Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis: Activation-induced death can occur without Fas receptor

Journal of Immunology

Volumn 156, Issue 1, 1996, Pages 192-200

  Tuček Szabo, Carolyn L ^a   Andjelić, Sofija ^a   Lacy, Elizabeth ^a   Elkon, Keith B ^b   Nikolić Žugić, Janko ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CELL SURFACE RECEPTOR; MONOCLONAL ANTIBODY CD3; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ETIOLOGY; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE;

ANIMALS; ANTIGENS, CD3; ANTIGENS, CD95; APOPTOSIS; CELL DEATH; CELL MOVEMENT; FAS LIGAND PROTEIN; INTERPHASE; LYMPH NODES; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; MICE, MUTANT STRAINS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; UP-REGULATION;

EID: 0030023574     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Itoh, N., S. Yonehara, A. Ishii, M. Yonehara, S -I. Mizushima, M. Sameshima, A Hase, Y. Seto, and S. Nagata. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233.
2. Watanabe-Fukunaga, R., C. I. Brannan, N. Itoh, S. Yonehara, N. G. Copeland, N. A. Jenkins, and S. Nagata 1992. The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J. Immunol. 148:1274.
3. Smith, C. A., T. Farrah, and R. G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation and death Cell 76:959.
4. Trauth, B. C., C. Klas, A. M. J. Peters, S. Matzku, P. Moller, W. Falk, K.-M. Debatin, and P. J. Krammer. 1989. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245:301.
5. Owen-Schaub, L. B , S. Yonehara, W. L Crump III, and E A. Grimm 1992. DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell. Immunol. 140:197
6. Ogasawara, J., R. Watanabe-Fukunaga, M. Adachi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata 1993. Lethal effect of the anti-Fas antibody in mice Nature 364.806.
7. Schwartz, M L., and B. A. Osborne. 1993. Programmed cell death, apoptosis and killer genes. Immunol. Today 14:582.
8. Andjelić, S., J. Drappa, E. Lacy, K. B. Elkon, and J. Nikolić-Žugić. 1994. The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult αβ thymocytes. Int. Immunol. 6:73.
9. + thymocyte population associated with intact Fas expression on the target. J. Exp. Med. 180:423.
10. Debatin, K.-M., D Suss, and P. H. Krammer. 1994 Differential expression of APO-1 on human thymocytes: implications for negative selection. Eur J. Immunol. 24:753.
11. Singer, G. G., and A K Abbas. 1994. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365.
12. Dhein, J., H. Walczak, C. Baumler, K -M. Debatin, and P. H. Krammer. 1995. Autocrine T-cell suicide mediated by APO-1 (Fas/CD95). Nature 373:438.
13. Brunner, T., R J. Mogll, D LaFace, N. J. Yoo, A. Mahboubl, F. Echeverri, S. J. Martin, W. R Force, D. H. Lynch, C. F. Ware, and D R. Green. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441.
14. Ju, S -T., D. J. Panka, H. Cui, R. Ettinger, M El-Khatib, D. H. Sherr, B. Z. Stanger, and A. Marshak-Rothstein. 1995. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444.
15. Chu, J -L., J. Drappa, A. Parnassa, and K. B. Elkon. 1993. The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon ETn. J. Exp Med. 178:723.
16. Adachi, M., R. Watanabe-Fukunaga, and S. Nagata. 1993. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl. Acad Sci. USA 90:1756.
17. Wu, J., T. Zhou, J. He, and J. D. Mountz. 1993. Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene. J. Exp. Med. 178:461
18. Cohen, P. L., and R. A. Eisenberg. 1991. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9:243.
19. Watanabe-Fukunaga, R., C. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis Nature 356:314.
20. Sobel, E. S., V. N. Kakkanaiah, M. Kakkanaiah, R. L. Cheek, P. L. Cohen, and R. A. Eisenberg 1994 T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted. J. Immunol. 152:6011.
