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Volumn 28, Issue 1, 1997, Pages 21-31

Strong c-Jun/AP-1 immunoreactivity is restricted to apoptotic cells following intracerebral ibotenic acid injection in developing rats

Author keywords

Apoptosis; c Jun; c Jun N terminal kinase 1; Cell death; Developing brain

Indexed keywords

ANTIBODY; IBOTENIC ACID; ONCOPROTEIN; PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 0030983123     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(97)01176-0     Document Type: Article
Times cited : (19)

References (60)
  • 1
    • 0025077481 scopus 로고
    • Redox regulation of fos and jun DNA binding activity in vitro
    • Abate, C., Lekha, P., Rauscher, F.J. and Curran, T. (1990) Redox regulation of fos and jun DNA binding activity in vitro. Science, 249: 1157-1160.
    • (1990) Science , vol.249 , pp. 1157-1160
    • Abate, C.1    Lekha, P.2    Rauscher, F.J.3    Curran, T.4
  • 2
    • 0029977363 scopus 로고    scopus 로고
    • Thalamic and basal forebrain afferents modulate the development of parvalbumin and calbindin D28k immunoreactivity in the barrel cortex of the rat
    • Alcántara, S., Soriano, E. and Ferrer, I. (1996) Thalamic and basal forebrain afferents modulate the development of parvalbumin and calbindin D28k immunoreactivity in the barrel cortex of the rat. Eur. J. Neurosci., 8: 1522-1534.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1522-1534
    • Alcántara, S.1    Soriano, E.2    Ferrer, I.3
  • 3
    • 0024276523 scopus 로고
    • The jun proto-oncogene is positively autoregulated by its product jun/ AP-1
    • Angel, P., Hattori, K., Smeal, T. and Karin, M. (1988) The jun proto-oncogene is positively autoregulated by its product jun/ AP-1. Cell, 5: 875-885.
    • (1988) Cell , vol.5 , pp. 875-885
    • Angel, P.1    Hattori, K.2    Smeal, T.3    Karin, M.4
  • 4
    • 0028941909 scopus 로고
    • Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: Evidence of apoptosis during selective neuronal loss
    • Beilharz, E.J., Williams, C.E., Dragunow, M., Sirimane, E.S. and Gluckman, P.D. (1995) Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence of apoptosis during selective neuronal loss. Mol. Brain Res., 29: 1-14.
    • (1995) Mol. Brain Res. , vol.29 , pp. 1-14
    • Beilharz, E.J.1    Williams, C.E.2    Dragunow, M.3    Sirimane, E.S.4    Gluckman, P.D.5
  • 5
    • 0025806587 scopus 로고
    • Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
    • Binetruy, B., Smeal, T. and Karin, M. (1991) Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature, 351: 122-127.
    • (1991) Nature , vol.351 , pp. 122-127
    • Binetruy, B.1    Smeal, T.2    Karin, M.3
  • 6
    • 0025096470 scopus 로고
    • Transcription factor phosphorylation: A link between signal transduction and the regulation of gene expression
    • Bohmann, D. (1990) Transcription factor phosphorylation: a link between signal transduction and the regulation of gene expression. Cancer Cells, 2: 337-343.
    • (1990) Cancer Cells , vol.2 , pp. 337-343
    • Bohmann, D.1
  • 7
    • 0026029808 scopus 로고
    • Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
    • Boyle, W.J., Smeal, T., Defize, L.H., Angel, P., Woodgett, J.R., Karin, M. and Hunter, T. (1991) Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell, 64: 573-584.
    • (1991) Cell , vol.64 , pp. 573-584
    • Boyle, W.J.1    Smeal, T.2    Defize, L.H.3    Angel, P.4    Woodgett, J.R.5    Karin, M.6    Hunter, T.7
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-dye binding
    • Bradford, M.A. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-dye binding. Anal. Biochem., 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.A.1
  • 9
    • 0024815627 scopus 로고
    • Jun-B differs in its biological properties from and is a negative regulator of c-Jun
    • Chiu, R., Angel, P. and Karin, M. (1989) Jun-B differs in its biological properties from and is a negative regulator of c-Jun. Cell, 59: 979-986.
