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Volumn 38, Issue 3, 1997, Pages 409-418

Variables influencing tumor dosimetry in radioimmunotherapy of CEA- expressing cancers with anti-CEA and antimucin monoclonal antibodies

Author keywords

Carcinoembryonic antigen; Monoclonal antibodies; Radioimmunotherapy; Tumor dosimetry

Indexed keywords

CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HMN 14; MONOCLONAL ANTIBODY MN 14; MONOCLONAL ANTIBODY MU 9; MONOCLONAL ANTIBODY NP 4; MUCIN MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 0030959805     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (54)

References (40)
  • 1
    • 0029163551 scopus 로고
    • 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphoma
    • 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphoma. Lancet 1995;346:336-340.
    • (1995) Lancet , vol.346 , pp. 336-340
    • Press, O.W.1    Eary, J.F.2    Appelbaum, F.R.3
  • 3
    • 0028947670 scopus 로고
    • Phase I radioimmunotherapy trial with iodine-131-CC49 in metastatic colon carcinoma
    • Divgi CR, Scott AM, Dantis L, et al. Phase I radioimmunotherapy trial with iodine-131-CC49 in metastatic colon carcinoma. J Nucl Med 1995;36:586-592.
    • (1995) J Nucl Med , vol.36 , pp. 586-592
    • Divgi, C.R.1    Scott, A.M.2    Dantis, L.3
  • 4
    • 0028009261 scopus 로고
    • Comparison of equitoxic radioimmunotherapy and chemotherapy in the treatment of human colonic cancer xenografts
    • Blumenthal RD, Sharkey RM, Natale AM, et al. Comparison of equitoxic radioimmunotherapy and chemotherapy in the treatment of human colonic cancer xenografts. Cancer Res 1994;54:142-151.
    • (1994) Cancer Res , vol.54 , pp. 142-151
    • Blumenthal, R.D.1    Sharkey, R.M.2    Natale, A.M.3
  • 6
    • 1842384004 scopus 로고
    • In vivo localization of anti-CEA antibody in colon carcinoma. Can results obtained in the nude mice model be extrapolated to the patient situation?
    • Mach JP, Carrel S, Merenda C, Heumann D, Roenspies U. In vivo localization of anti-CEA antibody in colon carcinoma. Can results obtained in the nude mice model be extrapolated to the patient situation? Eur J Cancer 1978;(suppl I):113-120.
    • (1978) Eur J Cancer , Issue.1 SUPPL. , pp. 113-120
    • Mach, J.P.1    Carrel, S.2    Merenda, C.3    Heumann, D.4    Roenspies, U.5
  • 7
    • 0023909330 scopus 로고
    • Determination of tumor blood flow: A review
    • Jain RK. Determination of tumor blood flow: a review. Cancer Res 1988;48: 2641-2658.
    • (1988) Cancer Res , vol.48 , pp. 2641-2658
    • Jain, R.K.1
  • 8
    • 0022915868 scopus 로고
    • Tumor size: Effect on monoclonal antibody uptake in tumor nodules
    • Hagan PL, Halpem SE, Dillman RO, et al. Tumor size: effect on monoclonal antibody uptake in tumor nodules. J Nucl Med 1986;27:422-427.
    • (1986) J Nucl Med , vol.27 , pp. 422-427
    • Hagan, P.L.1    Halpem, S.E.2    Dillman, R.O.3
  • 9
    • 0023871842 scopus 로고
    • Tumor uptake as a function of tumor mass: A mathematical model
    • Williams LE, Duda RB, Proffitt RT, et al. Tumor uptake as a function of tumor mass: a mathematical model. J Nucl Med 1988;29:103-109.
    • (1988) J Nucl Med , vol.29 , pp. 103-109
    • Williams, L.E.1    Duda, R.B.2    Proffitt, R.T.3
  • 10
    • 0026763061 scopus 로고
