Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: Comparison to class I proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2495-2500

  Reich, Ziv ^a   Altman, John D ^a   Boniface, J Jay ^a   Lyons, Daniel S ^a   Kozono, Haruo ^b   Ogg, Graham ^c   Morgan, Chantal ^d   Davis, Mark M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d California Institute of Technology   (United States)

Author keywords

free energy; thermal stability

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ARTICLE; CONFORMATIONAL TRANSITION; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN STABILITY; THERMOSTABILITY;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CIRCULAR DICHROISM; CRICETINAE; ENDOSOMES; HEAT; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-A2 ANTIGEN; HLA-B27 ANTIGEN; HYDROGEN-ION CONCENTRATION; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN DENATURATION; RECOMBINANT FUSION PROTEINS; THERMODYNAMICS;

MURINAE;

EID: 0030959548     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2495     Document Type: Article

References (48)

1. Germain, R. N. & Margulies, D. H. (1991) Annu. Rev. Immunol. 11, 403-450.
2. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennet, W. S., Strominger, J. L. & Wiley, D. C. (1987) Nature (London) 329, 506-512.
3. Brown, J. H., Jardetzky, T. S., Gorga, J. C., Stern, L. J., Urban, R. G., Strominger, J. L. & Wiley, D. C. (1993) Nature (London) 364, 33-39.
4. Ljunggren, H.-G., Stam, N. J., Öhlém, C., Neefjes, J. J., Höglund, P., Heemels, M. T., Bastin, J., Schumacher, T. N., Townsend, A., Karre, K. & Ploegh, H. L. (1990) Nature (London) 346, 476-480.
5. Kvist, S. & Hamann, U. (1990) Nature (London) 348, 446-448.
6. Hosken, N. A. & Bevan, M. J. (1990) Science 248, 367-370.
7. Ortiz-Navarrete, V. & Hämmerling, G. J. (1991) Proc. Natl. Acad. Sci. USA 88, 3594-3597.
8. Bouvier, M. & Wiley, D. C. (1994) Science 265, 398-402.
9. Fanestock, M. L., Tamir, I., Narhi, L. & Bjorkman, P. J. (1992) Science 258, 1658-1662.
10. Guo, H.-C., Madden, D. R., Silver, M. L., Jardetzky, T. S., Gorga, J. C., Strominger, J. L. & Wiley, D. C. (1993) Proc. Natl. Acad. Sci. USA 90, 8053-8057.
11. Parker, K. C., Bednarek, M. A., Hull, L. K., Utz, U., Cunningham, B., Zweerink, H. J., Biddison, W. E. & Coligan, J. E. (1992) J. Immunol. 149, 3580-3587.
12. Ruppert, J., Sidney, J., Celis, E., Kubo, R. T., Grey, H. M. & Sette, A. (1993) Cell 74, 929-937.
13. Saito, Y., Peterson, P. A. & Matsumura, M. (1993) J. Biol. Chem. 268, 21309-21317.
14. Germain, R. N. & Rinker, A. G. (1993) Nature (London) 363, 725-728.
15. Stern, L. J. & Wiley, D. C. (1992) Cell 68, 465-477.
16. Jensen, P. E. (1990) J. Exp. Med. 171, 1779-1784.
17. Sette, A., Southwood, S., O'Sullivan, D., Gaeta, F. C. A, Sidney, J. & Grey, H. M. (1992) J. Immunol. 148, 844-851.
18. Wettstein, D. A., Boniface, J. J., Reay, P. A., Schild, H. & Davis, M. M. (1991) J. Exp. Med. 174, 219-228.
19. Reay, P. A., Wettstein, D. A. & Davis, M. M. (1992) EMBO J. 11, 2829-2839.
20. Jensen, P. E. (1991) J. Exp. Med. 174, 1111-1120.
21. Dornmair, K., Rothenhausler, B. & McConnell, H. M. (1989) Cold Spring Harbor Symp. Quant. Biol. 54, 409-416.
22. Lee, J. M., Kay, C. M. & Watts, T. H. (1992) Int. Immunol. 4, 889-897.
23. Boniface, J. J., Lyons, D. S., Wettstein. D. A., Allbritton, N. L. & Davis, M. M. (1996) J. Exp. Med 183, 119-126.
24. Runnels, H. A., Moore, J. C. & Jensen, P. E. (1996) J. Exp. Med. 183, 127-136.
25. Sadegh-Nasseri, S. & Germain, R. N. (1991) Nature (London) 353, 167-170.
26. Matsui, K., Boniface, J. J., Reay, P. A., Schild, H., Fazekas de St. Groth, B. & Davis, M. M. (1991) Science 254, 1788-1791.
27. Boniface, J. J., Allbritton, N. L., Reay, P. A., Kantor, R. M., Stryer, L. & Davis, M. M. (1993) Biochemistry 32, 11761-11768.
28. Kozono, H., White, J., Clements, J., Marrack, P. & Kappler, J. (1994) Nature (London) 369, 151-154.
29. Ignatowicz, L., Winslow, G., Bill, J., Kappler, J. & Marrack, P. (1995) J. Immunol. 154, 3852-3862.
30. Kozono, H., Parker, D., White, J., Marrack, P. & Kappler, J. (1995) Immunity 3, 187-196.
31. Garboczi, D. N., Hung, D. T. & Wiley, D. C. (1992) Proc. Natl. Acad. Sci. USA 89, 3429-3433.
32. Privalov, P. L. & Gill, S. J. (1988) Adv. Protein Chem. 39, 191-234.
33. Greenfield, N. & Fasman, G. D. (1969) Biochemistry 8, 4108-4116.
34. Dornmair, K. & McConnell, H. M. (1990) Proc. Natl. Acad. Sci. USA 87, 4134-4138.
35. Creighton, T. E. (1993) Proteins (Freeman, New York) p. 293.
36. Driscoll, P. C., Altman, J. D., Boniface, J. J., Sakaguchi, K., Reay, P. A., Omichinski, J. G., Appella, E. & Davis, M. M. (1993) J. Mol. Biol. 232, 342-350.
37. Fremont, D. H., Hendrickson, W. A., Marrack, P. & Kappler, J. (1996) Science 272, 1001-1004.
38. Parker, K. C. & Strominger, J. L. (1985) Biochemistry 24, 5540-5550.
39. Stryhn, A., Pedersen, L. Ø., Romme, T., Olsen, A. C., Nissen, M. H., Thorpe, C. J. & Buus, S. (1996) J. Immunol. 156, 4191-4197.
40. Tulp, A., Verwoerd, D., Dobberstein, B., Ploegh, H. L. & Pieters, J. (1994) Nature (London) 369, 120-126.
41. Cresswell, P. (1994) Annu. Rev. Immunol. 12, 259-293.
42. Riberdy, J. M., Newcomb, J. R., Surman, M. J., Barbosa, J. A. & Cresswell, P. (1992) Nature (London) 360, 474-477.
43. Avva, R. R. & Cresswell, P. (1994) Immunity 1, 763-774.
44. Ghosh, P., Amaya, M., Mellins, E. & Wiley, D. C. (1995) Nature (London) 378, 457-462.
45. Weber, D. A., Evavold, B. D. & Jensen, P. E. (1996) Science 274, 618-620.
46. Sloan, S. V., Cameron, P., Porter, G., Gammon, M., Amaya, M., Mellins, E. & Zaller, D. M. (1995) Nature (London) 375, 802-806.
47. Yewdell, J. W. & Bennink, J. R. (1992) Adv. Immunol. 52, 1-123.
48. Bevan, M. J. (1989) Nature (London) 342, 478-479.