO J , vol.13 , pp. 405-415
    • Cubero, B.1    Scazzocchio, C.2
  • 8
    • 0021915190 scopus 로고
    • Genomic clones of Aspergillus nidulans containing alcA, the structural gene for alcohol dehydrogenase and alcR, a regulatory gene for ethanol metabolism
    • Doy, C.H., Pateman, J.A., Olsen, J.E., Kane, H.J., and Creaser, E.H. (1985) Genomic clones of Aspergillus nidulans containing alcA, the structural gene for alcohol dehydrogenase and alcR, a regulatory gene for ethanol metabolism. DNA 4: 105-114.
    • (1985) DNA , vol.4 , pp. 105-114
    • Doy, C.H.1    Pateman, J.A.2    Olsen, J.E.3    Kane, H.J.4    Creaser, E.H.5
  • 9
    • 0025944347 scopus 로고
    • Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans
    • Dowzer, C.E.A., and Kelly, J.M. (1991) Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans. Mol Cell Biol 11: 5701-5709.
    • (1991) Mol Cell Biol , vol.11 , pp. 5701-5709
    • Dowzer, C.E.A.1    Kelly, J.M.2
  • 10
    • 0026026830 scopus 로고
    • The ethanol utilization regulon of Aspergillus nidulans: The alcA-alcR system as a tool for the expression of recombinant proteins
    • Felenbok, B. (1991) The ethanol utilization regulon of Aspergillus nidulans: the alcA-alcR system as a tool for the expression of recombinant proteins. J Biotechnol 17: 11-18.
    • (1991) J Biotechnol , vol.17 , pp. 11-18
    • Felenbok, B.1
  • 11
    • 0002630611 scopus 로고    scopus 로고
    • Regulation of carbon metabolism in mycelial fungi
    • Brambl, R., and Marzluf, G. (eds). Chapter 17. Berlin: Springer-Verlag
    • Felenbok, B., and Kelly, J.M. (1996) Regulation of carbon metabolism in mycelial fungi. In The Mycota III; Biochemistry and Molecular Biology. Brambl, R., and Marzluf, G. (eds). Chapter 17. Berlin: Springer-Verlag, pp. 369-380.
    • (1996) The Mycota III; Biochemistry and Molecular Biology , pp. 369-380
    • Felenbok, B.1    Kelly, J.M.2
  • 12
    • 0028315108 scopus 로고
    • Alcohol metabolism
    • Progress in Industrial Microbiology. Martinelli, S., and Kinghorn, J.R. (eds). Amsterdam: Elsevier
    • Felenbok, B., and Sealy-Lewis, H.M. (1994) Alcohol metabolism. In Genetics and Physiology of Aspergillus nidulans. Vol. 29, Progress in Industrial Microbiology. Martinelli, S., and Kinghorn, J.R. (eds). Amsterdam: Elsevier, pp. 141-179.
    • (1994) Genetics and Physiology of Aspergillus Nidulans , vol.29 , pp. 141-179
    • Felenbok, B.1    Sealy-Lewis, H.M.2
  • 13
    • 0024232197 scopus 로고
    • The ethanol regulon in Aspergillus nidulans: Characterization and sequence of the positive regulatory gene alcR
    • Felenbok, B., Sequeval, D., Mathieu, M., Sibley, S., Gwynne, D.I., and Davies, R.W. (1988) The ethanol regulon in Aspergillus nidulans: characterization and sequence of the positive regulatory gene alcR. Gene 73: 385-396.
    • (1988) Gene , vol.73 , pp. 385-396
    • Felenbok, B.1    Sequeval, D.2    Mathieu, M.3    Sibley, S.4    Gwynne, D.I.5    Davies, R.W.6
  • 14
    • 0023796802 scopus 로고
    • Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a y-actin
    • Fidel, S., Doonan, J.H., and Morris, N.R. (1988) Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a y-actin. Gene 70: 283-293.
    • (1988) Gene , vol.70 , pp. 283-293
    • Fidel, S.1    Doonan, J.H.2    Morris, N.R.3
  • 15
    • 0029121414 scopus 로고
    • The basal level of transcription of the alc genes in the ethanol regulon in Aspergillus nidulans is controlled both by the specific transactivator AlcR and the general carbon catabolite repressor CreA
    • Fillinger, S., Panozzo, C., Mathieu, M., and Felenbok B. (1995) The basal level of transcription of the alc genes in the ethanol regulon in Aspergillus nidulans is controlled both by the specific transactivator AlcR and the general carbon catabolite repressor CreA. FEBS Lett 368: 547-550.
