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Volumn 327, Issue 1, 1997, Pages 1-9

Antiparkinsonian and other motor effects of flupirtine alone and in combination with dopaminergic drugs

Author keywords

Catalepsy; Flupirtine; L DOPA (L dihydroxyphenylalanine); Locomotion; NMDA receptor, antagonistic; Parkinson's disease

Indexed keywords

BENSERAZIDE; FLUPIRTINE; HALOPERIDOL; LEVODOPA; NEUROLEPTIC AGENT;

EID: 0030965170     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)89671-9     Document Type: Article
Times cited : (24)

References (48)
  • 1
    • 0026539328 scopus 로고
    • Competitive and non-competitive NMDA-receptor antagonists in spatial learning tasks
    • Bischoff C., Tiedtke P.I. Competitive and non-competitive NMDA-receptor antagonists in spatial learning tasks. Eur. J. Pharmacol. 213:1992;269.
    • (1992) Eur. J. Pharmacol. , vol.213 , pp. 269
    • Bischoff, C.1    Tiedtke, P.I.2
  • 2
    • 0028564953 scopus 로고
    • Flupirtine protects against ischaemic retinal dysfunction in rats
    • Block F., Pergande G., Schwarz M. Flupirtine protects against ischaemic retinal dysfunction in rats. NeuroReport. 5:1994;2630.
    • (1994) NeuroReport , vol.5 , pp. 2630
    • Block, F.1    Pergande, G.2    Schwarz, M.3
  • 3
    • 0030937923 scopus 로고    scopus 로고
    • Flupirtine reduces functional and morphological consequences induced by global ischemia in rats
    • Block F., Pergande G., Schwarz M. Flupirtine reduces functional and morphological consequences induced by global ischemia in rats. Brain Res. 754:1997;279.
    • (1997) Brain Res. , vol.754 , pp. 279
    • Block, F.1    Pergande, G.2    Schwarz, M.3
  • 4
    • 0028126940 scopus 로고
    • Competitive NMDA receptor antagonists attenuate the behavioural and neurochemical effects of amphetamine in mice
    • Bristow L.J., Thorn L., Tricklebank M.D., Hutson P.H. Competitive NMDA receptor antagonists attenuate the behavioural and neurochemical effects of amphetamine in mice. Eur. J. Pharmacol. 264:1994;353.
    • (1994) Eur. J. Pharmacol. , vol.264 , pp. 353
    • Bristow, L.J.1    Thorn, L.2    Tricklebank, M.D.3    Hutson, P.H.4
  • 5
    • 0026498964 scopus 로고
    • Differential behavioural effects of competitive and non-competitive NMDA receptor antagonists in rats
    • Bubser M., Keseberg U., Notz P.K., Schmidt W.J. Differential behavioural effects of competitive and non-competitive NMDA receptor antagonists in rats. Eur. J. Pharmacol. 229:1992;75.
    • (1992) Eur. J. Pharmacol. , vol.229 , pp. 75
    • Bubser, M.1    Keseberg, U.2    Notz, P.K.3    Schmidt, W.J.4
  • 6
    • 0024360965 scopus 로고
    • Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice
    • Carlsson M., Carlsson A. Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice. J. Neural Transm. 77:1989;65.
    • (1989) J. Neural Transm. , vol.77 , pp. 65
    • Carlsson, M.1    Carlsson, A.2
  • 7
    • 0025363344 scopus 로고
    • Interactions between glutamatergic and monoaminergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease
    • Carlsson M., Carlsson A. Interactions between glutamatergic and monoaminergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends Neurosci. 13:1990;272.
    • (1990) Trends Neurosci. , vol.13 , pp. 272
    • Carlsson, M.1    Carlsson, A.2
  • 8
    • 0342475778 scopus 로고    scopus 로고
    • Striatal glutamatergic dysfunction and extrapyramidal motor behaviour
