Using the variance of pairwise differences to estimate the recombination rate

Genetical Research

Volumn 69, Issue 1, 1997, Pages 45-48

  Wakeley, John ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENETIC RECOMBINATION; GENETIC VARIABILITY; MATHEMATICAL MODEL; POPULATION; POPULATION MODEL; STATISTICAL ANALYSIS; VARIANCE;

COMPUTER SIMULATION; GENETICS, POPULATION; MODELS, GENETIC; RECOMBINATION, GENETIC;

EID: 0030954044     PISSN: 00166723     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0016672396002571     Document Type: Article

References (10)

1. Hey, J. & Wakeley, J. (1997). A coalescent estimator of the population recombination rate. Genetics, in press.
2. Hudson, R. R. (1983). Properties of a neutral allele model with intragenic recombination. Theoretical Population Biology 23, 183-201.
3. Hudson, R. R. (1987). Estimating the recombination parameter of a finite population model without selection. Genetical Research, Cambridge 50, 245-250.
4. Hudson, R. R. (1990). Gene genealogies and the coalescent process. In Oxford Surveys in Evolutionary Biology (ed. D. J. Futuyma & J. Antonovics), vol. 7. Oxford: Oxford University Press.
5. Pluzhnikov, A. & Donelly, P. (1996). Optimal sequencing for surveying molecular genetic diversity. Genetics, 144: 1247-1262.
6. Schaeffer, S.W. & Miller, E. L. (1993). Estimation of linkage disequilibrium and the recombination parameter determined from segregating nucleotide sites in the alcohol dehydrogenase region of Drosophila pseudoobscura. Genetics 135, 541-552.
7. Tajima, F. (1983). Evolutionary relationship of DNA sequences in finite populations. Genetics 105, 437-460.
8. Tajima, F. (1993). Measurement of DNA polymorphism. In Mechanisms of Molecular Evolution (ed. N. Takahata & A. G. Clark). Sunderland, Mass.: Sinauer Associates.
9. Wakeley, J. (1996). Distinguishing migration from isolation using the variance of pairwise differences. Theoretical Population Biology 49, 369-386.
10. Watterson, G. A. (1975). On the number of segregating sites in genetical models without recombination. Theoretical Population Biology 7, 256-276.