    • (1995) FEBS Lett , vol.368 , pp. 547-550
    • Fillinger, S.1    Panozzo, C.2    Mathieu, M.3    Felenbok, B.4
  • 16
    • 0023189082 scopus 로고
    • Comparison of the cis acting control regions of two coordinately controlled genes involved in ethanol utilization in Aspergillus nidulans
    • Gwynne, D.I., Buxton, F.P., Sibley, S., Davies, R.W., Lockington, R.A., Scazzocchio, C., and Sealy-Lewis, H.N. (1987) Comparison of the cis acting control regions of two coordinately controlled genes involved in ethanol utilization in Aspergillus nidulans. Gene 51: 205-216.
    • (1987) Gene , vol.51 , pp. 205-216
    • Gwynne, D.I.1    Buxton, F.P.2    Sibley, S.3    Davies, R.W.4    Lockington, R.A.5    Scazzocchio, C.6    Sealy-Lewis, H.N.7
  • 17
    • 0025760720 scopus 로고
    • Heterologous expression and regulation of the Neurospora crassa nit 4 pathway-specific regulatory gene for nitrate assimilation in Aspergillus nidulans
    • Hawker, K.L., Montague, P., Marzluf, G.A., and Kinghorn, J.R. (1991) Heterologous expression and regulation of the Neurospora crassa nit 4 pathway-specific regulatory gene for nitrate assimilation in Aspergillus nidulans. Gene 100: 237-240.
    • (1991) Gene , vol.100 , pp. 237-240
    • Hawker, K.L.1    Montague, P.2    Marzluf, G.A.3    Kinghorn, J.R.4
  • 18
    • 0011216698 scopus 로고
    • Gene roles in the prn gene cluster of Aspergillus nidulans
    • Jones, S.A., Arst, Jr, H.N., and MacDonald, W. (1981) Gene roles in the prn gene cluster of Aspergillus nidulans. Curr Genet 3: 49-56.
    • (1981) Curr Genet , vol.3 , pp. 49-56
    • Jones, S.A.1    Arst Jr., H.N.2    MacDonald, W.3
  • 19
    • 0021735650 scopus 로고
    • Primary structure of the nuclear PUT2 gene involved in the mitochondrial pathway for proline utilization in Saccharomyces cerevisiae
    • Krywicki, K.A., and Brandiss, C. (1984) Primary structure of the nuclear PUT2 gene involved in the mitochondrial pathway for proline utilization in Saccharomyces cerevisiae. Mol Cell Biol 4: 2837-2842.
    • (1984) Mol Cell Biol , vol.4 , pp. 2837-2842
    • Krywicki, K.A.1    Brandiss, C.2
  • 20
    • 0026061154 scopus 로고
    • Correct intron splicing generates a new type of a putative Zn-binding domain in a transcriptional activator of Aspergillus nidulans
    • Kulmburg, P., Prangé, T, Mathieu, M., Sequeval, D., Scazzocchio, C., and Felenbok, B. (1991) Correct intron splicing generates a new type of a putative Zn-binding domain in a transcriptional activator of Aspergillus nidulans. FEBS Lett 280: 11-16.
    • (1991) FEBS Lett , vol.280 , pp. 11-16
    • Kulmburg, P.1    Prangé, T.2    Mathieu, M.3    Sequeval, D.4    Scazzocchio, C.5    Felenbok, B.6
  • 21
    • 0026693313 scopus 로고
    • Identification of the promoter region involved in the autoregulation of the transcriptional activator ALCR in Aspergillus nidulans
    • Kulmburg, P., Sequeval, D., Lenouvel, F., Mathieu, M., and Felenbok, B. (1992a) Identification of the promoter region involved in the autoregulation of the transcriptional activator ALCR in Aspergillus nidulans. Mol Cell Biol 12: 1932-1939.
    • (1992) Mol Cell Biol , vol.12 , pp. 1932-1939
    • Kulmburg, P.1    Sequeval, D.2    Lenouvel, F.3    Mathieu, M.4    Felenbok, B.5
  • 22
    • 0026657596 scopus 로고
    • Specific binding sites for the activator protein, ALCR, in the alcA promoter of the ethanol regulon of Aspergillus nidulans
    • Kulmburg, P., Judewicz, N., Mathieu, M., Sequeval, D., and Felenbok, B. (1992b) Specific binding sites for the activator protein, ALCR, in the alcA promoter of the ethanol regulon of Aspergillus nidulans. J Biol Chem 267: 21146-21153.
