Parasite genome analysis. Genome research in Trypanosoma brucei: Chromosome size polymorphism and its relevance to genome mapping and analysis

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 91, Issue 2, 1997, Pages 116-120

  Melville, Sara E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Chromosomes; Genome mapping; Karyotype; Trypanosoma brucei; Trypanosomiasis

Indexed keywords

CHROMOSOME NUMBER; CHROMOSOME SIZE; CONFERENCE PAPER; DNA CONTENT; DNA POLYMORPHISM; GENE MAPPING; GENOME; NONHUMAN; STRAIN DIFFERENCE; SYMPOSIUM; TRYPANOSOMA BRUCEI;

TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0030977801     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(97)90189-9     Document Type: Conference Paper

References (27)

1. Cross, G. A. M. (1975). Identification, purification and properties of variant-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei. Parasitology, 71, 393-417.
2. Cross, G. A. M. (1996). Antigenic variation in trypanosomes: secrets surface slowly. Bioessays, 18, 283-291.
3. El-Sayed, N., Alarcon, C. M., Beck, J. C., Sheffield, V. C. & Donelson, J. E. (1995). cDNA expressed sequence tags of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite. Molecular and Biochemical Parasitology, 73, 75-90.
4. Gibson, W. C. (1989). Analysis of a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei. Parasitology, 99, 391-402.
5. Gibson, W. C. & Borst, P. (1986). Size-fractionation of the small chromosomes of Trypanozoon and Nannomonas trypanosomes by pulsed field gel electrophoresis. Molecular and Biochemical Parasitology, 18, 127-140.
6. Gibson, W. C. & Garside, L. (1991). Genetic exchange in Trypanosoma brucei brucei: variable chromosomal location of housekeeping genes in different trypanosome stocks. Molecular and Biochemical Parasitology, 45, 77-90.
7. Gottesdiener, K., Garcia-Anoveros, J., Lee, M. G.-S. & Van der Ploeg, L. H.T. (1990). Chromosome organization of the protozoan Trypanosoma brucei. Molecular and Cellular Biology, 10, 6079-6083.
8. Henriksson, J., Procel, B., Rydaker, M., Ruiz, A., Cazzulo, J., Frasch, A. & Petersson, U. (1995). Trypanosoma cruzi genome project: chromosome-specific markers reveal conserved linkage groups in spite of extensive chromosomal size variation. Molecular and Biochemical Parasitology, 73, 63-74.
9. Ivens, A. C. & Smith, D. F. (1997). Parasite genome analysis. A global map of the Leishmania major genome: prelude to genomic sequencing. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 111-115.
10. Jenni, L., Marti, J., Scheizer, J., Betschart, B., Le Page, R. W. F., Wells, J. M. & Tait, A. (1986). Hybrid formation between African trypanosomes during cyclical transmission. Nature, 322, 173-175.
11. Lanzer, M., de Bruin, D. & Ravetch, J. V. (1993). Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum. chromosome. Nature, 361, 654-657.
12. Lanzer, M., de Bruin, D., Wertheimer, S. P. & Ravetch, J. V. (1994). Organization of chromosomes in Plasmodium falciparum: a model for generating karyotypic diversity. Parasitology Today, 10, 114-117.
13. Matthews, K. R., Shiels, P. G., Graham, S. V., Cowan, C. & Barry, J. D. (1990). Duplicative activation mechanisms of two trypanosome telomeric VSG genes with structurally simple 5′ flanks. Nucleic Acids Research, 18, 7219-7227.
14. Pays, E., Vanhamme, L. & Berberof, M. (1994). Genetic controls for the expression of surface antigens in African trypanosomes. Annual Review of Microbiology, 48, 25-52.
15. Ravel, C., Wincker, P., Blaineau, C., Britto, C., Bastien, P. & Pages, M. (1996). Medium-range restriction maps of five chromosomes of Leishmania infantum and localization of size-variable regions. Genomics, 35, 509-516.
16. Rubio, J. P., Thompson, J. K. & Cowman, A. F. (1996). The var genes of Plasmodium falciparum are located in the subtelomeric region of most chromosomes. EMBO Journal, 15, 4069-4077.
17. Sloof, P., Menke, H. H., Caspers, M. P. M. & Borst, P. (1983). Size fractionation of Trypanosoma brucei DNA: localization of the 177 bp repeat satellite DNA and a variant surface glycoprotein gene in a mini-chromosomal DNA fraction. Nucleic Acids Research, 11, 3889-3901.
18. Tait, A., Buchanan, N., Hide, G. & Turner, C. M. R. (1993). Genetic recombination and karyotype inheritance. In: Genome Analysis of Protozoan Parasites: Proceedings of a Workshop held at ILRAD, Nairobi, Kenya, 11-13 November 1993, Morzaria, S. (editor). Nairobi: ILRAD Press.
19. Tait, A., Buchanan, N., Hide, G. & Turner, C. M. R. (1996). Self-fertilisation in Trypanosoma brucei. Molecular and Biochemical Parasitolagy, 76, 31-42.
20. Turner, C. M. R., Sternberg, J., Smith, E., Buchanan, N., Hide, G. & Tait, A. (1990). Evidence that the mechanism of gene exchange in Trypanosoma brucei involves meiosis and syngamy. Parasitology, 101, 377-386.
21. Turner, C. M. R., Melville, S. E. & Tait, A. (1997). A proposal for karyotype nomenclature in Trypanosoma brucei. Parasitology Today, 13, 5-6.
22. Van der Ploeg, L. H. T., Schwartz, D. C., Cantor, C. R. & Borst, P. (1984a). Antigenic variation in Trypanosoma brucei analysed by electrophoretic separation of chromosome-sized DNA molecules. Cell, 37, 77-84.
23. Van der Ploeg, L. H. T., Cornelissen, A. W. C. A., Michels, P. A. M. & Borst, P. (1984b). Chromosome rearrangements in Trypanosoma brucei. Cell, 39, 213-221.
24. Wells, J. M., Prospero, T. D., Jenni, L. & Le Page, R. W. F. (1987). DNA contents and molecular karyotypes of hybrid Trypanosoma brucei. Molecular and Biochemical Parasitology, 249, 103-116.
25. Williams, R. O., Young, J. R. & Majiwa, P. (1982). Genomic environment of T. brucei VSG genes: presence of a minichromosome. Nature, 299, 417-421.
26. Wincker, P., Ravel, C., Blaineau, C., Pagès, M., Jauffret, Y., Dedet, J. P. & Bastien, P. (1996). The Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species. Nucleic Acids Research, 24, 1688-1694.
27. Zomerdijk, J., Ouellette, M., ten Asbroek, A., Kieft, K., Bommer, A., Clayton, C. & Borst, P. (1990). The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. EMBO Journal, 9, 2791-2801.