    • Chase T.M., Papa S.M., Verhagen Metman L., Mourdian M.M. Striatal glutamatergic dysfunction and extrapyramidal motor behaviour. Behav. Pharmacol. 7(Suppl. 1):1996;14.
    • (1996) Behav. Pharmacol. , vol.7 , Issue.SUPPL. 1 , pp. 14
    • Chase, T.M.1    Papa, S.M.2    Verhagen Metman, L.3    Mourdian, M.M.4
  • 9
    • 0027456560 scopus 로고
    • Flupirtine: A review of its pharmacological properties and therapeutic efficacy in pain states
    • Friedel H.A., Fitton A. Flupirtine: a review of its pharmacological properties and therapeutic efficacy in pain states. Drugs. 45:1993;548.
    • (1993) Drugs , vol.45 , pp. 548
    • Friedel, H.A.1    Fitton, A.2
  • 10
    • 0026005169 scopus 로고
    • N-Methyl-D-aspartate antagonists in the treatment of Parkinson's disease
    • Greenamyre J.T., O'Brien C.F. N-Methyl-D-aspartate antagonists in the treatment of Parkinson's disease. Arch. Neurol. 48:1991;977.
    • (1991) Arch. Neurol. , vol.48 , pp. 977
    • Greenamyre, J.T.1    O'Brien, C.F.2
  • 11
    • 0027482197 scopus 로고
    • The non-NMDA glutamate receptor antagonist GYKI 52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine
    • Hauber W., Andersen R. The non-NMDA glutamate receptor antagonist GYKI 52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine. Naunyn-Schmiedeberg's Arch. Pharmacol. 348:1993;486.
    • (1993) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.348 , pp. 486
    • Hauber, W.1    Andersen, R.2
  • 13
    • 0002845329 scopus 로고
    • Brain dopamine in Parkinson's disease and other neurological disturbances
    • In: Horn, A.S., Korf, J., Westerink, B.M.C. (Eds.), Academic Press, London
    • Hornykiewicz, O., 1979. Brain dopamine in Parkinson's disease and other neurological disturbances. In: Horn, A.S., Korf, J., Westerink, B.M.C. (Eds.), The Neurobiology of Dopamine. Academic Press, London, p. 633.
    • (1979) The Neurobiology of Dopamine , pp. 633
    • Hornykiewicz, O.1
  • 14
    • 0025146826 scopus 로고
    • NMDA antagonists potentiate antiparkinsonian actions of L-DOPA in monoamine-depleted rats
    • Klockgether T., Turski L. NMDA antagonists potentiate antiparkinsonian actions of L-DOPA in monoamine-depleted rats. Ann. Neurol. 28:1990;539.
    • (1990) Ann. Neurol. , vol.28 , pp. 539
    • Klockgether, T.1    Turski, L.2
  • 15
    • 0026790475 scopus 로고
    • The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior
    • Kretschmer B.D., Zadow B., Volz T.L., Volz L., Schmidt W.J. The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior. J. Neural Transm. [GenSect.]. 87:1992;23.
    • (1992) J. Neural Transm. [GenSect.] , vol.87 , pp. 23
    • Kretschmer, B.D.1    Zadow, B.2    Volz, T.L.3    Volz, L.4    Schmidt, W.J.5
  • 17
    • 0029024950 scopus 로고
    • Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats
    • Kretschmer B.D., Bubser M., Schmidt W.J. Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats. Eur. J. Pharmacol. 280:1995;37.
    • (1995) Eur. J. Pharmacol. , vol.280 , pp. 37
    • Kretschmer, B.D.1    Bubser, M.2    Schmidt, W.J.3
  • 18
    • 0025017052 scopus 로고
    • Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats
    • Mehta A.K., Ticku M.K. Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats. Life Sci. 46:1990;37.
    • (1990) Life Sci. , vol.46 , pp. 37
    • Mehta, A.K.1    Ticku, M.K.2
  • 22
    • 0030357771 scopus 로고    scopus 로고
    • Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: Induction and pharmacological intervention
