Persistent eNOS in lung hypoplasia caused by left pulmonary artery ligation in the ovine fetus

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 5 16-5, 1997, Pages

  Tajchman, Urszula W ^a   Tuder, Rubin M ^b   Horan, Marilee ^a   Parker, Thomas A ^a   Abman, Steven H ^a,c  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL   (United States)

Author keywords

Angiogenesis; Endothelial nitric oxide synthase; Endothelium; Lung development; Nitric oxide; Pulmonary blood flow; Pulmonary circulation; Pulmonary hypertension; Shear stress; Vasculature

Indexed keywords

NITRIC OXIDE SYNTHASE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY LIGATION; ARTICLE; CELL MATURATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; LUNG BLOOD FLOW; LUNG CIRCULATION; LUNG DEVELOPMENT; LUNG HYPOPLASIA; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; SHEEP;

EID: 0030969038     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.5.l969     Document Type: Article

References (44)

1. Abman, S. H., and F. J. Accurso. Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H626-H634, 1989.
2. Abman, S. H., B. A. Chatfield, S. L. Hall, and I. F. McMurtry. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1921-H1927, 1990.
3. Adnot, S., B. Raffestin, S. Eddahibi, P. Braquet, and P. Chabrier. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87: 155-162, 1991.
4. Alcorn, D., T. M. Adamson, T. F. Lambert, J. E. Maloney, B. C. Kitchie, and P. M. Robinson. Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung. J. Anat. 123: 649-660, 1977.
5. Alcorn, D., T. M. Adamson, J. E. Maloney, and P. M. Robinson. Morphological effects of chronic bilateral phrenectomy or vagotomy in the fetal lamb lung. J. Anat. 130: 683-695, 1980.
6. Archer, S., V. Hampl, Z. McKenzie, D. Nelson, J. Huang, P. J. Shultz, and E. K. Weir. Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature. Semin. Respir. Crit. Care Med. 15: 179-189, 1994.
7. Arnal, J.-F., J. Yamin, S. Dockery, and D. G. Harrison. Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth. Am. J. Physiol. 267 (Cell Physiol. 36): C1381-C1388, 1994.
8. Bradford, M. A. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254, 1976.
9. Buttery, L. D. K., D. R. Springall, S. P. Andrade, V. Riveros-Morenos, I. Hart, P. J. Piper, and J. M. Polak. Induction of nitric oxide synthase in the neo-vasculature of experimental tumors in mice. J. Pathol. 171: 311-319, 1993.
10. Cassin, S., G. S. Dawes, J. C. Mott, B. B. Ross, and L. B. Strang. Vascular resistance of the foetal and newly ventilated lung of the lamb. J. Physiol. Lond. 171: 61-79, 1964.
11. Cooke, J. P., E. Rossitch, N. A. Andon, L. Loscalzo, and V. J. Dzau. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J. Clin. Invest. 88: 1663-1671, 1991.
12. Cornfield, D. N., B. A. Chatfield, J. A. McQueston, I. F. McMurtry, and S. H. Abman. Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H1474-H1481, 1992.
13. Dawes, G. S. Control of the pulmonary circulation in the fetus and newborn. In: The Pulmonary Circulation and Interstitial Space, edited by A. Fishman and H. Hecht. Chicago, IL: Univ. of Chicago Press, 1969, p. 293-304.
14. deLorimier, A. A., A. G. Manus, and W. S. Tyler. Morphometry of normal and hypoplastic lungs in newborn lambs. Curr. Top. Surg. Res. 1: 431-442, 1969.
15. Dinh-Xuan, A. T. Disorders of endothelium-dependent relaxation in pulmonary disease. Circulation 87: V81-V87, 1993.
16. Docimo, S. G., R. K. Crone, P. Davies, L. Reid, A. B. Retik, and J. Mandell. Pulmonary development in the fetal lamb: morphometric study of the alveolar phase. Anat. Rec. 229: 495-498, 1991.
17. Halbower, A. C., R. M. Tuder, W. A. Franklin, J. S. Pollock, U. Forstermann, and S. H. Abman. Maturation-related changes in endothelial nitric oxide synthase immunolocalization in developing ovine lung. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L585-L591, 1994.
18. Haworth, S. G., S. A. McKenzie, and M. L. Fitzpatrick. Alveolar development after ligation of left pulmonary artery in newborn pig: clinical relevance to unilateral pulmonary artery. Thorax 36: 938-943, 1981.
19. Inoue, N., R. C. Venema, H. S. Sayegh, Y. Ohara, T. J. Murphy, and D. G. Harrison. Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-β1. Arteriosclerosis Thromb. Vasc. Biol. 15: 1255-1261, 1995.
20. Isaacson, T. C., V. Hampl, E. K. Weir, D. P. Nelson, and S. L. Archer. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J. Appl. Physiol. 76: 933-940, 1994.
21. Karamanoukian, H. L., P. L. Glick, D. T. Wilcox, J. E. Rossman, and R. G. Azizkhan. Pathophysiology of congenital diaphragmatic hernia X: localization of nitric oxide synthase in the intima of pulmonary artery trunks of lambs with surgically created congenital diaphragmatic hernia. J. Pediatr. Surg. 30: 5-9, 1995.
