메뉴 건너뛰기




Volumn 82, Issue 5, 1997, Pages 1421-1425

Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR STIMULATING AGENT; INSULIN; ISOPRENALINE; PHENYLISOPROPYLADENOSINE;

EID: 0030957207     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.5.1421     Document Type: Article
Times cited : (94)

References (39)
  • 1
    • 0018840897 scopus 로고
    • The polycystic ovary syndrome
    • Oxf.
    • Yen SSC. 1980 The polycystic ovary syndrome. Clin Endocrinol (Oxf). 12:177-207.
    • (1980) Clin Endocrinol , vol.12 , pp. 177-207
    • Yen, S.S.C.1
  • 2
    • 0028899597 scopus 로고
    • Hyperandrogenic anovulation (PCOS): A unique disorder of insulin notion associated with an increased risk of non-insulin-dependent diabetes mellitus
    • Dunaif A. 1995 Hyperandrogenic anovulation (PCOS): a unique disorder of insulin notion associated with an increased risk of non-insulin-dependent diabetes mellitus. Am J Med. 98(Suppl 1A):33S-39S.
    • (1995) Am J Med , vol.98 , Issue.SUPPL. 1A
    • Dunaif, A.1
  • 3
    • 0026391511 scopus 로고
    • Obesity and polycystic ovary syndrome
    • Franks SD. Kiddy P, Sharp A, et al. 1991 Obesity and polycystic ovary syndrome. Ann NlY Acad Sci. 626:201-206.
    • (1991) Ann NY Acad Sci , vol.626 , pp. 201-206
    • Franks, S.D.1    Kiddy, P.2    Sharp, A.3
  • 5
    • 0028345924 scopus 로고
    • Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance
    • Holte J, Bergh T, Berne C, Berglund L, Lithell H. 1994 Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance. J Clin Endocrinol Metab. 78:1052-1058.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1052-1058
    • Holte, J.1    Bergh, T.2    Berne, C.3    Berglund, L.4    Lithell, H.5
  • 6
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W, Dobrjansky A. 1989 Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes. 38:1165-1174.
    • (1989) Diabetes , vol.38 , pp. 1165-1174
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 7
    • 0029833087 scopus 로고    scopus 로고
    • Insulin, somatotrophic and LH axes in lean and obese women with polycystic ovary syndrome: Common and distinct features
    • Morales AJ, Laughlin GA, Butzow T, Maheshwari H, Baumann G, Yen SSC. 1996 Insulin, somatotrophic and LH axes in lean and obese women with polycystic ovary syndrome: common and distinct features. J Clin Endocrinol Metab. 81:2854-2864.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2854-2864
    • Morales, A.J.1    Laughlin, G.A.2    Butzow, T.3    Maheshwari, H.4    Baumann, G.5    Yen, S.S.C.6
  • 9
    • 0026699302 scopus 로고
    • Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome
    • Dunaif A, Segal KR, Shelley DR, et al. 1992 Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes. 41:1257-1266.
    • (1992) Diabetes , vol.41 , pp. 1257-1266
    • Dunaif, A.1    Segal, K.R.2    Shelley, D.R.3
  • 10
    • 0027941991 scopus 로고
    • Severe impairment of insulin action in adipocvtes from amenorrheic subjects with polcystic ovary syndrome
    • Marsden PJ, Murdoch A, Taylor R. 1994 Severe impairment of insulin action in adipocvtes from amenorrheic subjects with polcystic ovary syndrome. Metabolism. 43:1536-1542.
    • (1994) Metabolism , vol.43 , pp. 1536-1542
    • Marsden, P.J.1    Murdoch, A.2    Taylor, R.3
  • 11
    • 0020445542 scopus 로고
    • Modulation of insulin sensitivity by adenosine. Effects on glucose transport, lipid synthesis, and insulin receptors of the adipocyte
    • Joost HG, Steinfeld H-J. 1982 Modulation of insulin sensitivity by adenosine. Effects on glucose transport, lipid synthesis, and insulin receptors of the adipocyte. Mol Pharmacol. 22:614-618.
    • (1982) Mol Pharmacol , vol.22 , pp. 614-618
    • Joost, H.G.1    Steinfeld, H.-J.2
  • 12
    • 0023700763 scopus 로고
    • The role of adenosine in insulin action coupling in rat adipocytes
    • Ciaraldi TP. 1988 The role of adenosine in insulin action coupling in rat adipocytes. Mol Cell Endocrinol. 60:31-41.
    • (1988) Mol Cell Endocrinol , vol.60 , pp. 31-41
    • Ciaraldi, T.P.1
  • 13
    • 0027531568 scopus 로고
    • Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies
    • Steil GM, Volund A, Kahn SE, Bergman RN. 1993 Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes. 42:250-256.
    • (1993) Diabetes , vol.42 , pp. 250-256
    • Steil, G.M.1    Volund, A.2    Kahn, S.E.3    Bergman, R.N.4
  • 14
    • 0015146643 scopus 로고
    • Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays
    • Desbuquois B, Aurbach GD. 1971 Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J Clin Endocrinol Metab. 33:732-738.