    • (1989) Cell , vol.59 , pp. 979-986
    • Chiu, R.1    Angel, P.2    Karin, M.3
  • 10
    • 0000634050 scopus 로고
    • The use of excitatory amino acids as selective neurotoxins
    • Methods in Chemical Neuronatomy, Elsevier/North Holland, Amsterdam
    • Coyle, J.T. and Schwarcz, R. (1983) The use of excitatory amino acids as selective neurotoxins. In: Handbook of Chemical Neuroanatomy, Vol. 1, Methods in Chemical Neuronatomy, Elsevier/North Holland, Amsterdam, pp. 508-527.
    • (1983) Handbook of Chemical Neuroanatomy , vol.1 , pp. 508-527
    • Coyle, J.T.1    Schwarcz, R.2
  • 11
    • 0027173483 scopus 로고
    • Jun B differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers
    • Deng, T. and Karin, M. (1993) Jun B differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev., 7: 479-490.
    • (1993) Genes Dev. , vol.7 , pp. 479-490
    • Deng, T.1    Karin, M.2
  • 12
    • 0028329953 scopus 로고
    • JNK-1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I-H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R.J. (1994) JNK-1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell, 76: 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 13
    • 0028356223 scopus 로고
    • Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischemic injury to the young rat brain
    • Dragunow, M., Beilharz, E., Sirimane, E., Lawlor, P., Williams, C., Bravo, R. and Gluckman, P. (1994) Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischemic injury to the young rat brain. Mol. Brain Res., 25: 19-33.
    • (1994) Mol. Brain Res. , vol.25 , pp. 19-33
    • Dragunow, M.1    Beilharz, E.2    Sirimane, E.3    Lawlor, P.4    Williams, C.5    Bravo, R.6    Gluckman, P.7
  • 14
    • 0028866102 scopus 로고
    • The role of inducible transcription factors in apoptotic cell death
    • Dragunow, M. and Preston, K. (1995) The role of inducible transcription factors in apoptotic cell death. Brain Res. Rev., 21: 1-28.
    • (1995) Brain Res. Rev. , vol.21 , pp. 1-28
    • Dragunow, M.1    Preston, K.2
  • 15
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-Jun as necessary for neuronal apoptosis
    • Estus, S., Zaks, W., Freeman, R.S., Gruda, M., Bravo, R. and Johnson, E.M. (1994) Altered gene expression in neurons during programmed cell death: identification of c-Jun as necessary for neuronal apoptosis. J. Cell Biol., 127: 1717-1727.
    • (1994) J. Cell Biol. , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson, E.M.6
  • 16
    • 0030462575 scopus 로고    scopus 로고
    • Study of mechanisms involved in cell death in the normal developing brain, and following ionizing radiation, methylazoxymethanol, and hypoxia-ischaemia in the rat
    • Ferrer, I. (1996) Study of mechanisms involved in cell death in the normal developing brain, and following ionizing radiation, methylazoxymethanol, and hypoxia-ischaemia in the rat. Neuropathol. Appl. Neurobiol., 22: 489-494.
    • (1996) Neuropathol. Appl. Neurobiol. , vol.22 , pp. 489-494
    • Ferrer, I.1
  • 18
    • 0029992798 scopus 로고    scopus 로고
    • Selective c-Jun overexpression is associated with ionizing radiation-induced apoptosis in the developing cerebellum of the rat
    • Ferrer, I., Olive, M., Blanco, R., Cinos, C. and Planas, A.M. (1996a) Selective c-Jun overexpression is associated with ionizing radiation-induced apoptosis in the developing cerebellum of the rat. Mol. Brain Res., 38: 91100.
