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Volumn 138, Issue 4, 1997, Pages 1456-1463

Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from deoxyribonucleic acid: Its role in dominant negative action

Author keywords

[No Author keywords available]

Indexed keywords

DNA; LIOTHYRONINE; THYROID HORMONE RECEPTOR;

EID: 0030960827     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.4.5067     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 0027241002 scopus 로고
    • The syndromes of resistance to thyroid hormone
    • Refetoff S, Weiss RE, Usala SJ 1993 The syndromes of resistance to thyroid hormone. Endocr Rev 14:348-399
    • (1993) Endocr Rev , vol.14 , pp. 348-399
    • Refetoff, S.1    Weiss, R.E.2    Usala, S.J.3
  • 2
    • 0028873268 scopus 로고
    • New developments in clinical and genetic aspects of thyroid hormone resistance syndromes
    • Usala SJ 1995 New developments in clinical and genetic aspects of thyroid hormone resistance syndromes. The Endocrinologist 5:68-76
    • (1995) The Endocrinologist , vol.5 , pp. 68-76
    • Usala, S.J.1
  • 4
    • 0028911237 scopus 로고
    • New insights into the structure and function of the thyroid hormone receptor
    • Cheng S-y 1995 New insights into the structure and function of the thyroid hormone receptor. J Biomed Sci 2:77-89
    • (1995) J Biomed Sci , vol.2 , pp. 77-89
    • Cheng, S.-Y.1
  • 5
    • 0025854410 scopus 로고
    • An essential role of domain D in the hormone-binding activity of human β1 thyroid hormone nuclear receptor
    • Lin KH, Parkison C, McPhie P, Cheng SY 1991 An essential role of domain D in the hormone-binding activity of human β1 thyroid hormone nuclear receptor. Mol Endocrinol 5:485-492
    • (1991) Mol Endocrinol , vol.5 , pp. 485-492
    • Lin, K.H.1    Parkison, C.2    McPhie, P.3    Cheng, S.Y.4
  • 6
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf DJ, Evans RM 1995 The RXR heterodimers and orphan receptors. Cell 83:841-850
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 8
    • 0029741543 scopus 로고    scopus 로고
    • Identification of naturally occurring dominant negative mutants of thyroid hormone α1 and β1 receptors in a human hepatocellular carcinoma cell line
    • Lin KH, Zhu XG, Shieh HY, Hsu HC, Chen ZT, McPhie P, Cheng S-y 1996 Identification of naturally occurring dominant negative mutants of thyroid hormone α1 and β1 receptors in a human hepatocellular carcinoma cell line. Endocrinology 137:4073-4081
    • (1996) Endocrinology , vol.137 , pp. 4073-4081
    • Lin, K.H.1    Zhu, X.G.2    Shieh, H.Y.3    Hsu, H.C.4    Chen, Z.T.5    McPhie, P.6    Cheng, S.-Y.7
  • 11
    • 0028037369 scopus 로고
    • Molecular mechanisms of dominant negative activity by nuclear hormone receptors
    • Yen P, Chin WW 1994 Molecular mechanisms of dominant negative activity by nuclear hormone receptors. Mol Endocrinol 8:1450-1454
    • (1994) Mol Endocrinol , vol.8 , pp. 1450-1454
    • Yen, P.1    Chin, W.W.2
  • 12
    • 0028896912 scopus 로고
    • Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbAa2 and peroxisome proliferation-activated receptor: Evidence for different mechanisms of inhibition
    • Meier-Heusler SC, Zhu XG, Juge-Aubry C, Pernin A, Burger AG, Cheng SY, Meier CA 1995 Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbAa2 and peroxisome proliferation-activated receptor: evidence for different mechanisms of inhibition. Mol Cell Endocrinol 107:35-66
    • (1995) Mol Cell Endocrinol , vol.107 , pp. 35-66
    • Meier-Heusler, S.C.1    Zhu, X.G.2    Juge-Aubry, C.3    Pernin, A.4    Burger, A.G.5    Cheng, S.Y.6    Meier, C.A.7
  • 13
    • 0030023159 scopus 로고    scopus 로고
    • Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone b1 receptors: The important role of the wild-type/mutant receptor heterodimer
    • Zhu XG, Yu CL, McPhie P, Wong R, and Cheng S-y 1996 Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone b1 receptors: the important role of the wild-type/mutant receptor heterodimer. Endocrinology 137:712-721
    • (1996) Endocrinology , vol.137 , pp. 712-721
    • Zhu, X.G.1    Yu, C.L.2    McPhie, P.3    Wong, R.4    Cheng, S.-Y.5
  • 14
    • 0027963512 scopus 로고
    • Stimulation of proliferation by 3,3′,5-triiodo-L-thyronine in poorly differentiated hyman hepatocarcinoma cells overexpressing β1 thyroid hormone receptor