    • The presence of a concomitant bulky tumor can decrease the uptake and therapeutic efficacy of radiolabeled antibodies in small tumors
    • Boerman OC, Sharkey RM, Blumenthal RD, Aninipot RL, Goldenberg DM. The presence of a concomitant bulky tumor can decrease the uptake and therapeutic efficacy of radiolabeled antibodies in small tumors. Int J Cancer 1992;51:470-475.
    • (1992) Int J Cancer , vol.51 , pp. 470-475
    • Boerman, O.C.1    Sharkey, R.M.2    Blumenthal, R.D.3    Aninipot, R.L.4    Goldenberg, D.M.5
  • 11
    • 0026739369 scopus 로고
    • Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
    • Juweid M, Neumann R, Paik C, et al. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res 1992;52:5144-5153.
    • (1992) Cancer Res , vol.52 , pp. 5144-5153
    • Juweid, M.1    Neumann, R.2    Paik, C.3
  • 12
    • 0029922060 scopus 로고    scopus 로고
    • Factors influencing the pharmacokinetics, dosimetry and diagnostic accuracy of radioimmunodetection and radioimmunotherapy of CEA-expressing tumors
    • Behr TM, Sharkey RM, Juweid ME, et al. Factors influencing the pharmacokinetics, dosimetry and diagnostic accuracy of radioimmunodetection and radioimmunotherapy of CEA-expressing tumors. Cancer Res 1996;56:1805-1816.
    • (1996) Cancer Res , vol.56 , pp. 1805-1816
    • Behr, T.M.1    Sharkey, R.M.2    Juweid, M.E.3
  • 16
    • 0025373376 scopus 로고
    • Murine monoclonal antibodies against carcinoembryonic antigen: Immunological, pharmacokinetic, and targeting properties in humans
    • Sharkey RM, Goldenberg DM, Goldenberg H, et al. Murine monoclonal antibodies against carcinoembryonic antigen: immunological, pharmacokinetic, and targeting properties in humans. Cancer Res 1990;50:2823-2831.
    • (1990) Cancer Res , vol.50 , pp. 2823-2831
    • Sharkey, R.M.1    Goldenberg, D.M.2    Goldenberg, H.3
  • 17
    • 0027406142 scopus 로고
    • Clinical evaluation of tumor targeting with a high-affinity, anticarcinoembryonic-antigen-specific, murine monoclonal antibody, MN-14
    • Sharkey RM, Goldenberg DM, Murthy S, et al. Clinical evaluation of tumor targeting with a high-affinity, anticarcinoembryonic-antigen-specific, murine monoclonal antibody, MN-14. Cancer 1993;71:2082-2096.
    • (1993) Cancer , vol.71 , pp. 2082-2096
    • Sharkey, R.M.1    Goldenberg, D.M.2    Murthy, S.3
  • 18
    • 0020701108 scopus 로고
    • Immunological heterogeneity of carcinoembryonic antigen: Antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies
    • Primus FJ, Newell KD, Blue A, Goldenberg DM. Immunological heterogeneity of carcinoembryonic antigen: antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies. Cancer Res 1983;43:686-692.
    • (1983) Cancer Res , vol.43 , pp. 686-692
    • Primus, F.J.1    Newell, K.D.2    Blue, A.3    Goldenberg, D.M.4
  • 19
    • 0028786364 scopus 로고
    • Evaluation of a CDR-grafted (humanized) anti-carcinoembryonic antigen (CEA) monoclonal antibody in preclinical and clinical studies
    • Sharkey RM, Juweid M, Shevitz J, et al. Evaluation of a CDR-grafted (humanized) anti-carcinoembryonic antigen (CEA) monoclonal antibody in preclinical and clinical studies. Cancer Res 1995;55:5935s-5945s.
    • (1995) Cancer Res , vol.55
    • Sharkey, R.M.1    Juweid, M.2    Shevitz, J.3
