The SAR of UK-78,282: A novel blocker of human T cell Kv1.3 potassium channels

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 8, 1997, Pages 1047-1052

  Burgess, Laurence E ^a,b   Koch, Kevin ^a,b   Cooper, Kelvin ^a   Biggers, Michael S ^a   Ramchandani, Mukesh ^a   Smitrovich, Jacqueline H ^a   Gilbert, Eric J ^a   Bruns, Matthew J ^a   Mather, Robert J ^a   Donovan, Carol B ^a   Hanson, Douglas C ^a  

^a PFIZER INC   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 BENZHYDRYLOXYMETHYL 1 [3 (4 METHOXYPHENYL)PROPYL]PIPERIDINE; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; RUBIDIUM 86; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; HUMAN; HUMAN CELL; IN VITRO STUDY; ION CURRENT; LIPOPHILICITY; PATCH CLAMP; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

EID: 0030970111     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00163-7     Document Type: Article

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