    • (1996) Mol. Brain Res. , vol.38 , pp. 91100
    • Ferrer, I.1    Olive, M.2    Blanco, R.3    Cinos, C.4    Planas, A.M.5
  • 19
    • 0029967179 scopus 로고    scopus 로고
    • Naturally occurring (programmed) and radiation induced apoptosis are associated with selective c-Jun expression in the developing rat brain
    • Ferrer, I., Olive, M., Ribera, J. and Planas, A.M. (1996b) Naturally occurring (programmed) and radiation induced apoptosis are associated with selective c-Jun expression in the developing rat brain. Eur. J. Neurosci., 8: 1286-1298.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1286-1298
    • Ferrer, I.1    Olive, M.2    Ribera, J.3    Planas, A.M.4
  • 20
    • 0030635690 scopus 로고    scopus 로고
    • Methyl-azoxy-methanol acetate-induced apoptosis in the external granule cell layer of the developing cerebellum of the rat is associated with strong c-Jun expression and formation of high molecular weight c-Jun
    • Ferrer, I., Pozas, E., Marti, M., Blanco, R. and Planas, A.M. (1997) Methyl-azoxy-methanol acetate-induced apoptosis in the external granule cell layer of the developing cerebellum of the rat is associated with strong c-Jun expression and formation of high molecular weight c-Jun. Neuropathol. Exp. Neurol., 56: 1-9.
    • (1997) Neuropathol. Exp. Neurol. , vol.56 , pp. 1-9
    • Ferrer, I.1    Pozas, E.2    Marti, M.3    Blanco, R.4    Planas, A.M.5
  • 21
    • 0343213132 scopus 로고    scopus 로고
    • Strong c-Jun immunoreactivity is associated with apoptotic cell death in human tumors of the central nervous system
    • Ferrer, I., Segui, J. and Olive, M. (1996 c) Strong c-Jun immunoreactivity is associated with apoptotic cell death in human tumors of the central nervous system. Neurosci. Lett., 213: 1-5.
    • (1996) Neurosci. Lett. , vol.213 , pp. 1-5
    • Ferrer, I.1    Segui, J.2    Olive, M.3
  • 22
    • 0028201739 scopus 로고
    • Evidence of nuclear DNA fragmentation following hypoxia-ischemia in the infant rat brain, and transient forebrain ischemia in the adult gerbil
    • Ferrer, I., Tortosa, A., Macaya, A., Sierra, A., Moreno, D., Munell, F., Blanco, R. and Squier W. (1994) Evidence of nuclear DNA fragmentation following hypoxia-ischemia in the infant rat brain, and transient forebrain ischemia in the adult gerbil. Brain Pathol., 4: 115-122.
    • (1994) Brain Pathol. , vol.4 , pp. 115-122
    • Ferrer, I.1    Tortosa, A.2    Macaya, A.3    Sierra, A.4    Moreno, D.5    Munell, F.6    Blanco, R.7    Squier, W.8
  • 23
    • 0027931560 scopus 로고
    • DNA fragmentation in rat brain after intraperitoneal administration of kainate
    • Filipkowski, R.K., Hetman, M., Kaminska, B. and Kaczmarek L. (1994) DNA fragmentation in rat brain after intraperitoneal administration of kainate. NeuroReport, 5: 1538-1540.
    • (1994) NeuroReport , vol.5 , pp. 1538-1540
    • Filipkowski, R.K.1    Hetman, M.2    Kaminska, B.3    Kaczmarek, L.4
  • 24
    • 0029623172 scopus 로고
    • Neuronal expression of AP-1 proteins in excitotoxic-neurodegenerative disorders and following nerve fiber lesions
    • Gass, P. and Herdegen, T. (1995 Neuronal expression of AP-1 proteins in excitotoxic-neurodegenerative disorders and following nerve fiber lesions. Prog. Neurobiol., 47: 257-290.
    • (1995) Prog. Neurobiol. , vol.47 , pp. 257-290
    • Gass, P.1    Herdegen, T.2
  • 25
    • 0027284098 scopus 로고
    • Spatiotemporal induction of immediate early genes in the rat brain after limbic seizures: Effects of NMDA receptor antagonist MK-801
    • Gass, P., Herdegen, T., Bravo, R. and Kiessling, M. (1993) Spatiotemporal induction of immediate early genes in the rat brain after limbic seizures: Effects of NMDA receptor antagonist MK-801. Eur. J. Neurosci., 5: 933943.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 933943
    • Gass, P.1    Herdegen, T.2    Bravo, R.3    Kiessling, M.4
  • 26
    • 0026784891 scopus 로고
    • Induction of FOS and JUN proteins after focal ischemia in the rat: Differential effect of the N-methyl-D-aspartate receptor antagonist MK-801
    • Gass, P., Spranger, M., Herdegen, T., Bravo, R., Kck, P., Hacke, W. and Kiessling, M. (1992) Induction of FOS and JUN proteins after focal ischemia in the rat: Differential effect of the N-methyl-D-aspartate receptor antagonist MK-801. Acta Neuropathol., 84: 545-553.