  • 20
    • 0028012632 scopus 로고
    • Phase I clinical evaluation of a new murine monoclonal antibody (Mu-9) against colon-specific antigen-p for targeting gastrointestinal carcinomas
    • Sharkey RM, Goldenberg DM, Vagg R, et al. Phase I clinical evaluation of a new murine monoclonal antibody (Mu-9) against colon-specific antigen-p for targeting gastrointestinal carcinomas. Cancer 1994;73:864-877.
    • (1994) Cancer , vol.73 , pp. 864-877
    • Sharkey, R.M.1    Goldenberg, D.M.2    Vagg, R.3
  • 21
    • 0021282561 scopus 로고
    • Absolute quantitation of radioactivity using the buildup factor
    • Wu RK, Siegel JA. Absolute quantitation of radioactivity using the buildup factor. Med Phys 1984;11:189-192.
    • (1984) Med Phys , vol.11 , pp. 189-192
    • Wu, R.K.1    Siegel, J.A.2
  • 22
    • 0025115337 scopus 로고
    • 131I-labeled anti-carcinoembryonic antigen monoclonal antibody
    • 131I-labeled anti-carcinoembryonic antigen monoclonal antibody. Cancer Res 1990; 50:1039s-1042s.
    • (1990) Cancer Res , vol.50
    • Siegel, J.A.1    Pawlyk, D.A.2    Lee, R.E.3
  • 27
    • 0020518295 scopus 로고
    • Relation between effective radiation dose and outcome of radioiodine therapy for thyroid cancer
    • Maxon HR, Thomas SR, Hertzberg VS, et al. Relation between effective radiation dose and outcome of radioiodine therapy for thyroid cancer. N Engl J Med 1983;309:937-941.
    • (1983) N Engl J Med , vol.309 , pp. 937-941
    • Maxon, H.R.1    Thomas, S.R.2    Hertzberg, V.S.3
  • 28
    • 0026100692 scopus 로고
    • Variables influencing tumor uptake of anti-melanoma monoclonal antibodies radioiodinated using para-iodobenzoyl (PIB) conjugate
    • Murray JL, Mujoo K, Wilmanns C, Mansfield P, Wilbur DS, Rosenblum MG. Variables influencing tumor uptake of anti-melanoma monoclonal antibodies radioiodinated using para-iodobenzoyl (PIB) conjugate. J Nucl Med 1991;32:279-287.
    • (1991) J Nucl Med , vol.32 , pp. 279-287
    • Murray, J.L.1    Mujoo, K.2    Wilmanns, C.3    Mansfield, P.4    Wilbur, D.S.5    Rosenblum, M.G.6
  • 29
    • 0022633795 scopus 로고
    • The effect of tumor CEA content and tumor size in tissue uptake of indium-111-labeled anti-CEA monoclonal antibody
    • Philben VJ, Jakowatz JG, Beatty BG, et al. The effect of tumor CEA content and tumor size in tissue uptake of indium-111-labeled anti-CEA monoclonal antibody. Cancer 1986;57:571-576.
    • (1986) Cancer , vol.57 , pp. 571-576
    • Philben, V.J.1    Jakowatz, J.G.2    Beatty, B.G.3
  • 30
    • 0024340282 scopus 로고
    • Effect of tumor mass and antigenic nature on the biodistribution of labeled monoclonal antibodies in mice
    • Watanabe Y, Endo K, Koizumi M, et al. Effect of tumor mass and antigenic nature on the biodistribution of labeled monoclonal antibodies in mice. Cancer Res 1989;49: 2884-2889.
    • (1989) Cancer Res , vol.49 , pp. 2884-2889
    • Watanabe, Y.1    Endo, K.2    Koizumi, M.3
  • 31
    • 0027398643 scopus 로고
    • Comparative dual label study of first and second generation antitumor-associated glycoprotein-72 monoclonal antibodies in colorectal cancer patients
    • Gallinger S, Reilly RM, Kirsh JC, et al. Comparative dual label study of first and second generation antitumor-associated glycoprotein-72 monoclonal antibodies in colorectal cancer patients. Cancer Res 1993;53:271-278.