    • (1992) J Biol Chem , vol.267 , pp. 21146-21153
    • Kulmburg, P.1    Judewicz, N.2    Mathieu, M.3    Sequeval, D.4    Felenbok, B.5
  • 23
    • 0027481684 scopus 로고
    • Specific binding sites in the alcR and alcA promoters of the ethanol regulon for the CREA repressor mediating carbon catabolite repression in Aspergillus nidulans
    • Kulmburg, P., Mathieu, M., Dowzer, C., Kelly, J., and Felenbok, B. (1993) Specific binding sites in the alcR and alcA promoters of the ethanol regulon for the CREA repressor mediating carbon catabolite repression in Aspergillus nidulans. Mol Microbiol 7: 847-857.
    • (1993) Mol Microbiol , vol.7 , pp. 847-857
    • Kulmburg, P.1    Mathieu, M.2    Dowzer, C.3    Kelly, J.4    Felenbok, B.5
  • 25
    • 0023445125 scopus 로고
    • Regulation of alcR, the positive regulatory gene of the ethanol utilization regulon of Aspergillus nidulans
    • Lockington, R., Scazzocchio, C., Sequeval, D., Mathieu, M., and Felenbok, B. (1987) Regulation of alcR, the positive regulatory gene of the ethanol utilization regulon of Aspergillus nidulans. Mol Microbiol 1: 275-281.
    • (1987) Mol Microbiol , vol.1 , pp. 275-281
    • Lockington, R.1    Scazzocchio, C.2    Sequeval, D.3    Mathieu, M.4    Felenbok, B.5
  • 26
    • 0021916247 scopus 로고
    • Cloning and characterization of the ethanol utilization in Aspergillus nidulans
    • Lockington, R.A., Sealy-Lewis, H.N., Scazzocchio, C., and Davies, R.W. (1985) Cloning and characterization of the ethanol utilization in Aspergillus nidulans. Gene 33: 137-149.
    • (1985) Gene , vol.33 , pp. 137-149
    • Lockington, R.A.1    Sealy-Lewis, H.N.2    Scazzocchio, C.3    Davies, R.W.4
  • 27
    • 0022447099 scopus 로고
    • Transcription initiation of the Saccharomyces cerevisiae iso-1-cytochrome c gene. Multiple, independent T-A-T-A sequences
    • McNeil, J.B., and Smith, M. (1986) Transcription initiation of the Saccharomyces cerevisiae iso-1-cytochrome c gene. Multiple, independent T-A-T-A sequences. J Mol Biol 187: 363-378.
    • (1986) J Mol Biol , vol.187 , pp. 363-378
    • McNeil, J.B.1    Smith, M.2
  • 28
    • 0028094620 scopus 로고
    • The Aspergillus nidulans CREA protein mediates glucose repression of the ethanol regulon at various levels through competition with the ALCR-specific transactivator
    • Mathieu, M., and Felenbok, B. (1994) The Aspergillus nidulans CREA protein mediates glucose repression of the ethanol regulon at various levels through competition with the ALCR-specific transactivator. EMBO J 13: 4022-4027.
    • (1994) EMBO J , vol.13 , pp. 4022-4027
    • Mathieu, M.1    Felenbok, B.2
  • 29
    • 0023626107 scopus 로고
    • Cloning, mapping and molecular analysis of the pyrG (orotidine-5′-phosphate decarboxylase) gene of Aspergillus nidulans
    • Oakley, B.R., Rinehart, J.E., Mitchell, B.L., Oakley, C.E., Carmona, C., Gray, G.L., and May, G.S. (1987) Cloning, mapping and molecular analysis of the pyrG (orotidine-5′-phosphate decarboxylase) gene of Aspergillus nidulans. Gene 61: 385-399.
    • (1987) Gene , vol.61 , pp. 385-399
    • Oakley, B.R.1    Rinehart, J.E.2    Mitchell, B.L.3    Oakley, C.E.4    Carmona, C.5    Gray, G.L.6    May, G.S.7
  • 31
    • 0020682046 scopus 로고
    • Regulation of alcohol dehydrogenase and aldehyde dehydrogenase in Aspergillus nidulans
    • Pateman, J.A., Doy, C.H., Olsen, J.E., Norris, U., Creaser, E.H., Hynes, M.J. (1983) Regulation of alcohol dehydrogenase and aldehyde dehydrogenase in Aspergillus nidulans. Proc R Soc Lond B 217: 243-264.