    • (1971) J Clin Endocrinol Metab , vol.33 , pp. 732-738
    • Desbuquois, B.1    Aurbach, G.D.2
  • 15
    • 0025752281 scopus 로고
    • Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: Identification of multiple cellular defects in glucose transport
    • Ciaraldi TP, Molina JM, Olefsky JM. 1991 Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: identification of multiple cellular defects in glucose transport. J Clin Endocrinol Metab. 72:876-882.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 876-882
    • Ciaraldi, T.P.1    Molina, J.M.2    Olefsky, J.M.3
  • 16
    • 78651166782 scopus 로고
    • Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis
    • Rodbell M. 1964 Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem. 239:375-380.
    • (1964) J Biol Chem , vol.239 , pp. 375-380
    • Rodbell, M.1
  • 17
    • 0014239615 scopus 로고
    • Methods for the determination of adipose cell size in man and animals
    • Hirsch J, Gallian E. 1968 Methods for the determination of adipose cell size in man and animals. J Lipid Res. 9:110-119.
    • (1968) J Lipid Res , vol.9 , pp. 110-119
    • Hirsch, J.1    Gallian, E.2
  • 18
    • 0019909034 scopus 로고
    • 125I-insulin in adipocytes and IM-9 lymphocytes
    • 125I-insulin in adipocytes and IM-9 lymphocytes. J Biol Chem. 257:8667-8673.
    • (1982) J Biol Chem , vol.257 , pp. 8667-8673
    • Olefsky, J.M.1    Kao, M.2
  • 19
    • 0018388190 scopus 로고
    • Kinetic paramaters of 3-O-methylglucose and glucose in adipocytes
    • Whitesell RR, Gliemann J. 1979 Kinetic paramaters of 3-O-methylglucose and glucose in adipocytes. J Biol Chem. 254:5276-5283.
    • (1979) J Biol Chem , vol.254 , pp. 5276-5283
    • Whitesell, R.R.1    Gliemann, J.2
  • 20
    • 0020680990 scopus 로고
    • A peroxidase-coupled method for the colorometric determination of serum triglycerides
    • McGowan MW, Artiss JD, Strandbergh DR, Zak B. 1983 A peroxidase-coupled method for the colorometric determination of serum triglycerides. Clin Chem. 29:538-543.
    • (1983) Clin Chem , vol.29 , pp. 538-543
    • McGowan, M.W.1    Artiss, J.D.2    Strandbergh, D.R.3    Zak, B.4
  • 22
    • 0023633077 scopus 로고
    • Dissociation of in vitro sensitivities of glucose transport and antilipolysis to insulin in NIDDM
    • Yki-Jarvinen H, Kubo K, Zawadzki J, et al. 1987 Dissociation of in vitro sensitivities of glucose transport and antilipolysis to insulin in NIDDM. Am J Physiol. 253:E300-E304.
    • (1987) Am J Physiol , vol.253
    • Yki-Jarvinen, H.1    Kubo, K.2    Zawadzki, J.3
  • 23
    • 0028924485 scopus 로고
    • Adenosine effects upon insulin action on lipolysis and glucose transport in human adipocytes
    • Heseltine L, Webster JM, Taylor R. 1995 Adenosine effects upon insulin action on lipolysis and glucose transport in human adipocytes. Mol Cell Biochem. 144:147-151.
    • (1995) Mol Cell Biochem , vol.144 , pp. 147-151
    • Heseltine, L.1    Webster, J.M.2    Taylor, R.3
  • 24
    • 0016237090 scopus 로고
    • Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3′,5′-monophosphate, lipolysis, and glucose oxidation in fat cells
    • Schwabe U, Schonhofer PS, Ebert R. 1974 Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3′,5′-monophosphate, lipolysis, and glucose oxidation in fat cells. Eur J Physiol. 46:537-545.
    • (1974) Eur J Physiol , vol.46 , pp. 537-545
    • Schwabe, U.1    Schonhofer, P.S.2    Ebert, R.3
  • 25
    • 0018397674 scopus 로고
    • Sensitivity of glucose uptake and lipolysis of white adipocytes of the rat to insulin and effects of some metabolites
    • Green A, Newsholme EA. 1979 Sensitivity of glucose uptake and lipolysis of white adipocytes of the rat to insulin and effects of some metabolites. Biochem J. 180:365-370.
    • (1979) Biochem J , vol.180 , pp. 365-370
    • Green, A.1    Newsholme, E.A.2
  • 26
    • 0023258846 scopus 로고
    • Antilipolytic action of insulin in abdominal adipocytes of obese subjects before and during energy restriction. Influence of adenosine deaminase
    • Kather H, Scheurer A, Schlierf G. 1987 Antilipolytic action of insulin in abdominal adipocytes of obese subjects before and during energy restriction. Influence of adenosine deaminase. Int J Obesity. 11:191-200.