    • in: Kuchine, Y., Müller, W.E.G. (Eds.), Springer-Verlag, Berlin
    • Müller, W.E.G., Pergande, G., Schleger, C., Ushijima, H., Perovic, S., 1996b. Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention. in: Kuchine, Y., Müller, W.E.G. (Eds.), Apoptosis. Springer-Verlag, Berlin, p. 44.
    • (1996) Apoptosis , pp. 44
    • Müller, W.E.G.1    Pergande, G.2    Schleger, C.3    Ushijima, H.4    Perovic, S.5
  • 23
    • 0031014346 scopus 로고    scopus 로고
    • Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: Implications for treatment of AIDS patients
    • Müller W.E.G., Dobmeyer J.M., Dobmeyer T.S., Pergande G., Perovic S., Leuck J., Rossol R. Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: implications for treatment of AIDS patients. Cell Death Diff. 4:1997;51.
    • (1997) Cell Death Diff. , vol.4 , pp. 51
    • Müller, W.E.G.1    Dobmeyer, J.M.2    Dobmeyer, T.S.3    Pergande, G.4    Perovic, S.5    Leuck, J.6    Rossol, R.7
  • 24
    • 0021811864 scopus 로고
    • Einfluß des neuen Analgetikums Flupirtin auf die psychomotorische Leistungsfähigkeit des Menschen
    • Müller-Limmroth W. Einfluß des neuen Analgetikums Flupirtin auf die psychomotorische Leistungsfähigkeit des Menschen. Arzneim.-Forsch./Drug Res. 35:1985;1089.
    • (1985) Arzneim.-Forsch./Drug Res. , vol.35 , pp. 1089
    • Müller-Limmroth, W.1
  • 25
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney J.W., Labruyere J., Price M.T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science. 244:1989;1360.
    • (1989) Science , vol.244 , pp. 1360
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 26
    • 0028578022 scopus 로고
    • Immuno-histochemical evidence for flupirtine acting as an antagonist on the N-methyl-D-aspartate and homocysteic acid-induced release of GABA in the rabbit retina
    • Osborne N.N., Pergande G., Block F., Schwarz M. Immuno-histochemical evidence for flupirtine acting as an antagonist on the N-methyl-D-aspartate and homocysteic acid-induced release of GABA in the rabbit retina. Brain Res. 667:1994;291.
    • (1994) Brain Res. , vol.667 , pp. 291
    • Osborne, N.N.1    Pergande, G.2    Block, F.3    Schwarz, M.4
  • 28
    • 0028670691 scopus 로고
    • The triaminopyridine flupirtine prevents cell death in rat cortical cells induced by N-methyl-D-aspartate and gp120 of HIV-1
    • Perovic S., Schleger C., Pergande G., Iskric S., Ushijima H., Rytik P., Müller W.E.G. The triaminopyridine flupirtine prevents cell death in rat cortical cells induced by N-methyl-D-aspartate and gp120 of HIV-1. Eur. J. Pharmacol. 288:1994;27.
    • (1994) Eur. J. Pharmacol. , vol.288 , pp. 27
    • Perovic, S.1    Schleger, C.2    Pergande, G.3    Iskric, S.4    Ushijima, H.5    Rytik, P.6    Müller, W.E.G.7
  • 30
    • 0022725590 scopus 로고
    • Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
    • Robinson T.E., Becker J.B. Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res. Rev. 11:1986;157.
    • (1986) Brain Res. Rev. , vol.11 , pp. 157
    • Robinson, T.E.1    Becker, J.B.2
  • 31
    • 0027418153 scopus 로고
    • The sigma receptor ligand 1,3-di-(2-tolyl)guanidine in animal models of schizophrenia
    • Rückert N.G.H., Schmidt W.J. The sigma receptor ligand 1,3-di-(2-tolyl)guanidine in animal models of schizophrenia. Eur. J. Pharmacol. 233:1993;261.
    • (1993) Eur. J. Pharmacol. , vol.233 , pp. 261
    • Rückert, N.G.H.1    Schmidt, W.J.2
  • 33
    • 0022446858 scopus 로고