    • (1983) Proc R Soc Lond B , vol.217 , pp. 243-264
    • Pateman, J.A.1    Doy, C.H.2    Olsen, J.E.3    Norris, U.4    Creaser, E.H.5    Hynes, M.J.6
  • 32
    • 0025188859 scopus 로고
    • Sequences of the isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes
    • Peñalva, M.A., Moya, A., Dopazo, J., and Ramòn, D. (1990) Sequences of the isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes. Proc R Soc Lond B 241: 164-169.
    • (1990) Proc R Soc Lond B , vol.241 , pp. 164-169
    • Peñalva, M.A.1    Moya, A.2    Dopazo, J.3    Ramòn, D.4
  • 34
    • 0023777869 scopus 로고
    • Isolation and characterisation of the glyceraldehyde-3-phosphate dehydrogenase gene of Aspergillus nidulans
    • Punt, P.J., Dingemanse, M.A., Jacobs-Meijsing, B.J.M., Pouwels, P.H., and van den Hondel, C.A.M.J.J. (1988) Isolation and characterisation of the glyceraldehyde-3-phosphate dehydrogenase gene of Aspergillus nidulans. Gene 69: 49-57.
    • (1988) Gene , vol.69 , pp. 49-57
    • Punt, P.J.1    Dingemanse, M.A.2    Jacobs-Meijsing, B.J.M.3    Pouwels, P.H.4    Van Den Hondel, C.A.M.J.J.5
  • 35
    • 0029143645 scopus 로고
    • The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NIrA binding sites which act bi-directionally
    • Punt, P.J., Strauss, J., Smit, R., Kinghorn, J.R., van den Hondel, C.A.M.J.J., and Scazzocchio, C. (1995) The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NIrA binding sites which act bi-directionally. Mol Cell Biol 15: 5688-5699.
    • (1995) Mol Cell Biol , vol.15 , pp. 5688-5699
    • Punt, P.J.1    Strauss, J.2    Smit, R.3    Kinghorn, J.R.4    Van Den Hondel, C.A.M.J.J.5    Scazzocchio, C.6
  • 36
    • 0023514264 scopus 로고
    • Cloning and characterization of the isopenicillin N synthase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans
    • Ramon, D., Carramolino, L., Patino, C., Sanchez, F., and Peñalva, M.A. (1987) Cloning and characterization of the isopenicillin N synthase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans. Gene 57: 171-181.
    • (1987) Gene , vol.57 , pp. 171-181
    • Ramon, D.1    Carramolino, L.2    Patino, C.3    Sanchez, F.4    Peñalva, M.A.5
  • 37
    • 0018579722 scopus 로고
    • Allele specific, gene unspecific, suppressors in Aspergillus nidulans
    • Roberts, T.J., Martinelli, S., Scazzocchio, C. (1979) Allele specific, gene unspecific, suppressors in Aspergillus nidulans. Mol Gen Genet 177: 57-64.
    • (1979) Mol Gen Genet , vol.177 , pp. 57-64
    • Roberts, T.J.1    Martinelli, S.2    Scazzocchio, C.3
  • 39
    • 0017681196 scopus 로고
    • DNA sequencing with chain-terminating inhibitors
    • Sanger, F., Nickels, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 5463-5467
    • Sanger, F.1    Nickels, S.2    Coulson, A.R.3
  • 40
    • 0028319710 scopus 로고
    • The proline utilisation pathway, history and beyond
    • Martinelli, S., and Kinghorn, J.R. (eds). Amsterdam: Elsevier Progress in Industrial Microbiology
    • Scazzocchio, C. (1994) The proline utilisation pathway, history and beyond. In Aspergillus: 50 Years On. Martinelli, S., and Kinghorn, J.R. (eds). Amsterdam: Elsevier, Vol. 29, Progress in Industrial Microbiology, pp. 259-277.
    • (1994) Aspergillus: 50 Years on , vol.29 , pp. 259-277
    • Scazzocchio, C.1
  • 43
    • 0019176377 scopus 로고
    • The isolation and characterisation of mutants defective in nitrate assimilation in Neurospora crassa
    • Tomsett, B.A., and Garret, R.H. (1980) The isolation and characterisation of mutants defective in nitrate assimilation in Neurospora crassa. Genetics 95: 649-660.
    • (1980) Genetics , vol.95 , pp. 649-660
    • Tomsett, B.A.1    Garret, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.