Modified antisense oligonucleotides directed against tumor necrosis factor receptor type I inhibit tumor necrosis factor α-mediated functions

Biochemistry

Volumn 36, Issue 20, 1997, Pages 6033-6045

  Ojwang, Joshua O ^a   Mustain, Shawn D ^a   Marshall, Hélène B ^a   Rao, T Sudhakar ^a   Chaudhary, Nilabh ^a   Walker, David A ^a   Hogan, Michael E ^b   Akiyama, Taishin ^b   Revankar, Ganapathi R ^a   Peyman, Anusch ^c   Uhlmann, Eugen ^c   Rando, Robert F ^a  

^a Antigenics Inc   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPID; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR BINDING;

ANTIGENS, CD; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; FIBROBLASTS; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; OLIGONUCLEOTIDES, ANTISENSE; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; THIONUCLEOTIDES; TOXICITY TESTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030971746     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970124x     Document Type: Article

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