21. Chu, J.-L., P. Ramos, A. Rosendorff, J. Nikolić-Žugić, E. Lacy, A Matsuzawa, and K. B. Elkon. 1995. Massive up-regulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft versus host disease-like wasting syndrome J Exp. Med. 181:393.
22. Nagata, S., and T Suda. 1995. Fas and Fas ligand: lpr and gld mutations Immunol. Today 16:39.
23. Drappa, J., N. Brot, and K. Elkon. 1993 The Fas protein is expressed at high levels on double positive thymocytes and activated mature T cells in normal but not MRL/lpr mice. Proc. Natl. Acad. Sci. USA 90:10340.
24. Miyawaki, T., T. Uehara, R. Nibu, T. Tsuji, A. Yachie, S. Yonehara, and N. Taniguchi. 1992. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood J. Immunol 149:3753.
25. Klas, C., K.-M. Debatin, R. R Jonker, and P. H. Krammer. 1993 Activation interferes with the APO-1 pathway in mature human T cells. Int. Immunol. 5.625.
26. Wofsy, D., R Hardy, and W. Seaman. 1984. The proliferative cells in autoimmune MRL/lpr mice lacking L3T4. an antigen in "helper" T cells that is involved in the response to class II major histocompatibility antigens. J. Immunol. 132:2686.
27. Budd, R. C., M. Schreyer, G C. Miescher, and H. R. McDonald. 1987. T cell lineages in the thymus of lpr/lpr mice: evidence for parallel pathways of normal and abnormal T cell development J Immunol. 193:2200.
28. cg, that complements the gld gene m induction of lymphadenopathy in the mouse J Exp. Med 171:519
29. Kelly, K. A., and R Scollay. 1992. Analysis of recent thymic emigrants with subset- and maturity-related markers. Int. Immunol. 2:419.
30. Nicolleti, I., C. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 134:271.
31. Onel, K. B., C. L Tuček-Szabo, D. Ashany, E. Lacy, J. Nikolić-Žugić, and K Elkon. 1995. Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell tolerance.
32. Janeway, C. A., Jr. 1991. Selective elements for the Vβ region of the T cell receptor: MIs and the bacterial toxic mitogens. Adv. Immunol 50:1.
33. Herman, A., J. W. Kappler, P. Marrack, and A. Pullen. 1991. Superantigens, mechanisms of T cell stimulation and role in immune responses. Annu. Rev Immunol. 9:745.
34. + T cells in mice tolerant to Staphylococcus aureus enterotoxin B Nature 349 245.
35. + peripheral T cells responding to staphylococcal enterotoxin B in vivo Eur. J. Immunol. 21:1963
36. Altman, A., A. N. Theofilopoulos, R. Weiner, D. H. Katz, and F. J. Dixon. 1981. Analysis of T cell function in autoimmune murine strains: defects in production of and responsiveness to interleukin-2. J. Exp. Med. 154:791.
37. - T cells of lpr mice. Cell Immunol. 123:396.
38. Van Houten, N., and R C. Budd. 1992. Accelerated programmed cell death of MRL-lpr/lpr 1 lymphocytes. J Immunol. 149:2513.
39. - thymocytes by the anti-Fas antibody. J. Exp. Med. 181:485
40. Wang, Z-Q , A. Dudhane, T. Orlikowsky, K. Clarke, X. Li, Z. Darzynkiewicz, and M. K. Hoffman. 1994. CD4 engagement induces Fas antigen-dependent apoptosis of T cells in vivo. Eur. J. Immunol. 24:1549.
41. Kim, C., K. A. Siminovitch, and A. Ochi. 1991. Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment. J. Exp. Med. 174:1431
42. Scott, D. E , W J. Kisch, and A D. Steinberg. 1993. Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice. J. Immunol. 150:664.
43. Russell, J. H., B. Rush, C Weaver, and R. Wang 1993. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl Acad. Sci. USA 90:4409.
44. + T lymphocytes from MRL/lpr truce are resistant to receptor-mediated tolerance and apoptosis. J Immunol. 151:7233.
45. Gillette-Ferguson, I., and C. L. Sidman. 1994 A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice. Eur J. Immunol. 24:1181
46. Papiernik, M , C Pontoux, and P. Golstein. 1995. Nonexclusive Fas control and age-dependence of viral superantigen-induced clonal deletion in lupus-prone mice. Eur. J Immunol. In press.
47. Renno, T , M. Hahne, and H. R. MacDonald. 1995. Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo. J. Exp. Med. 181 2283.
48. + and abnormal lpr and gld cell populations J. Exp. Med. 170:1869.