A coalescent estimator of the population recombination rate

Genetics

Volumn 145, Issue 3, 1997, Pages 833-846

  Hey, Jody ^a   Wakeley, John ^b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BASE PAIRING; DNA POLYMORPHISM; DNA SEQUENCE; GENEALOGY; GENETIC RECOMBINATION; GENETIC VARIABILITY; GENOME; HUMAN; MUTATION RATE; POPULATION GENETICS; PRIORITY JOURNAL; PROBABILITY; RELIABILITY; THEORY;

GENETICS, POPULATION; RECOMBINATION, GENETIC;

EID: 0031035812     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. EWENS, W. J., 1979 Mathematical Population Genetics. Springer Verlag, New York.
2. FULLERTON-, S. M., R. M. HORDING, A.J. BovcE andj. B. CLEGG, 1994 Molecular and population genetic analysis of allelic sequence diversity at the human β-globin locus. Proc. Natl. Acad. Sci. USA 91: 1805-1809.
3. GRIFFITHS, R. C., 1981 Neutral two-locus multiple allele models with recombination. Theor. Pop. Biol. 19: 169-186.
4. HEY, J., 1991 A multi-dimensional coalescent process applied to multi-allelic selection models and migration models. Theor. Pop. Biol. 39: 30-48.
5. HIUJKER, A.J., G. HARAUZ, A. G. REAUME, M. GRAY, S. H. CIARK et al, 1994 Meiotic gene conversion tract length distribution within the rosy locus of Drosophila melanogaster. Genetics 137: 1019-1026.
6. HUDSON-, R. R., 1983a Properties of a neutral allele model with intragenic recombination. The'or. Pop. Biol. 23: 183-201.
7. HUDSON, R. R., 1983b Testing the constant-rate neutral allele model with protein sequence data. Evolution 37: 203-217.
8. HUDSON, R. R., 1987 Estimating the recombination parameter of a finite population model without selection. Genet. Res. Camb. 50: 245-250.
9. HUDSON, R. R., 1990 Gene genealogies and the coalescent process, pp. 1-44 in Oxford Surveys in Evolutionary Biology, Vol. 7, edited by P. H. HARVEY and L. PARTRIDGE. Oxford University Press, NewYork.
10. HUDSON, R. R., and N. L. KAFLAN, 1985 Statistical properties of the number of recombination events in the history of a sample of DNA sequences. Genetics 111: 147-164.
11. HUDSON, R. R., M. KREITMAN and M. AGUADé, 1987 A test of neutral molecular evolution based on nucleotide data. Genetics 116: 153-159.
12. JUKES, T. H., and C. R. CANTOR, 1969 Evolution of protein molecules, pp. 21-132 in Mammalian Protein Metabolism, edited by H. N. MUNRO. Academic Press, New York.
13. KIMURA, M., 1969 The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations. Genetics 61: 893-903.
14. KIXGMAN, J. F. C., 1982a The coalescent. Stochastic Process. Appl. 13: 235-248.
15. KIXGMAN, J. F. C., 1982b On the genealogy of large populations. J. Appl. Prob. 19A: 27-43.
16. KIRBY, D. A., and S. WOLFGANG, 1995 Haplotype test reveals departure from neutrality in a segment of the white gene of Drosophila melanogaster. Genetics 141: 1483-1490.
17. KLIMAN, R. M., and J. HEY, 1994 Reduced natural selection associated with low recombination in Drosophila melanogaster. Mol. Biol. Evol. 10: 1239-1258.
18. KRErTMAN, M., 1983 Nucleotide polymorphism at the alcohol dehydrogenaseoca& of Drosophila melanogaster. Nature 304: 412-417.
19. KUHNER, M. K., J. YAMATO and J. FELSENSTEIN, 1995 Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling. Genetics 140: 1421-1430.
20. McKANE, M., and R. MILKMAN, 1995 Transduction, restriction and recombination patterns in Escherichia coli. Genetics 139: 35-43.
21. SCHAEFFER, S. W., and E. L. MILLER, 1993 Estimates of linkage disequilibrium and the recombination parameter determined from segregating nucleotide sites in the alcohol dehydrogenase region of Drosophila pseudoobscura. Genetics 135: 541-552.
22. STEPHENS, J. C., 1985 Statistical methods of DNA sequence analysis: detection of intragenic recombination or gene conversion. Mol. Biol. Evol. 2: 539-556.
23. TAJIMA, F., 1983 Evolutionary relationships of DNA sequences in finite populations. Genetics 105: 437-460.
24. TAJIMA, F., 1989a The effect of change in population size on DNA polymorphism. Genetics 123: 597-601.
25. TAJIMA, F., 1989b Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123: 585-595.
26. TAJIMA, F., 1993 Measurement of DNA polymorphism, pp. 37-59 in Mechanisms of Molecular Evolution, edited by N. TAKAHATA and A. G. CLARKE. Sinauer Associates, Sunderland, MA.
27. VIGILANT, L., M. STONEKING, H. HARPENDING, K. HAWKES and A. C. WILSON, 1991 African populations and the evolution of human mitochondrial DNA. Science 253: 1503-1507.
28. WAKELEY, J., 1993 Substitution rate variation among sites in hypervariable region 1 of human mitochondrial DNA.J. Mol. Evol. 37: 613-623.
29. WATTERSON, G. A., 1975 On the number of segregating sites in genetical models without recombination. Theor. Pop. Biol. 7: 256275.