    • Intrastriatal injection of DL-2-amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine
    • Schmidt W.J. Intrastriatal injection of DL-2-amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine. Psychopharmacology. 90:1986;123.
    • (1986) Psychopharmacology , vol.90 , pp. 123
    • Schmidt, W.J.1
  • 34
    • 0029414732 scopus 로고
    • Balance of transmitter activities in the basal ganglia loops
    • Schmidt W.J. Balance of transmitter activities in the basal ganglia loops. J. Neural Transm. 46(Suppl.):1995;67.
    • (1995) J. Neural Transm. , vol.46 , Issue.SUPPL. , pp. 67
    • Schmidt, W.J.1
  • 35
    • 0024403639 scopus 로고
    • Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats
    • Schmidt W.J., Bubser M. Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats. Pharmacol. Biochem. Behav. 32:1989;621.
    • (1989) Pharmacol. Biochem. Behav. , vol.32 , pp. 621
    • Schmidt, W.J.1    Bubser, M.2
  • 36
    • 0023765604 scopus 로고
    • Behavioural effects of N-methyl-D-aspartate in the anterodorsal striatum of the rat
    • Schmidt W.J., Bury D. Behavioural effects of N-methyl-D-aspartate in the anterodorsal striatum of the rat. Life Sci. 43:1988;545.
    • (1988) Life Sci. , vol.43 , pp. 545
    • Schmidt, W.J.1    Bury, D.2
  • 38
    • 0027956478 scopus 로고
    • N-Methyl-D-aspartate (NMDA)-mediated muscle relaxant action of flupirtine in rats
    • Schwarz M., Block F., Pergande G. N-Methyl-D-aspartate (NMDA)-mediated muscle relaxant action of flupirtine in rats. NeuroReport. 5:1994;1981.
    • (1994) NeuroReport , vol.5 , pp. 1981
    • Schwarz, M.1    Block, F.2    Pergande, G.3
  • 39
    • 0028985760 scopus 로고
    • 2-adrenergic mechanisms are involved in the depressant action of flupirtine on spinal reflexes in rats
    • 2-adrenergic mechanisms are involved in the depressant action of flupirtine on spinal reflexes in rats. Eur. J. Pharmacol. 276:1995;247.
    • (1995) Eur. J. Pharmacol. , vol.276 , pp. 247
    • Schwarz, M.1    Schmitt, T.2    Pergande, G.3    Block, F.4
  • 42
    • 0026084463 scopus 로고
    • Pharmacological profile of flupirtine, a novel centrally acting, non-opioid analgesic drug
    • Szelenyi I., Nickel B. Pharmacological profile of flupirtine, a novel centrally acting, non-opioid analgesic drug. Agents Actions. 32(Suppl.):1991;119.
    • (1991) Agents Actions , vol.32 , Issue.SUPPL. , pp. 119
    • Szelenyi, I.1    Nickel, B.2
  • 45
    • 0029990395 scopus 로고    scopus 로고
    • Procedural examination of behavioural sensitisation to morphine: Lack of blockade by MK-801, occurrence of sensitised sniffing, and evidence for cross-sensitisation between morphine and MK-801
    • Tzschentke T.M., Schmidt W.J. Procedural examination of behavioural sensitisation to morphine: lack of blockade by MK-801, occurrence of sensitised sniffing, and evidence for cross-sensitisation between morphine and MK-801. Behav. Pharmacol. 7:1996;169.
    • (1996) Behav. Pharmacol. , vol.7 , pp. 169
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 48
    • 0027955445 scopus 로고
    • The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy
    • Zadow B., Schmidt W.J. The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy. Naunyn-Schmiedeberg's Arch. Pharmacol. 349:1994;61.
    • (1994) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.349 , pp. 61
    • Zadow, B.1    Schmidt, W.J.2


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