22. Kinsella, J. P., D. D. Ivy, and S. H. Abman. Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1955-H1961, 1994.
23. Kostyk, S. K., S. Kourembanas, E. L. Wheeler, D. Medeiros, L. P. McQuillan, P. A. D'Amore, and S. J. Braunhut. Basic fibroblast growth factor increases nitric oxide synthase production in bovine endothelial cells. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H1583-H1589, 1995.
24. Le Cras, T. D., C. Xue, A. Rengasamy, and R. A. Johns. Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L164-L170, 1996.
25. Miller, V. M., L. L. Aarhus, and P. M. Vanhoutte. Modulation of endothelium-dependent responses by chronic alterations of blood flow. Am. J. Physiol. 251 (Heart Circ. Physiol. 20): H520-H527, 1986.
26. Morbidelli, L., C. H. Chang, J. G. Douglas, H. J. Granger, F. Ledda, and M. Ziche. NO mediates mitogenic effect of VEGF on coronary vascular endothelium. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H411-H415, 1996.
27. North, A. J., K. S. Lau, T. S. Brannon, L. C. Wu, L. B. Wells, Z. German, and P. W. Shaul. Oxygen upregulates nitric oxide synthase gene expression in ovine fetal pulmonary artery endothelial cells. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L643-L649, 1996.
28. North, A. J., F. R. Moya, M. R. Mysore, V. L. Thomas, L. B. Wells, L. C. Wu, and P. W. Shaul. Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia. Am. J. Respir. Cell Mol. Biol. 13: 676-682, 1995.
29. North, A. J., R. A. Star, T. S. Brannon, K. Ujiie, L. B. Wells, C. J. Lowenstein, S. H. Snyder, and P. W. Shaul. Nitric oxide synthase type I and type III gene expression are developmentally regulated in rat lung. Am. J. Physiol. 266 (Lung Cell. Mol. Physiol. 10): L635-L641, 1994.
30. Pipili-Synetos, E., E. Sakkoula, and M. E. Maragoudakis. Nitric oxide is involved in the regulation of angiogenesis. Br. J. Pharmacol. 108: 855-857, 1993.
31. Pollock, J. S., M. Nakane, L. D. K. Buttery, A. Martinez, D. Springall, J. M. Polak, U. Forstermann, and F. Murad. Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies. Am. J. Physiol. 265 (Cell Physiol. 34): C1379-C1387, 1993.
32. Pringle, K. C., J. W. Turner, J. C. Schofield, and R. T. Soper. Creation and repair of diaphragmatic hernia in the fetal lamb: lung development and morphology. J. Pediatr. Surg. 19: 131-140, 1984.
33. Ranjan, V., Z. Xiao, and S. L. Diamond. Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H550-H555, 1995.
34. Rudolph, A. M., M. A. Heymann, and A. B. Lewis. Physiology and pharmacology of the pulmonary circulation in the fetus and newborn. In: Development of the Lung, edited by W. Hodson. New York: Dekker, 1977, p. 497-523.
35. 2+-independent nitric oxide synthases. FEBS Lett. 291: 145-149, 1991.
36. Sessa, W. C., K. Pritchard, N. Seyedi, J. Wang, and T. H. Hintze. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res. 74: 349-353, 1994.
37. Shaul, P. W., M. A. Farrar, and T. M. Zellers. Oxygen modulates endothelium-derived relaxing factor production in fetal pulmonary arteries. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H355-H364, 1992.
38. Suen, H. C., K. D. Bloch, and P. K. Donahoe. Antenatal glucocorticoid corrects pulmonary immaturity in experimentally induced congenital diaphragmatic hernia in rats. Pediatr. Res. 35: 523-529, 1994.
39. Tenbrinck, R., D. Tibboel, J. Gaillard, D. Kluth, A. Bos, B. Lachmann, and J. Molenaar. Experimentally-induced congenital diaphragmatic hernia in rats. J. Pediatr. Surg. 25: 426-429, 1990.
40. Uematsu, M., J. P. Navas, K. Nishida, Y. Ohara, T. J. Murphy, R. W. Alexander, R. M. Nerem, and D. G. Harrison. Mechanisms of endothelial cell NO synthase induction by shear stress (Abstract). Circulation 88: 1184, 1993.
41. Wallen, L. D., S. F. Perry, J. T. Alston, and J. E. Maloney. Morphometric study of the role of pulmonary arterial flow in fetal lung growth in sheep. Pediatr. Res. 27: 122-127, 1990.
42. Xue, C., A. Rengasamy, T. D. LeCras, P. A. Koberna, G. C. Dailey, and R. A. Johns. Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation of NOS by chronic hypoxia. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L667-L678, 1994.
43. Xue, C., P. R. Reynolds, and R. A. Johns. Developmental expression of NOS isoforms in fetal rat lung: implications for transitional circulation and pulmonary angiogenesis. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L88-L100, 1996.
44. Ziche, M., L. Morbidelli, E. Macini, S. Amerini, H. J. Granger, C. A. Maggi, P. Geppetti, and F. Ledda. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J. Clin. Invest. 94: 2036-2044, 1994.