    • (1992) Acta Neuropathol. , vol.84 , pp. 545-553
    • Gass, P.1    Spranger, M.2    Herdegen, T.3    Bravo, R.4    Kck, P.5    Hacke, W.6    Kiessling, M.7
  • 27
    • 0029083809 scopus 로고
    • DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration)
    • Guillardon, F., Baurle, J., Grusser-Cornehls, U. and Zimmermann, M. (1995) DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration). NeuroReport, 6: 1766-1768.
    • (1995) NeuroReport , vol.6 , pp. 1766-1768
    • Guillardon, F.1    Baurle, J.2    Grusser-Cornehls, U.3    Zimmermann, M.4
  • 28
    • 0027439911 scopus 로고
    • Differential expression of immediate early genes after transection of the facial nerve
    • Haas, C.A., Donath, C. and Kreutzberg, G.W. (1993) Differential expression of immediate early genes after transection of the facial nerve. Neuroscience, 53: 91-99.
    • (1993) Neuroscience , vol.53 , pp. 91-99
    • Haas, C.A.1    Donath, C.2    Kreutzberg, G.W.3
  • 29
    • 0029012476 scopus 로고
    • A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
    • Ham, J., Babij, C., Whifield, J., Pfarr, C.M., Lallemand D., Yaniv, M. and Rubin, L.L. (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron, 14: 927-939.
    • (1995) Neuron , vol.14 , pp. 927-939
    • Ham, J.1    Babij, C.2    Whifield, J.3    Pfarr, C.M.4    Lallemand, D.5    Yaniv, M.6    Rubin, L.L.7
  • 30
    • 0028556396 scopus 로고
    • Expression of c-Jun and Jun D transcription factors represent specific changes in neuronal gene expression following axotomy
    • Herdegen, T. and Zimmermann, M. (1994) Expression of c-Jun and Jun D transcription factors represent specific changes in neuronal gene expression following axotomy. Prog. Brain Res., 103: 153-171.
    • (1994) Prog. Brain Res. , vol.103 , pp. 153-171
    • Herdegen, T.1    Zimmermann, M.2
  • 31
    • 0027369909 scopus 로고
    • Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain
    • Heron, A., Pollard, H., Dessi, F., Moreau, J., Lasbennes F., Ben-Ari, Y. and Charriaut-Marlangue, C. (1993) Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain. J. Neurochem., 61: 1973-1976.
    • (1993) J. Neurochem. , vol.61 , pp. 1973-1976
    • Heron, A.1    Pollard, H.2    Dessi, F.3    Moreau, J.4    Lasbennes, F.5    Ben-Ari, Y.6    Charriaut-Marlangue, C.7
  • 32
    • 0027423418 scopus 로고
    • Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., Lin, A., Smeal, T., Minden, A. and Karin, M. (1993) Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev., 7: 2135-2148.
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 33
    • 0028933896 scopus 로고
    • DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat
    • Hill, I.E., MacManus, J.P., Rasquinha, I. and Tuor, U.I. (1995) DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. Brain Res., 676: 398-403.
    • (1995) Brain Res. , vol.676 , pp. 398-403
    • Hill, I.E.1    MacManus, J.P.2    Rasquinha, I.3    Tuor, U.I.4
  • 34
    • 0026636883 scopus 로고
    • The regulation of transcription by phosphorylation
    • Hunter, T. and Karin, M. (1992) The regulation of transcription by phosphorylation. Cell, 70: 375-387.
