Photoaffinity labeling with UMP of lysine 992 of carbamyl phosphate synthetase from Escherichia coli allows identification of the binding site for the pyrimidine inhibitor

Biochemistry

Volumn 35, Issue 22, 1996, Pages 7247-7255

  Cervera, Javier ^a   Bendala, Elena ^a   Britton, Hubert G ^b   Bueso, Jorge ^a   Nassif, Zeina ^c   Lusty, Carol J ^c   Rubio, Vicente ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMOYL PHOSPHATE SYNTHASE; URIDINE PHOSPHATE;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

AFFINITY LABELS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA); CRICETINAE; CYANOGEN BROMIDE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; ESCHERICHIA COLI; HYDROXYLAMINE; HYDROXYLAMINES; LYSINE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PHOTOCHEMISTRY; SEQUENCE ALIGNMENT; URIDINE MONOPHOSPHATE;

ANIMALIA; CRICETINAE; ESCHERICHIA COLI;

EID: 0030010767     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952549u     Document Type: Article

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