    • (1987) Int J Obesity , vol.11 , pp. 191-200
    • Kather, H.1    Scheurer, A.2    Schlierf, G.3
  • 27
    • 0026610352 scopus 로고
    • Gi down-regulation as a mechanism for heterologous desensitization in adipocytes
    • Green AG, Milligan G, Dobias SB. 1992 Gi down-regulation as a mechanism for heterologous desensitization in adipocytes. J Biol Chem. 267:3223-3229.
    • (1992) J Biol Chem , vol.267 , pp. 3223-3229
    • Green, A.G.1    Milligan, G.2    Dobias, S.B.3
  • 28
    • 0019351298 scopus 로고
    • Effects of adenosine on lipolysis in human subcutaneous fat cells
    • Ohisalo JJ. 1981 Effects of adenosine on lipolysis in human subcutaneous fat cells. J Clin Endocrinol Metab. 52:359-363.
    • (1981) J Clin Endocrinol Metab , vol.52 , pp. 359-363
    • Ohisalo, J.J.1
  • 29
    • 0021335438 scopus 로고
    • Inhibition of adenosine 3′,5′-monophosphate accumulation and lipolysis by adenosine analogs in human subcutaneous adipocytes
    • Ohisalo JJ, Ranta S, Huhtaniemi IT. 1984 Inhibition of adenosine 3′,5′-monophosphate accumulation and lipolysis by adenosine analogs in human subcutaneous adipocytes. J Clin Endocrinol Metab. 58:32-35.
    • (1984) J Clin Endocrinol Metab , vol.58 , pp. 32-35
    • Ohisalo, J.J.1    Ranta, S.2    Huhtaniemi, I.T.3
  • 30
  • 31
    • 0020611072 scopus 로고
    • Adenosine and the control of lipolysis in rat adipocytes during pregnancy and lactation
    • Vernon RG, Finley E, Taylor E. 1983 Adenosine and the control of lipolysis in rat adipocytes during pregnancy and lactation. Biochem J. 216:121-128.
    • (1983) Biochem J , vol.216 , pp. 121-128
    • Vernon, R.G.1    Finley, E.2    Taylor, E.3
  • 32
    • 0018375007 scopus 로고
    • Adenosine, thyroid status and regulation of lipolysis
    • Ohisalo JJ, Stouffer JE. 1979 Adenosine, thyroid status and regulation of lipolysis. Biochem J. 178:249-251.
    • (1979) Biochem J , vol.178 , pp. 249-251
    • Ohisalo, J.J.1    Stouffer, J.E.2
  • 33
    • 0025737672 scopus 로고
    • Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity
    • Kaartinen JM, Hreniuk SP, Martin LF, Ranta S, LaNoue KF, Ohisalo JJ. 1991 Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity. Biochem J. 279:17-22.
    • (1991) Biochem J , vol.279 , pp. 17-22
    • Kaartinen, J.M.1    Hreniuk, S.P.2    Martin, L.F.3    Ranta, S.4    LaNoue, K.F.5    Ohisalo, J.J.6
  • 34
    • 0026486783 scopus 로고
    • 6-(phenylisopropyl)adenosine on lipolysis in fat cells of massively obese human subjects
    • 6-(phenylisopropyl)adenosine on lipolysis in fat cells of massively obese human subjects. Clin Sci. 83:589-592.
    • (1992) Clin Sci , vol.83 , pp. 589-592
    • Ohisalo, J.J.1    Kaartinen, J.M.2    Ranta, S.3
  • 35
    • 0024358191 scopus 로고
    • Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations
    • Koopmans SJ, Sips HCM, Bosman J, Radder JK, Krans HMJ. 1989 Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations. Endocrinology. 125:3044-3050.
    • (1989) Endocrinology , vol.125 , pp. 3044-3050
    • Koopmans, S.J.1    Sips, H.C.M.2    Bosman, J.3    Radder, J.K.4    Krans, H.M.J.5
  • 36
    • 0022369781 scopus 로고
    • Mechanisms of insulin resistance in non-insulin-dependent (Type II) diabetes
    • Olefsky JM, Ciaraldi TP, Kolterman OG. 1985 Mechanisms of insulin resistance in non-insulin-dependent (Type II) diabetes. Am Med J. 79(Suppl 3B):12-22.
    • (1985) Am Med J. , vol.79 , Issue.SUPPL. 3B , pp. 12-22
    • Olefsky, J.M.1    Ciaraldi, T.P.2    Kolterman, O.G.3
  • 37
    • 0029119085 scopus 로고
    • Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle
    • Dunaif A, Xia J, Book C-B, Schenker E, Tang Z. 1995 Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. J Clin Invest. 96:801-810.
    • (1995) J Clin Invest , vol.96 , pp. 801-810
    • Dunaif, A.1    Xia, J.2    Book, C.-B.3    Schenker, E.4    Tang, Z.5
  • 38
  • 39
    • 0028959136 scopus 로고
    • The genetics of polycystic ovary syndrome
    • Legro RS. 1995 The genetics of polycystic ovary syndrome. Am J Med. 98(Suppl 1A):9S-16S.
    • (1995) Am J Med , vol.98 , Issue.SUPPL. 1A
    • Legro, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.