    • (1992) Cell , vol.70 , pp. 375-387
    • Hunter, T.1    Karin, M.2
  • 35
    • 0027469488 scopus 로고
    • Differential expression of immediate early genes in rubrospinal neurons following axotomy in rat
    • Jenkins, R., Telzlaff, W. and Hunt, S.P. (1993a) Differential expression of immediate early genes in rubrospinal neurons following axotomy in rat. Eur. J. Neurosci., 5: 203-209.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 203-209
    • Jenkins, R.1    Telzlaff, W.2    Hunt, S.P.3
  • 36
    • 0027173147 scopus 로고
    • Expression of c-Jun as a response to dorsal root and peripheral nerve section in damaged and adjacent intact primary sensory neurons in the rat
    • Jenkins, R., McMahon, S.B., Bond, A.B. and Hunt, S.P. (1993b) Expression of c-Jun as a response to dorsal root and peripheral nerve section in damaged and adjacent intact primary sensory neurons in the rat. Eur. J. Neurosci., 5: 751-759.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 751-759
    • Jenkins, R.1    McMahon, S.B.2    Bond, A.B.3    Hunt, S.P.4
  • 37
    • 0028322193 scopus 로고
    • Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors
    • Karin, M. (1994) Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr. Opin. Cell Biol., 6: 415-424.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 415-424
    • Karin, M.1
  • 38
    • 0029025008 scopus 로고
    • Kainic acid-induced neuronal death is associated with DNa damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats
    • Kasof, G.M., Mandelzys, A., Maika, S.D., Hammer, R.E., Curran T. and Morgan, J.I. (1995) Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J. Neurosci., 15: 4238-4249.
    • (1995) J. Neurosci. , vol.15 , pp. 4238-4249
    • Kasof, G.M.1    Mandelzys, A.2    Maika, S.D.3    Hammer, R.E.4    Curran, T.5    Morgan, J.I.6
  • 39
    • 0027527125 scopus 로고
    • Immediate early gene expression in experimental epilepsy
    • Kiessling, M. and Gass, P. (1993) Immediate early gene expression in experimental epilepsy. Brain Pathol., 3: 381-393.
    • (1993) Brain Pathol. , vol.3 , pp. 381-393
    • Kiessling, M.1    Gass, P.2
  • 40
    • 0028217064 scopus 로고
    • Stimulus-transcription coupling in focal cerebral ischemia
    • Kiessling, M. and Gass, P. (1994) Stimulus-transcription coupling in focal cerebral ischemia. Brain Pathol., 4: 77-83.
    • (1994) Brain Pathol. , vol.4 , pp. 77-83
    • Kiessling, M.1    Gass, P.2
  • 41
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 42
    • 0027428846 scopus 로고
    • Expression of immediate-early gene proteins following axotomy and inhibition of axonal transport in the rat CNS
    • Leah, J.D., Herdegen, T., Murashov, A., Dragunow, M. and Bravo, R. (1993) Expression of immediate-early gene proteins following axotomy and inhibition of axonal transport in the rat CNS. Neuroscience, 57: 53-66.
    • (1993) Neuroscience , vol.57 , pp. 53-66
    • Leah, J.D.1    Herdegen, T.2    Murashov, A.3    Dragunow, M.4    Bravo, R.5
  • 44
    • 0027501851 scopus 로고
    • Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
    • Linnik, M.D., Zobrist, R.H. and Hatfield, M.D. (1993) Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke, 2: 2002-2009.
    • (1993) Stroke , vol.2 , pp. 2002-2009
    • Linnik, M.D.1    Zobrist, R.H.2    Hatfield, M.D.3
  • 45
    • 0027714833 scopus 로고
    • Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
    • MacManus, J.P., Buchan, A.M., Hill, I.E., Rasquinha, I. and Preston, E. (1993) Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci. Lett., 164: 89-92.
    • (1993) Neurosci. Lett. , vol.164 , pp. 89-92
    • MacManus, J.P.1    Buchan, A.M.2    Hill, I.E.3    Rasquinha, I.4    Preston, E.5
  • 47
    • 0030581101 scopus 로고    scopus 로고
    • Jun expression is found in neurons located in the vicinity of subacute plaques in patients with multiple sclerosis
    • Martin, G., Segui, J., Diaz-Villoslada, P., Montalban, X., Planas, A.M. and Ferrer, I. (1996) Jun expression is found in neurons located in the vicinity of subacute plaques in patients with multiple sclerosis. Neurosci. Lett., 212: 95-98.
