Regulation of human renin mRNA expression and protein release in transgenic mice

Hypertension

Volumn 28, Issue 2, 1996, Pages 290-296

  Thompson, Mark W ^a,b   Smith, Shane B ^a   Sigmund, Curt D ^a  

^a UNIVERSITY OF IOWA   (United States)

^b WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

gene expression regulation; genetics; mice, transgenic; renin angiotensin system

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; GENE EXPRESSION; HYPERTENSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENIN RELEASE;

EID: 0029743370     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.28.2.290     Document Type: Article

References (35)

1. Rapp JP, Wang SM, Dene H. A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science. 1989; 243:542-544.
2. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel J, Corvol P. Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992;71:169-180.
3. Prart RE, Flynn JA, Hobart PM, Paul M, Dzau VJ. Different secretory pathways of renin from mouse cells transfected with the human renin gene. J Biol Chem. 1988;263:3137-3141.
4. Lang JA, Yang G, Kern JA, Sigmund CD. Endogenous human renin expression and promoter activity in a pulmonary carcinoma cell line (Calu-6). Hypertension. 1995;25:704-710.
5. Sigmund CD, Jones CA, Kane CM, Wu C, Lang JA, Gross KW. Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice. Circ Res. 1992;70:1070-1079.
6. Sigmund CD. Expression of the human renin gene in transgenic mice throughout ontogeny. Pediatr Nephrol. 1993;7:639-645.
7. Fukamizu A, Seo MS, Hatae T, Yokoyama M, Nomura T, Katsuki M, Murakami K. Tissue-specific expression of the human renin gene in transgenic mice. Biochem Biophys Res Commun. 1989;165:826-832.
8. Ganten D, Wagner J, Zeh K, Koeller M, Bader M, Michel JB, Paul M, Zimmermann F, Ruf P, Hilgenfeld U, Ganten U, Kaling M, Bachmann S, Mullins JJ, Murakami K. Species-specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc Natl Acad Sci U S A. 1992;89:7806-7810.
9. Miller CCJ, Samani NJ, Carter AT, Brooks JI, Brammar WJ. Modulation of mouse renin gene expression by dietary sodium chloride intake in one-gene, two-gene and transgenic animals. J Hypertens. 1989;7:861-863.
10. Fukamizu A, Sugimura K, Takimoto E, Sugiyama F, Seo M-S, Takahashi S, Hatae T, Kajiwara N, Yagami K, Murakami K. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J Biol Chem. 1993;268:11617-11621.
11. Hackenthal E, Paul M, Ganten D, Taugner R. Morphology, physiology, and molecular biology of renin secretion. Physiol Rev. 1990; 70:1067-1116.
12. Yang G, Merrill DC, Thompson MW, Robillard JE, Sigmund CD. Functional expression of the human angiotensinogen gene in transgenic mice. J Biol Chem. 1994;269:32497-32502.
13. Merrill DC, Thompson MW, Carney C, Schlager G, Robillard JE, Sigmund CD. Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest. 1996;97:1047-1055.
14. Yamamoto J. Role of renin-angiotensin system in experimental hypertension in rats: plasma renin and hypotensive effect of angiotensin II antagonist. Jpn Circ J. 1977;41:665-675.
15. Yamamoto J, Matsunaga M, Hara A, Pak C, Kira J, Ogino K, Kawai C. Plasma renin and the antihypertensive effect of angiotensin-II antagonist in experimental hypertension. Jpn Circ J. 1976;40:895-899.
16. Leenen FH, McDonald RHJ. Effect of isoproterenol on blood pressure, plasma renin activity, and water intake in rats. Eur J Pharmacol. 1974;26:129-135.
17. Pettinger WA, Campbell WB, Keeton K. Adrenergic component of renin release induced by vasodilating antihypertensive drugs in the rat. Circ Res. 1973;33:82-86.
18. Skinner S, Bouhnik J, Huang H, Gonzalez M-F, Ménard J, Corvol P. Plasma angiotensin in binephrectomised mice. Clin Exp Hypertens. 1995;17:847-860.
19. Tokita Y, Franco-Saenz R, Mulrow PJ, Ganten D. Effects of nephrectomy and adrenalectomy on the renin-angiotensin system of transgenic rats TGR(mRen2)27. Endocrinology. 1994;134:253-257.
20. Tokita Y, Franco-Saenz R, Reimann EM, Mulrow PJ. Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen. Hypertension. 1994;23:422-427.
21. Johns DW, Peach MJ, Gomez RA, Inagami T, Carey RM. Angiotensin II regulates renin gene expression. Am J Physiol. 1990;259: F882-F887.
22. Burnier M, Brunner HR. Angiotensin II receptor antagonists and the kidney. Curr Opin Nephrol Hypertens. 1994;3:537-545. Review.
23. Zhuo J, Song K, Abdelrahman A, Mendelsohn FA. Blockade by intravenous losartan of AT1 angiotensin II receptors in rat brain, kidney and adrenals demonstrated by in vitro autoradiography. Clin Exp Pharmacol Physiol. 1994;21:557-567.
24. Tufro-McReddie A, Johns DW, Geary KM, Dagli H, Everett AD, Chevalier RL, Carey RM, Gomez RA. Angiotensin II type 1 receptor: role in renal growth and gene expression during normal development. Am J Physiol. 1994;266:F911-F918.
25. Nakamura A, Johns EJ. Renal nerves, renin, and angiotensinogen gene expression in spontaneously hypertensive rats. Hypertension. 1995;25:581-586.
26. Page WV, Perlman S, Smith FG, Segar JL, Robillard JE. Renal nerves modulate kidney renin gene expression during the transition from fetal to newborn life. Am J Physiol. 1992;262:R459-R463.
27. Schricker K, Hamann M, Kaissling B, Kurtz A. Role of the macula densa in the control of renal renin gene expression in two-kidney/ one-clip rats. Pflugers Arch. 1994;427:42-46.
28. Zhang Y, Morgan T. Role of the macula densa in renin synthesis and secretion. Am J Hypertens. 1994;7:448-452.
29. Field LJ, Gross KW. Ren-1 and Ren-2 loci are expressed in mouse kidney. Proc Natl Acad Sci USA. 1985;82:6196-6200.
30. Catanzaro DF, Mullins JJ, Morris BJ. The biosynthetic pathway of renin in mouse submandibular gland. J Biol Chem. 1983;258: 7364-7368.
31. Lee MA, Böhm M, Kim S, Bachmann S, Bachmann J, Bader M, Ganten D. Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat. Hypertension. 1995; 25:570-580.
32. Jones CA, Sigmund CD, McGowan R, Kane-Haas C, Gross KW. Temporal and spatial expression of the murine renin genes during fetal development. Mol Endocrinol. 1990;4:375-383.
33. Sigmund CD, Jones CA, Fabian JR, Mullins JJ, Gross KW. Tissue and cell-specific expression of a renin promoter-T antigen reporter gene construct in transgenic mice. Biochem Biophys Res Commun. 1990;170:344-350.
34. Chen M, Schnermann J, Smart AM, Brosius FC, Killen PD, Briggs JP. Cyclic AMP selectively increases renin mRNA stability in cultured juxtaglomerular granular cells. J Biol Chem. 1993; 268:24138-24144.
35. Lang JA, Ying L, Morris BJ, Sigmund CD. Transcription and post-transcriptional mechanisms regulate expression of the human renin gene in Calu-6 cells. Am J Physiol. In press.