The peripheral NK-1/NK-2 receptor antagonist MDL 105,172A inhibits tachykinin-mediated respiratory effects in guinea-pigs

Journal of Autonomic Pharmacology

Volumn 17, Issue 2, 1997, Pages 109-119

  Kudlacz, E M ^a   Knippenberg, R W ^a   Shatzer, S A ^a   Kehne, J H ^a   McCloskey, T C ^a   Burkholder, T P ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 5 AMINOVALERYLSUBSTANCE P [7-11][9 PROLINE 10 (N METHYLLEUCINE)]; CAPSAICIN; INOSITOL PHOSPHATE; MDL 105172A; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR AGONIST; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ A; NEUROKININ A [4-10][8 BETA ALANINE]; NEUROKININ B; NEUROPEPTIDE; PLASMA PROTEIN; RADIOLIGAND; SUBSTANCE P; TACHYKININ; TACHYKININ RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHOSPASM; CELL LINE; CENTRAL NERVOUS SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG PENETRATION; ENANTIOMER; EXTRAVASATION; GERBIL; GUINEA PIG; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NEUROGENIC INFLAMMATION; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; RECEPTOR AFFINITY; RESPIRATORY FUNCTION; SENSORY NERVE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030977628     PISSN: 01441795     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2680.1997.00446.x     Document Type: Article

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