    • (1996) Neurosci. Lett. , vol.212 , pp. 95-98
    • Martin, G.1    Segui, J.2    Diaz-Villoslada, P.3    Montalban, X.4    Planas, A.M.5    Ferrer, I.6
  • 48
    • 0025959674 scopus 로고
    • Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun
    • Morgan, J.I. and Curran, T. (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci., 14: 421-451.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 421-451
    • Morgan, J.I.1    Curran, T.2
  • 49
    • 0026766082 scopus 로고
    • Determining the effect of inducible protein phosphorylation on the DNA-binding activity of transcription factors
    • Pavassiliou, A.G., Bohmann, K. and Bohmann, D. (1992) Determining the effect of inducible protein phosphorylation on the DNA-binding activity of transcription factors. Anal. Biochem., 203: 302-309.
    • (1992) Anal. Biochem. , vol.203 , pp. 302-309
    • Pavassiliou, A.G.1    Bohmann, K.2    Bohmann, D.3
  • 50
    • 0027268365 scopus 로고
    • Elevated basal AP-1 DNA binding activity in developing rat brain
    • Pennypacker, K.R., Dreyer, D., Hong, J.S. and McMillian, M.K. (1993) Elevated basal AP-1 DNA binding activity in developing rat brain. Mol. Brain Res., 19: 349-352.
    • (1993) Mol. Brain Res. , vol.19 , pp. 349-352
    • Pennypacker, K.R.1    Dreyer, D.2    Hong, J.S.3    McMillian, M.K.4
  • 52
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
    • Portera-Cailliau, C., Hedreen, J.C., Price, D.L. and Koliatsos, V.E. (1995) Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J. Neurosci., 15: 3775-3787.
    • (1995) J. Neurosci. , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.E.4
  • 53
    • 0031029859 scopus 로고    scopus 로고
    • Excitotoxic neuronal death in the immature brain is a topologically organized apoptosis-necrosis morphological continuum
    • Portera-Cailliau, C., Price, D.L. and Martin, L.J. (1997) Excitotoxic neuronal death in the immature brain is a topologically organized apoptosis-necrosis morphological continuum. J. Comp. Neurol., 378: 70-87.
    • (1997) J. Comp. Neurol. , vol.378 , pp. 70-87
    • Portera-Cailliau, C.1    Price, D.L.2    Martin, L.J.3
  • 56
    • 0028631458 scopus 로고
    • The role of jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal death, and plastic adaptations in vivo
    • Schlingensiepen, K.H., Wollnik, F., Kunst, M. and Schlingensiepen, R. (1994) The role of jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal death, and plastic adaptations in vivo. Cell. Mol. Neurobiol., 14: 487-505.
    • (1994) Cell. Mol. Neurobiol. , vol.14 , pp. 487-505
    • Schlingensiepen, K.H.1    Wollnik, F.2    Kunst, M.3    Schlingensiepen, R.4
  • 57
    • 0024800229 scopus 로고
    • Jun-B inhibits and c-Fos stimulates the transforming and transactivation activities of c-Jun
    • Schütte, J., Viallet, J., Nau, M., Segal, S., Fedorko, J. and Minna, J. (1989) Jun-B inhibits and c-Fos stimulates the transforming and transactivation activities of c-Jun. Cell, 59: 987-997.
    • (1989) Cell , vol.59 , pp. 987-997
    • Schütte, J.1    Viallet, J.2    Nau, M.3    Segal, S.4    Fedorko, J.5    Minna, J.6
  • 58
    • 0025267015 scopus 로고
    • The regulation and function of c-fos and other immediate early genes in the nervous system
    • Sheng, M. and Greenberg, M.E. (1990) The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron, 4: 477-485.
    • (1990) Neuron , vol.4 , pp. 477-485
    • Sheng, M.1    Greenberg, M.E.2
  • 59
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal, T., Binetruy, B., Mercola, D.A., Birrer, M. and Karin, M. (1991) Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature, 354: 494-496.
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 60
    • 0026696344 scopus 로고
    • Oncoprotein mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73
    • Smeal, T., Binetruy, B., Mercola, D., Grover-Bardwick, A., Heidecker, G., Rapp, U.R. and Karin, M. (1992) Oncoprotein mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol. Cell. Biol., 12: 3507-3513.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3507-3513
    • Smeal, T.1    Binetruy, B.2    Mercola, D.3    Grover-Bardwick, A.4    Heidecker, G.5    Rapp, U.R.6    Karin, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.