    • (1993) Cancer Res , vol.53 , pp. 271-278
    • Gallinger, S.1    Reilly, R.M.2    Kirsh, J.C.3
  • 32
    • 0028091164 scopus 로고
    • Clinical comparison of radiolocalization of two monoclonal antibodies (mAbs) against the TAG-72 antigen
    • Divgi CR, Scott AM, McDermott K, et al. Clinical comparison of radiolocalization of two monoclonal antibodies (mAbs) against the TAG-72 antigen. Nucl Med Biol 1994;21:9-15.
    • (1994) Nucl Med Biol , vol.21 , pp. 9-15
    • Divgi, C.R.1    Scott, A.M.2    McDermott, K.3
  • 33
    • 0024413549 scopus 로고
    • Effect of dose, molecular size, affinity, and protein binding on rumor uptake of antibody or ligand: A biomathematical model
    • Thomas GD, Chappell MJ, Dykes PW, et al. Effect of dose, molecular size, affinity, and protein binding on rumor uptake of antibody or ligand: a biomathematical model. Cancer Res 1989;49:3290-3296.
    • (1989) Cancer Res , vol.49 , pp. 3290-3296
    • Thomas, G.D.1    Chappell, M.J.2    Dykes, P.W.3
  • 34
    • 0028269755 scopus 로고
    • A repertoire of monoclonal antibodies reveals extensive epitope heterogeneity in CEA purified from neoplasms originating from different organs
    • Hemando JJ, von Kleist S, Grunert F. A repertoire of monoclonal antibodies reveals extensive epitope heterogeneity in CEA purified from neoplasms originating from different organs. Int J Cancer 1994;56:655-661.
    • (1994) Int J Cancer , vol.56 , pp. 655-661
    • Hemando, J.J.1    Von Kleist, S.2    Grunert, F.3
  • 35
    • 0025667380 scopus 로고
    • The structure, metabolism and function of the carcinoembryonic antigen gene family
    • Thomas P, Toth CA, Saini KS, Jessup JM, Steele G. The structure, metabolism and function of the carcinoembryonic antigen gene family. Biochim Biophys Acta 1990; 1032:177-189.
    • (1990) Biochim Biophys Acta , vol.1032 , pp. 177-189
    • Thomas, P.1    Toth, C.A.2    Saini, K.S.3    Jessup, J.M.4    Steele, G.5
  • 37
    • 0023635232 scopus 로고
    • Anti-antibody enhancement of iodine-131 anti-CEA radioimmunodetection in experimental and clinical studies
    • Goldenberg DM, Sharkey RM, Ford E. Anti-antibody enhancement of iodine-131 anti-CEA radioimmunodetection in experimental and clinical studies. J Nucl Med 1987;28:1604-1610.
    • (1987) J Nucl Med , vol.28 , pp. 1604-1610
    • Goldenberg, D.M.1    Sharkey, R.M.2    Ford, E.3
  • 38
    • 0028056086 scopus 로고
    • Possible consequences of human antibody responses on the biodistribution of fragments of human, humanized or chimeric monoclonal antibodies: A note of caution
    • Pimm MV. Possible consequences of human antibody responses on the biodistribution of fragments of human, humanized or chimeric monoclonal antibodies: a note of caution. Life Sci 1994;55:45-49.
    • (1994) Life Sci , vol.55 , pp. 45-49
    • Pimm, M.V.1
  • 39
    • 0029394072 scopus 로고
    • Radioimmunotherapy of micrometastases: Side-stepping the solid-tumor hurdle
    • Sgouros G. Radioimmunotherapy of micrometastases: side-stepping the solid-tumor hurdle [Editorial]. J Nucl Med 1995;36:1910-1912.
    • (1995) J Nucl Med , vol.36 , pp. 1910-1912
    • Sgouros, G.1


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