    • Lin KH, Lin YW, Parkison C, and Cheng S-y 1994 Stimulation of proliferation by 3,3′,5-triiodo-L-thyronine in poorly differentiated hyman hepatocarcinoma cells overexpressing β1 thyroid hormone receptor. Cancer Lett 85:189-194
    • (1994) Cancer Lett , vol.85 , pp. 189-194
    • Lin, K.H.1    Lin, Y.W.2    Parkison, C.3    Cheng, S.-Y.4
  • 15
    • 0025233788 scopus 로고
    • Hormone and DNA binding activity of a purified thyroid hormone nuclear receptor expressed in Escherichia coli
    • Lin KH, Fukuda T, Cheng S-y 1990 Hormone and DNA binding activity of a purified thyroid hormone nuclear receptor expressed in Escherichia coli. J Biol Chem 265:5161-5165
    • (1990) J Biol Chem , vol.265 , pp. 5161-5165
    • Lin, K.H.1    Fukuda, T.2    Cheng, S.-Y.3
  • 16
    • 0026613089 scopus 로고
    • 3-receptor / retinoid × receptor heterodimer binding to DNA
    • 3-receptor / retinoid × receptor heterodimer binding to DNA. J Biol Chem 267:23248-23252
    • (1992) J Biol Chem , vol.267 , pp. 23248-23252
    • Yen, P.M.1    Sugawara, A.2    Chin, W.W.3
  • 17
    • 0027253629 scopus 로고
    • Different dimerization activities of alpha and beta thyroid hormone receptor isoforms
    • Darling DS, Carter RL, Yen PM, Welborn JM, Chin WW, Umeda PK 1943 Different dimerization activities of alpha and beta thyroid hormone receptor isoforms. J Biol Chem 268:10221-10227
    • (1943) J Biol Chem , vol.268 , pp. 10221-10227
    • Darling, D.S.1    Carter, R.L.2    Yen, P.M.3    Welborn, J.M.4    Chin, W.W.5    Umeda, P.K.6
  • 18
    • 0026495763 scopus 로고
    • New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone
    • Yen PM, Sugawara A, Refetoff S, Chin WW 1992 New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone. J Clin Invest 90:1825-1831
    • (1992) J Clin Invest , vol.90 , pp. 1825-1831
    • Yen, P.M.1    Sugawara, A.2    Refetoff, S.3    Chin, W.W.4
  • 19
    • 0025606855 scopus 로고
    • Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone
    • Sakurai A, Miyamoto T, Refetoff S, DeGroot LJ 1990 Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone. Mol Endocrinol 4:1988-1994
    • (1990) Mol Endocrinol , vol.4 , pp. 1988-1994
    • Sakurai, A.1    Miyamoto, T.2    Refetoff, S.3    DeGroot, L.J.4
  • 20
    • 0026042301 scopus 로고
    • Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors
    • Chatterjee VK, Nagaya T, Madison LD, Datta S, Rentoumis A, Jameson JL 1991 Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors. J Clin Invest 87:1977-1984
    • (1991) J Clin Invest , vol.87 , pp. 1977-1984
    • Chatterjee, V.K.1    Nagaya, T.2    Madison, L.D.3    Datta, S.4    Rentoumis, A.5    Jameson, J.L.6
  • 21
    • 0027469410 scopus 로고
    • The relative expression of mutant and normal thyroid hormone receptor genes in patients with generalized resistance to thyroid hormone determined by estimation of their specific messenger ribonucleic acid products
    • Hayashi Y, Janssen OE, Weiss RE, Murata Y, Seo H, Refetoff S 1993 The relative expression of mutant and normal thyroid hormone receptor genes in patients with generalized resistance to thyroid hormone determined by estimation of their specific messenger ribonucleic acid products. J Clin Endocrinol Metab 76:64-69
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 64-69
    • Hayashi, Y.1    Janssen, O.E.2    Weiss, R.E.3    Murata, Y.4    Seo, H.5    Refetoff, S.6
  • 24
    • 0025337579 scopus 로고
    • Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats
    • Strait KA, Schwartz HL, Perez-Castillo A, Oppenheimer JH 1990 Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats. J Biol Chem 265:10514-10521
    • (1990) J Biol Chem , vol.265 , pp. 10514-10521
    • Strait, K.A.1    Schwartz, H.L.2    Perez-Castillo, A.3    Oppenheimer, J.H.4
  • 25
    • 0026651722 scopus 로고
    • Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity
    • Schwartz HL, Strait KA, Ling NC, Oppenheimer JH 1992 Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity. J Biol Chem 267: 11794-11799
    • (1992) J Biol Chem , vol.267 , pp. 11794-11799
    • Schwartz, H.L.1    Strait, K.A.2    Ling, N.C.3    Oppenheimer, J.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.